Vestibular System Flashcards

1
Q

What is the overall function of the Vestibular system

A

Posture and balance

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2
Q

Where is the vestibular system located

A

In the inner ear, embedded in the temporal bone

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3
Q

What is the vestibular system composed of

A

series of fluid filled membraneous tubes = labyrinths

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4
Q

What is the apparatus of the vestibular system

A

3 semi circular canals
Utricle
Saccule

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5
Q

What is the position of the semi circular canals

A

Are three dimensional due to being all right angled to each other

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6
Q

What is the swelling at the base of each semicircular canal called

A

Ampulla

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7
Q

Where is the utricle located

A

Swelling at the base of all the semicircular canals connecting them all

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8
Q

Where is the saccule located

A

The swelling underneath the base of the utricle

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9
Q

Where is sensory hair cells located in the vestibular apparatus

A

The ampulla of semicircular canals
Saccule
Utricle

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10
Q

What is the collective name of the utricle and the saccule

A

Otolith organs

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11
Q

What is the overall function of the otolith organs utricle

A

Detects linear acceleration and encode the position of the head in space

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12
Q

What is the overall function of the otolith organs saccule

A

detects vertical movement

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13
Q

What is the overall function of the semicircular canals

A

Detects rotational acceleration

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14
Q

Where are the sensory cells of the semicircular canals embedded

A

The ampulla

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15
Q

What is the sensory receptors called inside the ampulla

A

Cristae

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16
Q

What does the cristae consist of

A

A cupula - a flexible gelatinous strucutre

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17
Q

How is the crisate arranged in the ampulla

A

Stretches over the width of the ampulla

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18
Q

What is further embed in the cupula of the ampulla

A

Cilia of hair cells, which act as receptor cells

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19
Q

What is the purpose of the cilia of hair cells in the cristae

A

Synapse directly with the sensory neurones of the vestibular nerve

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20
Q

How is the cilla of hair cells receptors activated

A

By the movement of the endolmlyph in the semicircular canal pushing the gelatinous cupola of the cristae

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21
Q

What moves first when rotation of the skull occurs

A

The ampulla

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22
Q

Why doesn’t the endolymph move at first on rotation

A

As isn’t embedded in the skull

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23
Q

How does the hair cells in the Cupula detect rotational acceleration

A

Due to the inertia of the endolymph producing a drag which bends the cupula in the opposite direction of rotational movement and overall activates the cilla

