Vascular Surgery, C66 P489-516 Flashcards

(223 cards)

1
Q

What is atherosclerosis?

P489

A
Diffuse disease process in arteries;
atheromas containing cholesterol and
lipid form within the intima and inner
media, often accompanied by ulcerations
and smooth muscle hyperplasia
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is the common theory
of how atherosclerosis is
initiated?
P490

A

Endothelial injury → platelets adhere →
growth factors released → smooth
muscle hyperplasia/plaque deposition

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What are the risk factors for
atherosclerosis?
P490

A

Hypertension, smoking, diabetes
mellitus, family history, hypercholesterolemia,
high LDL, obesity,
and sedentary lifestyle

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What are the common sites
of plaque formation in
arteries?
P490

A
Branch points (carotid bifurcation),
tethered sites (superficial femoral artery
[SFA] in Hunter’s canal in the leg)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What must be present for a
successful arterial bypass
operation?
P490

A
  1. Inflow (e.g., patent aorta)
  2. Outflow (e.g., open distal popliteal
    artery)
  3. Run off (e.g., patent trifurcation
    vessels down to the foot)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is the major principle
of safe vascular surgery?
P90

A

Get proximal and distal control of the

vessel to be worked on!

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What does it mean to
“POTTS” a vessel?
P490

A

Place a vessel loop twice around a vessel
so that if you put tension on the vessel
loop, it will occlude the vessel

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q
What is the suture needle
orientation through graft
versus diseased artery in a
graft to artery anastomosis?
P490
A

Needle “in-to-out” of the lumen in
diseased artery to help tack down the
plaque and the needle “out-to-in” on the
graft

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What are the three layers of
an artery?
P490

A
  1. Intima
  2. Media
  3. Adventitia
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Which arteries supply the
blood vessel itself?
P490

A

Vaso vasorum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is a true aneurysm?

P490

A

Dilation ( >2x nL diameter) of all three

layers of a vessel

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is a false aneurysm
(a.k.a pseudoaneurysm)?
P490

A

Dilation of artery not involving all three
layers (e.g., hematoma with fibrous
covering)
Often connects with vessel lumen and
blood swirls inside the false aneurysm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What is “ENDOVASCULAR”
repair?
P491 (picture)

A

Placement of a catheter in artery and

then deployment of a graft intraluminally

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

PERIPHERAL VASCULAR DISEASE
Define the arterial anatomy:

P491 (picture)

A
  1. Aorta
  2. Internal iliac (hypogastric)
  3. External iliac
  4. Common femoral artery
  5. Profundi femoral artery
  6. Superficial femoral artery (SFA)
  7. Popliteal artery
  8. Trifurcation
  9. Anterior tibial artery
  10. Peroneal artery
  11. Posterior tibial artery
  12. Dorsalis pedis artery
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q
PERIPHERAL VASCULAR DISEASE
How can you remember the
orientation of the lower
exterior arteries below the
knee on A-gram?
P492
A

Use the acronym “LAMP”:
Lateral Anterior tibial
Medial Posterior tibial

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

PERIPHERAL VASCULAR DISEASE
What is peripheral vascular
disease (PVD)?
P492

A

Occlusive atherosclerotic disease in the

lower extremities

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q
PERIPHERAL VASCULAR DISEASE
What is the most
common site of arterial
atherosclerotic occlusion in
the lower extremities?
P492
A

Occlusion of the SFA in Hunter’s canal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

PERIPHERAL VASCULAR DISEASE
What are the symptoms of
PVD?
P492

A

Intermittent claudication, rest pain,
erectile dysfunction, sensorimotor
impairment, tissue loss

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

PERIPHERAL VASCULAR DISEASE
What is intermittent
claudication?
P492

A

Pain, cramping, or both of the lower
extremity, usually the calf muscle, after
walking a specific distance; then the
pain/cramping resolves after stopping for
a specific amount of time while standing;
this pattern is reproducible

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

PERIPHERAL VASCULAR DISEASE
What is rest pain?
P492

A

Pain in the foot, usually over the distal
metatarsals; this pain arises at rest
(classically at night, awakening the
patient)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

PERIPHERAL VASCULAR DISEASE
What classically resolves rest
pain?
P492

A

Hanging the foot over the side of the bed
or standing; gravity affords some extra
flow to the ischemic areas

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q
PERIPHERAL VASCULAR DISEASE
How can vascular causes of
claudication be differentiated
from nonvascular causes,
such as neurogenic
claudication or arthritis?
P492
A

History (in the vast majority of patients)
and noninvasive tests; remember,
vascular claudication appears after a
specific distance and resolves after a
specific time of rest while standing (not
so with most other forms of claudication)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q
PERIPHERAL VASCULAR DISEASE
What is the differential
diagnosis of lower extremity
claudication?
P492
A
Neurogenic (e.g., nerve entrapment/
discs), arthritis, coarctation of the aorta,
popliteal artery syndrome, chronic
compartment syndrome, neuromas,
anemia, diabetic neuropathy pain
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

PERIPHERAL VASCULAR DISEASE
What are the signs of PVD?
P493

A

Absent pulses, bruits, muscular atrophy,
decreased hair growth, thick toenails,
tissue necrosis/ulcers/infection

