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Flashcards in Ventricular system and CSF Deck (17)
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1

Where does the choroid plexus develop from?

The choroid plexus develops from cells in the walls of the ventricles

2

Developing arteries invaginate the roof of the ventricle to form the ...?

Choroid fissure

3

The involuted ependymal cells along with the vessels enlarge into villi and form the...?

Choroid plexus

4

Where is the choroidal plexus found in the adult brain?

It is found in the 3rd, 4th and lateral ventricles

5

What restricts the majority of the blood supply to the brain?

The BBB

6

Sites of the brain without BBB

circumventricular organs or pineal glandv

7

CSF rate of formation

CSF formation at a rate of ∼0.4 ml·min−1·g tissue−1 (similar to proximal renal tubule and pancreatic ducts); 500-600ml / day
Total amount of CSF in CNS amounts to 150ml and is replaced 3-4 x daily

8

What do "routine CSF parameters" include?

include protein, albumin, immunoglobulin, glucose, lactate, and cellular changes, as well as specific antigen and antibody testing for infectious agents

9

Normal CSF

Normal CSF is clear and colorless, contains little protein (15-45mg/dl), little immunoglobulins and only 1-5 cells/ml

10

Pinealoma

(arising from the pineal gland in the midbrain and often compressing the cerebral aqueduct)

11

Colloid cyst

rare glioma type, often found at the interventricular formamen

12

Ependymoma

5% of all gliomas, arising from the ependymal cells lining the ventricles; predilection for posterior fossa; predominantly found in children < 5 yrs)

13

Dementia, incontinence and gait disturbances

Normal pressure hydrocephalus

14

Idiopathic intracranial hypertension / pseudotumor cerebri

igmatic condition mostly seen in obese females of childbearing age
Symptoms include headache and visual disturbances (visual field disturbances to blindness) due to papilloaedema
Despite increased CSF pressure (raised opening pressure on lumbar puncture > 25cmH2O; normal 10-20) no imaging features of hydrocephalus
Management with weight loss, medication and potentially ventriculoperitoneal shunt

15

Enlarged blind spot?

Papilloedema

16

Bulging optic disc seen in opthalmoscope?

Papilloedema

17

Where is the canal of schlemm?

The iridocorneal angle