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24
Q

What cause the endolymph to catch up the the rotational speed

A

Rotating at a constant velocity for several seconds

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25
What is the affect of the endolymph catching up with the rotational speed
Endolymph now rotating at the same velocity so remove the sheering force, and cuppa no longer distorted
26
How does dizziness occur if you suddenly stop high velocity rotation
endolymph to continue to move due to momentum creating a continuing sense of movement
27
What is the two types of cilia hair cells
Kinocillium - single very large | Stereocillia - smaller series
28
What does distortion of the cilla in the direction of the Kinocillium cause
Depolarisation and increase discharge of the APs in the vestibular nerve
29
What does distortion of the cilia away from the Kinocillium lead to
Hyperpolorisation and decrease discharge of APs in the vestibular nerve
30
What does movement of the kinocillium allows the brain to determine
Movement in time and space
31
Why is the orientation of the cupula all slightly different
So the brain can build a 3D image of body position using the pattern of firing and inhibition received.
32
Where does the integration of the sensory information from vestibular apparatus take place
The cerebellum
33
When you stop rotating after rotating at constant velocity, what happens to the movement of endolymph and the cupola
The endolymph continue to move die to momentum But the sheering of the cupula is in the opposite direction that at the start
34
What is the name of the sensory receptors in the otolith organs
Maculae
35
How is the Maculae orientated in the utricle
In the horizontal plane
36
How is the Maculae orientated in the saccule
In the vertical plane
37
What is the structure of the maculae
Set of cilla which embed into the gelatinous mass called the otolith membrane
38
What is embedded into the otolith membrane
CaCO3 crystals called otoliths.
39
What affect the positioning of otolith crystals
Gravitational forces
40
What doesn't have much input on the positioning of the otolith crystals, why?
Endolymph | as otoliths have greater density
41
How do the macule in the utricle detect the tilting of you head
Tilting the head moves the otoliths and the otolith membrane in which they are embedded. This distorts the jelly, and moves the cilia
42
What head tilt moves the otoliths in the direction of the kinocillium resulting in depolarisation
Backward tilt
43
What occurs when the head it tilted forward
Otoliths move in the opposing direction of the kinocillium resulting in hyperpolorisation decreasing AP discharge
44
What do the vertically orientated macule in the saccule respond to
Vertical forces e.g. movement in a lift
45
What provides information of the orientation of the head when lying down
The macula in the saccule
46
Where does the information to the brain via the vestibular nerve all originate from
The three cristae of the semicircular canals | and the two macule of the otolith organs
47
Where does many sensory afferents of the vestibule nerve terminate
In the vestibular centres in the medulla
48
How does the cerebellar centres associate with the vestibular centres
By co-ordinating the postural muscles required to maintain balance
49
Where does vestibular nuclei receive input from
Proprioceptors signalling limb and body position, Neck, Eye muscles
50
What is the vestibular nuclei
cranial nuclei for the vestibular nerve
51
Where is the vestibular nuclei found
grouped in both the pons and the medulla in the brainstem
52
How and where do the projections from the vestibular nuclei project
Project ipsilaterally, bilaterally and contra-laterally to descending motor pathways and the extra ocular nuclei/muscles
53
How does vestibular nuclei project to the cerebral cortex
Via the thalamus
54
What does the vestibular nuclei project to the cerebral cortex
perception of movement and body position = kinaesthesia.
55
Name three vestibular system reflexes
Tonic labyrinthine reflex Dynamic righting reflex Vestibulo-occular relflex
56
What does the vestibule system reflexs involve
Vestibulocortical and vestibulospinal tracts
57
What occurs in the tonic labyrinthine reflex and how does it happen?
The axis of the head is kept in a constant relationship with the rest of the body. Use information from maculae and neck proprioceptors
58
What occurs in the dynamic righting reflex and how does it happen?
Rapid postural adjustments that are made to stop you falling when you trip. Long reflexes, involving extension of all limbs
59
How does vestibular apparatus have a strong connection to visual apparatus
Afferents from the semi-circular canals project and connect (within the vestibular nuclei) to afferent fibres travelling to the extraocular nuclei and thus have strong input to influencing eye movement.
60
What demonstrates the strong association between visual system and postural control
An increased difficulty experienced with balance when you close your eyes
61
How do people with vestibular apparatus destruction maintain good balance and how do they loose balance
Balance is good if movement is relatively slow and eyes are open Balance is lost if they close their eyes
62
What is the two vestibulo-ocular reflex
Static reflex | Dyanmic vestibular nystagmus
63
What occurs in the static reflex
When you tilt your head, the eyes intort/extort to compensate, so that over a certain range, the image stays the right way up
64
What occurs in the dynamic vestibular nystagmus
series of saccadic eye movements that rotate the eye against the direction of rotation of the head and body so that the original direction of gaze is preserved despite head rotating
65
What occurs when the eyeball comes to the end of its range of movement
The extent of eye movement is restricted so it rapidly flicks back (nystagmus) to looking straight ahead
66
Define nystagmus
Rapid involuntary movement of the eye
67
If the head is rotating right what is the direction of the nystagmus
Right
68
In Post rotary nystagmus (at the end of rotation and nystagmus has occurred in the direction of the rotation) Why then do you then get nystagmus in the opposing direction
As In the deceleration the endolymph is catching up and now pushing the cupula in the opposite direction
69
How in caloric stimulation when the ear is washed with either cold or warm fluid is the vestibular system stimulated
As fluid gets through the thin bones and sets up convection current affecting the endolymph
70
What is the affect of warm fluid >37C
Sets up nystagmus towards the affected side
71
What is the affect of cold fluid <37C
sets up nystagmus away from the affected side
72
What are the two tests that check vestibular function by investigating nystagmus s
Caloric stimualtion (ear washed with water) Post rotary nystagmus (rotated in a chair)
73
What is the symptoms experienced due to caloric stimulation
Nausea | Vomiting
74
Why is it good to test fro nystagmus
As shows if any lesions are present in the periphery to central vestibular pathways
75
Powerful maintained stimulation of the vestibular system can cause what
Kinetosis - motor sickness
76
Why does motion sickness/kinestosis occur in moving vehicles
Visual and vestibular system inputs to the cerebellum are in conflict
77
How does the cerebellum generate the symptoms of motion sickness
sends“sickness signal” to the hypothalamus to bring about the autonomic changes
78
What is the autonomic nervous symptoms caused by motion sickness
``` Nausea Vomiting decreased blood pressure Dizziness Sweating Pallor ``` = all equal autonomic
79
What symptoms does acute infection of vestibular apparatus - labyrinthitis
Autonomic Nervous system symptoms Vertigo
80
what is the symptoms of Mieinieres disease
Vertigo Nausea Nystamgus Tinnuitis
81
How does menieres disease affect vestibular function
as associated with overproduction of endolymph
82
What drugs is the inner ear sensitive towards
Streptomycin
83
How does a lesion of the brain stem affect vestibular function
Can cause nystagmus at rest