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
``` PERIPHERAL VASCULAR DISEASE What is the site of a PVD ulcer vs. a venous stasis ulcer? P493 ```
PVD arterial insufficiency ulcer—usually on the toes/foot Venous stasis ulcer—medial malleolus (ankle)
26
PERIPHERAL VASCULAR DISEASE What is the ABI? P493
Ankle to Brachial Index (ABI); simply, the ratio of the systolic blood pressure at the ankle to the systolic blood pressure at the arm (brachial artery) A:B; ankle pressure taken with Doppler; the ABI is noninvasive
27
``` PERIPHERAL VASCULAR DISEASE What ABIs are associated with normals, claudicators, and rest pain? P493 ```
Normal ABI— ≥1.0 | Claudicator ABI— <0.4
28
PERIPHERAL VASCULAR DISEASE Who gets false ABI readings? P493
Patients with calcified arteries, especially | those with diabetes
29
PERIPHERAL VASCULAR DISEASE What are PVRs? P493
``` Pulse Volume Recordings; pulse wave forms are recorded from lower extremities representing volume of blood per heart beat at sequential sites down leg Large wave form means good collateral blood flow (Noninvasive using pressure cuffs) ```
30
``` PERIPHERAL VASCULAR DISEASE Prior to surgery for chronic PVD, what diagnostic test will every patient receive? P493 ```
A-gram (arteriogram: dye in vessel and x-rays) maps disease and allows for best treatment option (i.e., angioplasty vs. surgical bypass vs. endarterectomy) Gold standard for diagnosing PVD
31
``` PERIPHERAL VASCULAR DISEASE What is the bedside management of a patient with PVD? P493 ```
1. Sheep skin (easy on the heels) 2. Foot cradle (keeps sheets/blankets off the feet) 3. Skin lotion to avoid further cracks in the skin that can go on to form a fissure and then an ulcer
32
PERIPHERAL VASCULAR DISEASE What are the indications for surgical treatment in PVD? P494
``` Use the acronym “STIR”: Severe claudication refractory to conservative treatment that affects quality of life/livelihood (e.g., can’t work because of the claudication) Tissue necrosis Infection Rest pain ```
33
PERIPHERAL VASCULAR DISEASE What is the treatment of claudication? P494
``` For the vast majority, conservative treatment, including exercise, smoking cessation, treatment of HTN, diet, aspirin, with or without Trental (pentoxifylline) ```
34
``` PERIPHERAL VASCULAR DISEASE How can the medical conservative treatment for claudication be remembered? P494 ```
``` Use the acronym “PACE”: Pentoxifylline Aspirin Cessation of smoking Exercise ```
35
PERIPHERAL VASCULAR DISEASE How does aspirin work? P494
``` Inhibits platelets (inhibits cyclooxygenase and platelet aggregation) ```
36
PERIPHERAL VASCULAR DISEASE How does Trental® (pentoxifylline) work? P494
Results in increased RBC deformity and flexibility (Think: pentoXifylline = RBC fleXibility)
37
PERIPHERAL VASCULAR DISEASE What is the risk of limb loss with claudication? P494
5% limb loss at 5 years (Think: 5 in 5), | 10% at 10 years (Think: 10 in 10)
38
PERIPHERAL VASCULAR DISEASE What is the risk of limb loss with rest pain? P494
>50% of patients will have amputation of | the limb at some point
39
``` PERIPHERAL VASCULAR DISEASE In the patient with PVD, what is the main postoperative concern? P494 ```
``` Cardiac status, because most patients with PVD have coronary artery disease; ≈20% have an AAA MI is the most common cause of postoperative death after a PVD operation ```
40
PERIPHERAL VASCULAR DISEASE What is Leriche’s syndrome? P495
``` Buttock Claudication, Impotence (erectile dysfunction), and leg muscle Atrophy from occlusive disease of the iliacs/distal aorta Think: “CIA”: Claudication Impotence Atrophy (Think: CIA spy Leriche) ```
41
PERIPHERAL VASCULAR DISEASE What are the treatment options for severe PVD? P495
1. Surgical graft bypass 2. Angioplasty—balloon dilation 3. Endarterectomy—remove diseased intima and media 4. Surgical patch angioplasty (place patch over stenosis)
42
PERIPHERAL VASCULAR DISEASE What is a FEM-POP bypass? P495 (picture)
Bypass SFA occlusion with a graft from the | FEMoral artery to the POPliteal artery
43
PERIPHERAL VASCULAR DISEASE What is a FEM-DISTAL bypass? P496 (picture)
``` Bypass from the FEMoral artery to a DISTAL artery (peroneal artery, anterior tibial artery, or posterior tibial artery) ```
44
PERIPHERAL VASCULAR DISEASE What graft material has the longest patency rate? P496
Autologous vein graft
45
PERIPHERAL VASCULAR DISEASE What is an “in situ” vein graft? P496
``` Saphenous vein is more or less left in place, all branches are ligated, and the vein valves are broken with a small hook or cut out; a vein can also be used if reversed so that the valves do not cause a problem ```
46
``` PERIPHERAL VASCULAR DISEASE What type of graft is used for above-the-knee FEM-POP bypass? P496 ```
Either vein or Gortex® graft; vein still has | better patency
47
``` PERIPHERAL VASCULAR DISEASE What type of graft is used for below-the-knee FEM-POP or FEM-DISTAL bypass? P496 ```
Must use vein graft; prosthetic grafts | have a prohibitive thrombosis rate
48
PERIPHERAL VASCULAR DISEASE What is DRY gangrene? P496
