Ventricular system, Choroid plexus, CSF Flashcards
*Choroid plexus
produces CSF
The ventricular system is embryonically derived from…?
The neural tube
Where is the ventricular system in the spinal cord?
the central canal
Location of the lateral ventricle
In the cerebral hemispheres
The lateral ventricle is derived embryonically derived from…
telencephalon
*interventricular foramen
Connects the lateral ventricle (body) and the third ventricle
List the parts of the lateral ventricle
Frontal (anterior) horn
Body
Temporal (inferior) horn
Occipital (posterior) horn
Trigone (atrium)
*Septum pellucidum
Thin sheet that spans between the corpus callosum
and fornix in the midline
Separates the anterior horns of the two lateral
ventricles
Does the body of the lateral ventricle contain choroid plexus?
Yes
Does the occipital (posterior) horn of the lateral ventricle contain choroid plexus?
No
Does the temporal (inferior) horn of the lateral ventricle contain choroid plexus?
Yes
Does the trigone (atrium) horn of the lateral ventricle contain choroid plexus?
Yes
From what is the third ventricle derived embryonically?
diencephalon
With what does the third ventricle communicate?
Communicates with the lateral ventricle: interventricular foramen
With the 4th ventricle: cerebral aqueduct
Does the third ventricle contain choroid plexus?
Yes in it’s roof
From what is the cerebral aqueduct derived embryonically?
mesencephalon
Location of the cerebral aqueduct
in the midbrain
Does the cerebral aqueduct contain choroid plexus?
NO
Does the 4th ventricle contain choroid plexus?
Yes
How is the choroid plexus formed?
Formed by the invagination of the pia mater into the ventricles
*CSF
Clear, colorless, acellular fluid located in the cranial and spinal subarachnoid spaces and ventricular system
of the brain
Functions of the CSF
Buoyancy
The actual mass of the human brain is about 1400 grams; however, the net weight of the brain suspended in the CSF is equivalent to a mass of 25 grams.
The brain therefore exists in neutral buoyancy, which allows the brain to maintain its density without being impaired by its own weight.
Protection
CSF protects the brain tissue from injury when jolted or hit.
Chemical stability
CSF flows throughout the inner ventricular system in the brain and is absorbed back into the bloodstream, rinsing the metabolic waste from the central nervous system (CNS) through the blood-brain barrier. This allows for homeostatic regulation of the distribution of neuroendocrine factors, to which slight changes can cause problems or damage to the nervous system.
Waste removal
CSF is critical in the brain’s glymphatic system, the functional waste clearance pathway for the vertebrate CNS
Prevention of brain ischemia
Decreasing the amount of CSF in the limited space inside the skull decreases total intracranial pressure and facilitates blood perfusion.
*Hydrocephalus
Dilation of the cerebral ventricles caused by
blockage of the CSF flow.
Characterized by excessive accumulation of CSF in
the cerebral ventricles or subarachnoid space