Dry necrosis of tissue without signs of | infection (“mummified tissue”)
49
PERIPHERAL VASCULAR DISEASE What is WET gangrene? P497
Moist necrotic tissue with signs of | infection
50
PERIPHERAL VASCULAR DISEASE What is blue toe syndrome? P497
Intermittent painful blue toes (or fingers) due to microemboli from a proximal arterial plaque
51
LOWER EXTREMITY AMPUTATIONS What are the indications? P497
Irreversible tissue ischemia (no hope for revascularization bypass) and necrotic tissue, severe infection, severe pain with no bypassable vessels, or if patient is not interested in a bypass procedure
52
LOWER EXTREMITY AMPUTATIONS Identify the level of the following amputations: P497 (picture)
1. Above-the-Knee Amputation (AKA) 2. Below-the-Knee Amputation (BKA) 3. Symes amputation 4. Transmetatarsal amputation 5. Toe amputation
53
LOWER EXTREMITY AMPUTATIONS What is a Ray amputation? P497
Removal of toe and head of metatarsal
54
ACUTE ARTERIAL OCCLUSION What is it? P498
Acute occlusion of an artery, usually by embolization; other causes include acute thrombosis of an atheromatous lesion, vascular trauma
55
``` ACUTE ARTERIAL OCCLUSION What are the classic signs/symptoms of acute arterial occlusion? P498 ```
``` The “six P’s”: Pain Paralysis Pallor Paresthesia Polar (some say Poikilothermia—you pick) Pulselessness (You must know these!) ```
56
``` ACUTE ARTERIAL OCCLUSION What is the classic timing of pain with acute arterial occlusion from an embolus? P498 ```
Acute onset; the patient can classically tell you exactly when and where it happened
57
ACUTE ARTERIAL OCCLUSION What is the immediate preoperative management? P498
1. Anticoagulate with IV heparin (bolus followed by constant infusion) 2. A-gram
58
ACUTE ARTERIAL OCCLUSION What are the sources of emboli? P498
``` 1. Heart—85% (e.g., clot from AFib, clot forming on dead muscle after MI, endocarditis, myxoma) 2. Aneurysms 3. Atheromatous plaque (atheroembolism) ```
59
``` ACUTE ARTERIAL OCCLUSION What is the most common cause of embolus from the heart? P498 ```
AFib
60
``` ACUTE ARTERIAL OCCLUSION What is the most common site of arterial occlusion by an embolus? P498 ```
Common femoral artery (SFA is the most common site of arterial occlusion from atherosclerosis)
61
ACUTE ARTERIAL OCCLUSION What diagnostic studies are in order? P498
1. A-gram 2. ECG (looking for MI, AFib) 3. Echocardiogram ( ± ) looking for clot, MI, valve vegetation
62
ACUTE ARTERIAL OCCLUSION What is the treatment? P499
``` Surgical embolectomy via cutdown and Fogarty balloon (bypass is reserved for embolectomy failure) ```
63
ACUTE ARTERIAL OCCLUSION What is a Fogarty? P499
Fogarty balloon catheter—catheter with a balloon tip that can be inflated with saline; used for embolectomy
64
ACUTE ARTERIAL OCCLUSION How is a Fogarty catheter used? P499
Insinuate the catheter with the balloon deflated past the embolus and then inflate the balloon and pull the catheter out; the balloon brings the embolus with it
65
``` ACUTE ARTERIAL OCCLUSION How many mm in diameter is a 12 French Fogarty catheter? P499 ```
Simple: To get mm from French measurements, divide the French number by ∏, or 3.14; thus, a 12 French catheter is 12/3 = 4 mm in diameter
66
``` ACUTE ARTERIAL OCCLUSION What must be looked for postoperatively after reperfusion of a limb? P499 ```
Compartment syndrome, hyperkalemia, renal failure from myoglobinuria, MI
67
ACUTE ARTERIAL OCCLUSION What is compartment syndrome? P499
Leg (calf) is separated into compartments by very unyielding fascia; tissue swelling from reperfusion can increase the intracompartmental pressure, resulting in decreased capillary flow, ischemia, and myonecrosis; myonecrosis may occur after the intracompartment pressure reaches only 30 mm Hg
68
``` ACUTE ARTERIAL OCCLUSION What are the signs/ symptoms of compartment syndrome? P499 ```
Classic signs include pain, especially after passive flexing/extension of the foot, paralysis, paresthesias, and pallor; pulses are present in most cases because systolic pressure is much higher than the minimal 30 mm Hg needed for the syndrome!
69
ACUTE ARTERIAL OCCLUSION Can a patient have a pulse and compartment syndrome? P499
YES!
70
ACUTE ARTERIAL OCCLUSION How is the diagnosis made? P499
History/suspicion, compartment pressure | measurement
71
ACUTE ARTERIAL OCCLUSION P500What is the treatment of compartment syndrome? P500
Treatment includes opening compartments via bilateral calf-incision fasciotomies of all four compartments in the calf
72
ABDOMINAL AORTIC ANEURYSMS What is it also known as? P500
AAA, or “triple A”
73
ABDOMINAL AORTIC ANEURYSMS What is it? P500 (picture)
Abnormal dilation of the abdominal aorta ( >1.5–2x normal), forming a true aneurysm
74
ABDOMINAL AORTIC ANEURYSMS What is the male to female ratio? P500
≈6:1
75
ABDOMINAL AORTIC ANEURYSMS By far, who is at the highest risk? P500
White males
76
ABDOMINAL AORTIC ANEURYSMS What is the common etiology? P500
Believed to be atherosclerotic in 95% | of cases; 5% inflammatory
77
ABDOMINAL AORTIC ANEURYSMS What is the most common site? P500
Infrarenal (95%)
78
ABDOMINAL AORTIC ANEURYSMS What is the incidence? P500
5% of all adults older than 60 years | of age
79
``` ABDOMINAL AORTIC ANEURYSMS What percentage of patients with AAA have a peripheral arterial aneurysm? P500 ```
20%
80
ABDOMINAL AORTIC ANEURYSMS What are the risk factors? P501
Atherosclerosis, hypertension, smoking, male gender, advanced age, connective tissue disease
81
ABDOMINAL AORTIC ANEURYSMS What are the symptoms? P501
``` Most AAAs are asymptomatic and discovered during routine abdominal exam by primary care physicians; in the remainder, symptoms range from vague epigastric discomfort to back and abdominal pain ```
82
ABDOMINAL AORTIC ANEURYSMS Classically, what do testicular pain and an AAA signify? P501
Retroperitoneal rupture with ureteral | stretch and referred pain to the testicle
83
ABDOMINAL AORTIC ANEURYSMS What are the risk factors for rupture? P501
Aneurysm diameter (value + progression), HTN, symptomatic, COPD
84
ABDOMINAL AORTIC ANEURYSMS What are the signs of rupture? P501
Classic triad of ruptured AAA: 1. Abdominal pain 2. Pulsatile abdominal mass 3. Hypotension
85
ABDOMINAL AORTIC ANEURYSMS By how much each year do AAAs grow? P501
≈3 mm/year on average (larger AAAs | grow faster than smaller AAAs)
86
``` ABDOMINAL AORTIC ANEURYSMS Why do larger AAAs rupture more often and grow faster than smaller AAAs? P501 ```
Probably because of Laplace’s law | wall tension = pressure x diameter
87
``` ABDOMINAL AORTIC ANEURYSMS What is the risk of rupture per year based on AAA diameter size? P501 ```
<5cm = 4% 5-7cm = 7% 7 cm = 20%
88
ABDOMINAL AORTIC ANEURYSMS What are other risks for rupture? P501
Hypertension, smoking, COPD
89
ABDOMINAL AORTIC ANEURYSMS Where does the aorta bifurcate? P501
At the level of the umbilicus; therefore, when palpating for an AAA, palpate above the umbilicus and below the xiphoid process
90
ABDOMINAL AORTIC ANEURYSMS What is the differential diagnosis? P501
Acute pancreatitis, aortic dissection, mesenteric ischemia, MI, perforated ulcer, diverticulosis, renal colic, etc.
91
ABDOMINAL AORTIC ANEURYSMS What are the diagnostic tests? P502
Use U/S to follow AAA clinically; other tests involve contrast CT scan and A-gram; A-gram will assess lumen patency and iliac/renal involvement
92
ABDOMINAL AORTIC ANEURYSMS What is the limitation of A-gram? P502
AAAs often have large mural thrombi, which result in a falsely reduced diameter because only the patent lumen is visualized
93
ABDOMINAL AORTIC ANEURYSMS What are the signs of AAA on AXR? P502
Calcification in the aneurysm wall, best seen on lateral projection (a.k.a. “eggshell” calcifications)
94
ABDOMINAL AORTIC ANEURYSMS What are the indications for surgical repair of AAA? P502
``` AAA >5.5 cm in diameter, if the patient is not an overwhelming high risk for surgery; also, rupture of the AAA, any size AAA with rapid growth, symptoms/ embolization of plaque ```
95
ABDOMINAL AORTIC ANEURYSMS What is the treatment? P502 (picture)
1. Prosthetic graft placement, with rewrapping of the native aneurysm adventitia around the prosthetic graft after the thrombus is removed; when rupture is strongly suspected, proceed to immediate laparotomy; there is no time for diagnostic tests! 2. Endovascular repair
96
ABDOMINAL AORTIC ANEURYSMS What is endovascular repair? P502
Repair of the AAA by femoral catheter | placed stents
97
ABDOMINAL AORTIC ANEURYSMS Why wrap the graft in the native aorta? P503
To reduce the incidence of enterograft | fistula formation
98
``` ABDOMINAL AORTIC ANEURYSMS What type of repair should be performed with AAA and iliacs severely occluded or iliac aneurysm(s)? P503 ```
Aortobi-iliac or aortobifemoral graft | replacement (bifurcated graft)
99
``` ABDOMINAL AORTIC ANEURYSMS What is the treatment if the patient has abdominal pain, pulsatile abdominal mass, and hypotension? P503 ```
Take the patient to the O.R. for emergent | AAA repair
100
``` ABDOMINAL AORTIC ANEURYSMS What is the treatment if the patient has known AAA and new onset of abdominal pain or back pain? P503 ```
CT scan: 1. Leak → straight to OR 2. No leak → repair during next elective slot
101
``` ABDOMINAL AORTIC ANEURYSMS What is the mortality rate associated with the following types of AAA treatment: Elective? P503 ```
Good; <4% operative mortality
102
``` ABDOMINAL AORTIC ANEURYSMS What is the mortality rate associated with the following types of AAA treatment: Ruptured? P503 ```
≈50% operative mortality
103
``` ABDOMINAL AORTIC ANEURYSMS What is the leading cause of postoperative death in a patient undergoing elective AAA treatment? P503 ```
Myocardial infarction (MI)
104
ABDOMINAL AORTIC ANEURYSMS What are the other etiologies of AAA? P503
Inflammatory (connective tissue diseases), mycotic (a misnomer because most result from bacteria, not fungi)
105
ABDOMINAL AORTIC ANEURYSMS What is the mean normal abdominal aortic diameter? P503
2 cm
106
ABDOMINAL AORTIC ANEURYSMS What are the possible operative complications? P503
MI, atheroembolism, declamping hypotension, acute renal failure (especially if aneurysm involves the renal arteries), ureteral injury, hemorrhage
107
``` ABDOMINAL AORTIC ANEURYSMS Why is colonic ischemia a concern in the repair of AAAs? P503 ```
Often the IMA is sacrificed during surgery; if the collaterals are not adequate, the patient will have colonic ischemia
108
ABDOMINAL AORTIC ANEURYSMS What are the signs of colonic ischemia? P504
``` Heme-positive stool, or bright red blood per rectum (BRBPR), diarrhea, abdominal pain ```
109
``` ABDOMINAL AORTIC ANEURYSMS What is the study of choice to diagnose colonic ischemia? P504 ```
Colonoscopy
110
ABDOMINAL AORTIC ANEURYSMS When is colonic ischemia seen postoperatively? P504
Usually in the first week
111
``` ABDOMINAL AORTIC ANEURYSMS What is the treatment of necrotic sigmoid colon from colonic ischemia? P504 ```
1. Resection of necrotic colon 2. Hartmann’s pouch or mucous fistula 3. End colostomy
112
``` ABDOMINAL AORTIC ANEURYSMS What is the possible longterm complication that often presents with both upper and lower GI bleeding? P504 ```
``` Aortoenteric fistula (fistula between aorta and duodenum) ```
113
ABDOMINAL AORTIC ANEURYSMS What are the other possible postoperative complications? P504
Erectile dysfunction (sympathetic plexus injury), retrograde ejaculation, aortovenous fistula (to IVC), graft infection, anterior spinal syndrome
114
ABDOMINAL AORTIC ANEURYSMS What is anterior spinal syndrome? P504
``` Classically: 1. Paraplegia 2. Loss of bladder/bowel control 3. Loss of pain/temperature sensation below level of involvement 4. Sparing of proprioception ```
115
``` ABDOMINAL AORTIC ANEURYSMS Which artery is involved in anterior spinal cord syndrome? P504 ```
Artery of Adamkiewicz—supplies the | anterior spinal cord
116
``` ABDOMINAL AORTIC ANEURYSMS What are the most common bacteria involved in aortic graft infections? P504 ```
1. Staphylococcus aureus 2. Staphylococcus epidermidis (usually late)
117
``` ABDOMINAL AORTIC ANEURYSMS How is a graft infection with an aortoenteric fistula treated? P504 ```
Perform an extra-anatomic bypass with | resection of the graft
118
ABDOMINAL AORTIC ANEURYSMS What is an extra-anatomic bypass graft? P505 (picture)
``` Axillofemoral bypass graft—graft not in a normal vascular path; usually, the graft goes from the axillary artery to the femoral artery and then from one femoral artery to the other (fem-fem bypass) ```
119
ABDOMINAL AORTIC ANEURYSMS What is an endovascular repair? P505
Placement of a stent proximal and distal to an AAA through a distant percutaneous access (usually through the groin); less invasive; long-term results pending
120
``` CLASSIC INTRAOP QUESTIONS DURING AAA REPAIR Which vein crosses the neck of the AAA proximally? P505 ```
Renal vein (left)
121
``` CLASSIC INTRAOP QUESTIONS DURING AAA REPAIR What part of the small bowel crosses in front of the AAA? P505 ```
Duodenum
122
``` CLASSIC INTRAOP QUESTIONS DURING AAA REPAIR Which large vein runs to the left of the AAA? P505 ```
IMV
123
``` CLASSIC INTRAOP QUESTIONS DURING AAA REPAIR Which artery comes off the middle of the AAA and runs to the left? P505 ```
IMA
124
``` CLASSIC INTRAOP QUESTIONS DURING AAA REPAIR Which vein runs behind the RIGHT common iliac artery? P506 ```
LEFT common iliac vein
125
CLASSIC INTRAOP QUESTIONS DURING AAA REPAIR Which renal vein is longer? P506
Left
126
MESENTERIC ISCHEMIA CHRONIC MESENTERIC ISCHEMIA What is it? P506
``` Chronic intestinal ischemia from long-term occlusion of the intestinal arteries; most commonly results from atherosclerosis; usually in two or more arteries because of the extensive collaterals ```
127
MESENTERIC ISCHEMIA CHRONIC MESENTERIC ISCHEMIA What are the symptoms? P506
Weight loss, postprandial abdominal pain, anxiety/fear of food because of postprandial pain, ± heme occult, ± diarrhea/vomiting
128
MESENTERIC ISCHEMIA CHRONIC MESENTERIC ISCHEMIA What is “intestinal angina”? P506
Postprandial pain from gut ischemia
129
MESENTERIC ISCHEMIA CHRONIC MESENTERIC ISCHEMIA What are the signs? P506
Abdominal bruit is commonly heard
130
MESENTERIC ISCHEMIA CHRONIC MESENTERIC ISCHEMIA How is the diagnosis made? P506
A-gram, duplex, MRA
131
``` MESENTERIC ISCHEMIA CHRONIC MESENTERIC ISCHEMIA What supplies blood to the gut? P506 ```
1. Celiac axis vessels 2. SMA 3. IMA
132
``` MESENTERIC ISCHEMIA CHRONIC MESENTERIC ISCHEMIA What is the classic finding on A-gram? P506 ```
Two of the three mesenteric arteries are occluded, and there is atherosclerotic narrowing of the third patent artery
133
``` MESENTERIC ISCHEMIA CHRONIC MESENTERIC ISCHEMIA What are the treatment options? P506 ```
Bypass, endarterectomy, angioplasty, | stenting
134
MESENTERIC ISCHEMIA ACUTE MESENTERIC ISCHEMIA What is it? P506
Acute onset of intestinal ischemia
135
MESENTERIC ISCHEMIA ACUTE MESENTERIC ISCHEMIA What are the causes? P506
1. Emboli to a mesenteric vessel from the heart 2. Acute thrombosis of long-standing atherosclerosis of mesenteric artery
136
``` MESENTERIC ISCHEMIA ACUTE MESENTERIC ISCHEMIA What are the causes of emboli from the heart? P507 ```
AFib, MI, cardiomyopathy, valve disease/ | endocarditis, mechanical heart valve
137
``` MESENTERIC ISCHEMIA ACUTE MESENTERIC ISCHEMIA What drug has been associated with acute intestinal ischemia? P507 ```
Digitalis
138
``` MESENTERIC ISCHEMIA ACUTE MESENTERIC ISCHEMIA To which intestinal artery do emboli preferentially go? P507 ```
Superior Mesenteric Artery (SMA)
139
``` MESENTERIC ISCHEMIA ACUTE MESENTERIC ISCHEMIA What are the signs/ symptoms of acute mesenteric ischemia? P507 ```
Severe pain—classically “pain out of proportion to physical exam,” no peritoneal signs until necrosis, vomiting/ diarrhea/hyperdefecation, ± heme stools
140
``` MESENTERIC ISCHEMIA ACUTE MESENTERIC ISCHEMIA What is the classic triad of acute mesenteric ischemia? P507 ```
1. Acute onset of pain 2. Vomiting, diarrhea, or both 3. History of AFib or heart disease
141
``` MESENTERIC ISCHEMIA ACUTE MESENTERIC ISCHEMIA What is the gold standard diagnostic test? P507 ```
Mesenteric A-gram
142
``` MESENTERIC ISCHEMIA ACUTE MESENTERIC ISCHEMIA What is the treatment of a mesenteric embolus? P507 ```
``` Perform Fogarty catheter embolectomy, resect obviously necrotic intestine, and leave marginal looking bowel until a “second look” laparotomy is performed 24 to 72 hours postoperatively ```
143
``` MESENTERIC ISCHEMIA ACUTE MESENTERIC ISCHEMIA What is the treatment of acute thrombosis? P507 ```
``` Papaverine vasodilator via A-gram catheter until patient is in the OR; then, most surgeons would perform a supraceliac aorta graft to the involved intestinal artery or endarterectomy; intestinal resection/second look as needed ```
144
MEDIAN ARCUATE LIGAMENT SYNDROME What is it? P507
Mesenteric ischemia resulting from narrowing of the celiac axis vessels by extrinsic compression by the median arcuate ligament
145
MEDIAN ARCUATE LIGAMENT SYNDROME What is the median arcuate ligament comprised of? P507
Diaphragm hiatus fibers
146
MEDIAN ARCUATE LIGAMENT SYNDROME What are the symptoms? P508
Postprandial pain, weight loss
147
MEDIAN ARCUATE LIGAMENT SYNDROME What are the signs? P508
Abdominal bruit in almost all patients
148
MEDIAN ARCUATE LIGAMENT SYNDROME How is the diagnosis made? P508
A-gram
149
MEDIAN ARCUATE LIGAMENT SYNDROME What is the treatment? P508
Release arcuate ligament surgically
150
``` CAROTID VASCULAR DISEASE ANATOMY Identify the following structures: P508 (picture) ```
1. Internal carotid artery 2. External carotid artery 3. Carotid “bulb” 4. Superior thyroid artery 5. Common carotid artery (Shaded area: common site of plaque formation)
151
``` CAROTID VASCULAR DISEASE ANATOMY What are the signs/ symptoms? P508 ```
Amaurosis fugax, TIA, RIND, CVA
152
``` CAROTID VASCULAR DISEASE ANATOMY Define the following terms: Amaurosis fugax P508 ```
Temporary monocular blindness (“curtain coming down”): seen with microemboli to retina; example of TIA
153
``` CAROTID VASCULAR DISEASE ANATOMY Define the following terms: TIA P508 ```
Transient Ischemic Attack: focal neurologic deficit with resolution of all symptoms within 24 hours
154
``` CAROTID VASCULAR DISEASE ANATOMY Define the following terms: RIND P509 ```
Reversible Ischemic Neurologic Deficit: transient neurologic impairment (without any lasting sequelae) lasting 24 to 72 hours
155
``` CAROTID VASCULAR DISEASE ANATOMY Define the following terms: CVA P509 ```
``` CerebroVascular Accident (stroke): neurologic deficit with permanent brain damage ```
156
``` CAROTID VASCULAR DISEASE ANATOMY What is the risk of a CVA in patients with TIA? P509 ```
≈10% a year
157
``` CAROTID VASCULAR DISEASE ANATOMY What is the noninvasive method of evaluating carotid disease? P509 ```
Carotid ultrasound/Doppler: gives | general location and degree of stenosis
158
``` CAROTID VASCULAR DISEASE ANATOMY What is the gold standard invasive method of evaluating carotid disease? P509 ```
A-gram
159
``` CAROTID VASCULAR DISEASE ANATOMY What is the surgical treatment of carotid stenosis? P509 ```
Carotid EndArterectomy (CEA): the removal of the diseased intima and media of the carotid artery, often performed with a shunt in place
160
``` CAROTID VASCULAR DISEASE ANATOMY What are the indications for CEA in the ASYMPTOMATIC patient? P509 ```
Carotid artery stenosis 60% (greatest benefit is probably in patients with >80% stenosis)
161
``` CAROTID VASCULAR DISEASE ANATOMY What are the indications for CEA in the SYMPTOMATIC (CVA, TIA, RIND) patient? P509 ```
Carotid stenosis >50%
162
``` CAROTID VASCULAR DISEASE ANATOMY Before performing a CEA in the symptomatic patient, what study other than the A-gram should be performed? P509 ```
Head CT
163
``` CAROTID VASCULAR DISEASE ANATOMY In bilateral high-grade carotid stenosis, on which side should the CEA be performed in the asymptomatic, right-handed patient? P509 ```
Left CEA first, to protect the dominant | hemisphere and speech center
164
``` CAROTID VASCULAR DISEASE ANATOMY What is the dreaded complication after a CEA? P509 ```
Stroke (CVA)
165
``` CAROTID VASCULAR DISEASE ANATOMY What are the possible postoperative complications after a CEA? P510 ```
CVA, MI, hematoma, wound infection, hemorrhage, hypotension/hypertension, thrombosis, vagus nerve injury (change in voice), hypoglossal nerve injury (tongue deviation toward side of injury—“wheelbarrow” effect), intracranial hemorrhage
166
``` CAROTID VASCULAR DISEASE ANATOMY What is the mortality rate after CEA? P510 ```
≈1%
167
``` CAROTID VASCULAR DISEASE ANATOMY What is the perioperative stroke rate after CEA? P510 ```
Between 1% (asymptomatic patient) and | 5% (symptomatic patient)
168
``` CAROTID VASCULAR DISEASE ANATOMY What is the postoperative medication? P510 ```
Aspirin (inhibits platelets by inhibiting | cyclo-oxygenase)
169
``` CAROTID VASCULAR DISEASE ANATOMY What is the most common cause of death during the early postoperative period after a CEA? P510 ```
MI
170
``` CAROTID VASCULAR DISEASE ANATOMY Define “Hollenhorst plaque”? P510 ```
Microemboli to retinal arterioles seen as | bright defects
171
CLASSIC CEA INTRAOP QUESTIONS What thin muscle is cut right under the skin in the neck? P510
Platysma muscle
172
``` CLASSIC CEA INTRAOP QUESTIONS What are the extracranial branches of the internal carotid artery? P510 ```
None
173
CLASSIC CEA INTRAOP QUESTIONS Which vein crosses the carotid bifurcation? P510
Facial vein
174
CLASSIC CEA INTRAOP QUESTIONS What is the first branch of the external carotid? P510
Superior thyroidal artery
175
CLASSIC CEA INTRAOP QUESTIONS Which muscle crosses the common carotid proximally? P510
Omohyoid muscle
176
CLASSIC CEA INTRAOP QUESTIONS Which muscle crosses the carotid artery distally? P510
Digastric muscle | Think: Digastric = Distal
177
``` CLASSIC CEA INTRAOP QUESTIONS Which nerve crosses approximately 1 cm distal to the carotid bifurcation? P511 ```
Hypoglossal nerve; cut it and the tongue will deviate toward the side of the injury (the “wheelbarrow effect”)
178
CLASSIC CEA INTRAOP QUESTIONS Which nerve crosses the internal carotid near the ear? P511
Facial nerve (marginal branch)
179
CLASSIC CEA INTRAOP QUESTIONS What is in the carotid sheath? P511
1. Carotid artery 2. Internal jugular vein 3. Vagus nerve (lies posteriorly in 98% of patients and anteriorly in 2%) 4. Deep cervical lymph nodes
180
SUBCLAVIAN STEAL SYNDROME What is it? P511 (picture)
Arm fatigue and vertebrobasilar insufficiency from obstruction of the left subclavian artery or innominate proximal to the vertebral artery branch point; ipsilateral arm movement causes increased blood flow demand, which is met by retrograde flow from the vertebral artery, thereby “stealing” from the vertebrobasilar arteries
181
SUBCLAVIAN STEAL SYNDROME Which artery is most commonly occluded? P512
Left subclavian
182
SUBCLAVIAN STEAL SYNDROME What are the symptoms? P512
Upper extremity claudication, syncopal attacks, vertigo, confusion, dysarthria, blindness, ataxia
183
SUBCLAVIAN STEAL SYNDROME What are the signs? P512
Upper extremity blood pressure discrepancy, bruit (above the clavicle), vertebrobasilar insufficiency
184
SUBCLAVIAN STEAL SYNDROME What is the treatment? P512
Surgical bypass or endovascular stent
185
RENAL ARTERY STENOSIS What is it? P512
Stenosis of renal artery, resulting in decreased perfusion of the juxtaglomerular apparatus and subsequent activation of the renin-angiotensin-aldosterone system (i.e., hypertension from renal artery stenosis)
186
RENAL ARTERY STENOSIS What is the incidence? P512
``` ≈10% to 15% of the U.S. population have HTN; of these, ≈4% have potentially correctable renovascular HTN Also note that 30% of malignant HTN have a renovascular etiology ```
187
RENAL ARTERY STENOSIS What is the etiology of the stenosis? P512
``` ≈66% result from atherosclerosis (men > women), ≈33% result from fibromuscular dysplasia (women > men, average age 40 years, and 50% with bilateral disease) Note: Another rare cause is hypoplasia of the renal artery ```
188
``` RENAL ARTERY STENOSIS What is the classic profile of a patient with renal artery stenosis from fibromuscular dysplasia? P512 ```
Young woman with hypertension
189
RENAL ARTERY STENOSIS What are the associated risks/clues? P512
Family history, early onset of HTN, HTN | refractory to medical treatment
190
RENAL ARTERY STENOSIS What are the signs/ symptoms? P513
Most patients are asymptomatic but may have headache, diastolic HTN, flank bruits (present in 50%), and decreased renal function
191
RENAL ARTERY STENOSIS What are the diagnostic tests? A-gram P513
Maps artery and extent of stenosis (gold | standard)
192
RENAL ARTERY STENOSIS What are the diagnostic tests? IVP P513
80% of patients have delayed nephrogram | phase (i.e., delayed filling of contrast)
193
``` RENAL ARTERY STENOSIS What are the diagnostic tests? Renal vein renin ratio (RVRR) P513 ```
If sampling of renal vein renin levels shows ratio between the two kidneys ≥1.5, then diagnostic for a unilateral stenosis
194
RENAL ARTERY STENOSIS What are the diagnostic tests? Captopril provocation test P513
Will show a drop in BP
195
RENAL ARTERY STENOSIS Are renin levels in serum ALWAYS elevated? P513
``` No: Systemic renin levels may also be measured but are only increased in malignant HTN, as the increased intravascular volume dilutes the elevated renin level in most patients ```
196
RENAL ARTERY STENOSIS What is the invasive nonsurgical treatment? P513
Percutaneous Renal Transluminal Angioplasty (PRTA)/stenting: With FM dysplasia: use PRTA With atherosclerosis: use PRTA/stent
197
RENAL ARTERY STENOSIS What is the surgical treatment? P513
Resection, bypass, vein/graft | interposition, or endarterectomy
198
``` RENAL ARTERY STENOSIS What antihypertensive medication is CONTRAINDICATED in patients with hypertension from renovascular stenosis? P513 ```
``` ACE inhibitors (result in renal insufficiency) ```
199
SPLENIC ARTERY ANEURYSM What are the causes? P513
Women—medial dysplasia | Men—atherosclerosis
200
RENAL ARTERY STENOSIS How is the diagnosis made? P514
Usually by abdominal pain → U/S or CT scan, in the O.R. after rupture, or incidentally by eggshell calcifications seen on AXR
201
RENAL ARTERY STENOSIS What is the risk factor for rupture? P514
Pregnancy
202
``` RENAL ARTERY STENOSIS What are the indications for splenic artery aneurysm removal? P514 ```
Pregnancy, >2 cm in diameter, symptoms, | and in women of childbearing age
203
RENAL ARTERY STENOSIS What is the treatment for splenic aneurysm? P514
Resection or percutaneous catheter embolization in high-risk (e.g., portal hypertension) patients
204
POPLITEAL ARTERY ANEURYSM What is it? P514
Aneurysm of the popliteal artery caused by atherosclerosis and, rarely, bacterial infection
205
POPLITEAL ARTERY ANEURYSM How is the diagnosis made? P514
Usually by physical exam → A-gram, U/S
206
``` POPLITEAL ARTERY ANEURYSM Why examine the contralateral popliteal artery? P514 ```
50% of all patients with a popliteal artery aneurysm have a popliteal artery aneurysm in the contralateral popliteal artery
207
``` POPLITEAL ARTERY ANEURYSM What are the indications for elective surgical repair of a popliteal aneurysm? P514 ```
1. ≥2 cm in diameter 2. Intraluminal thrombus 3. Artery deformation
208
``` POPLITEAL ARTERY ANEURYSM Why examine the rest of the arterial tree (especially the abdominal aorta)? P514 ```
``` 75% of all patients with popliteal aneurysms have additional aneurysms elsewhere; >50% of these are located in the abdominal aorta/iliacs ```
209
POPLITEAL ARTERY ANEURYSM What size of the following aneurysms are usually considered indications for surgical repair: Thoracic aorta? P514
>6.5 cm
210
POPLITEAL ARTERY ANEURYSM What size of the following aneurysms are usually considered indications for surgical repair: Abdominal aorta? P514
>5.5 cm
211
POPLITEAL ARTERY ANEURYSM What size of the following aneurysms are usually considered indications for surgical repair: Iliac artery? P515
>4 cm
212
POPLITEAL ARTERY ANEURYSM What size of the following aneurysms are usually considered indications for surgical repair: Femoral artery? P515
>2.5 cm
213
POPLITEAL ARTERY ANEURYSM What size of the following aneurysms are usually considered indications for surgical repair: Popliteal artery? P515
>2 cm
214
MISCELLANEOUS Define the following terms: “Milk leg” P515
``` A.k.a. phlegmasia alba dolens (alba  white): often seen in pregnant women with occlusion of iliac vein resulting from extrinsic compression by the uterus (thus, the leg is “white” because of subcutaneous edema) ```
215
``` MISCELLANEOUS Define the following terms: Phlegmasia cerulea dolens P515 ```
``` In comparison, phlegmasia cerulea dolens is secondary to severe venous outflow obstruction and results in a cyanotic leg; the extensive venous thrombosis results in arterial inflow impairment ```
216
MISCELLANEOUS Define the following terms: Raynaud’s phenomenon P515
Vasospasm of digital arteries with color changes of the digits; usually initiated by cold/emotion White (spasm), then blue (cyanosis), then red (hyperemia)
217
MISCELLANEOUS Define the following terms: Takayasu’s arteritis P515
Arteritis of the aorta and aortic branches, resulting in stenosis/occlusion/ aneurysms Seen mostly in women
218
MISCELLANEOUS Define the following terms: Buerger’s disease P515
``` A.k.a. thromboangiitis obliterans: occlusion of the small vessels of the hands and feet; seen in young men who smoke; often results in digital gangrene → amputations ```
219
MISCELLANEOUS What is the treatment for Buerger’s disease? P515
Smoking cessation, +/– sympathectomy
220
MISCELLANEOUS What is blue toe syndrome? P515
Microembolization from proximal atherosclerotic disease of the aorta resulting in blue, painful, ischemic toes
221
MISCELLANEOUS What is a “paradoxical embolus”? P516
``` Venous embolus gains access to the left heart after going through an intracardiac defect, most commonly a patent foramen ovale, and then lodges in a peripheral artery ```
222
MISCELLANEOUS What size iliac aneurysm should be repaired? P516
>4 cm diameter
223
MISCELLANEOUS What is Behçet’s disease? P516
Genetic disease with aneurysms from loss of vaso vasorum; seen with oral, ocular, and genital ulcers/inflammation (↑ incidence in Japan, Mediterranean)