Virology Flashcards

(45 cards)

1
Q

Intracellular organisms unable to reproduce itself outside the host cell

A

virus

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2
Q

All viruses are haploid except for

A

RETROVIRUS

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3
Q

Virus multiplies by binary fission

True or False

A

False

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4
Q

entire infectious unit of virus

A

virion

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5
Q

internal core of virus

A

genome

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6
Q

protein coat that surrounds the genome

A

capsid

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7
Q

Subunits of capsid are called

A

CAPSOMERES

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8
Q

Type of capsomeres

A

icosahedral
helical
complex

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9
Q

Virus without envelope are classified as

A

NAKED

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10
Q

Viruses are resistant to

A

antimicrobial

antibacterial

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11
Q

Viruses can survive long periods at

A

-70degC when freeze dried

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12
Q

Viruses can be killed with ____ but are somewhat resistant to _____

A

moist heat

dry heat

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13
Q

These inactivates viruses

A

UV and XRAY irradiation

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14
Q

Inactivate viruses that have lipid envelope

A

Chloroform

Ether

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15
Q

Protein shell or coat that encloses the nucleic acid genome that is built
of structural units of a virion

A

Capsid

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16
Q

DNA (deoxyribonucleic acid) or RNA (ribonucleus acid)

A

Nucleic Acid

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17
Q

Nucleic acid + Capsid (Enclosed)

A

Nucleocapsid

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18
Q

Morphological units seen on the surface of particles and represent
clusters of structure units or polypeptide

A

Capsomeres

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19
Q

A lipid containing membrane that surrounds some viral particles.

20
Q

A lipid containing membrane that surrounds some viral particles.

21
Q

It is acquired during viral maturation by a budding process through a cell membrane

22
Q

Envelope viruses has a ______ appearance inside the envelope

23
Q

the smallest functional unit equivalent to building units of the capsid. Basic protein that acts as building blocks of the coat

A

Structural units- Protomers

24
Q

Lysis is required for __________ and not for ___________

A

icosahedral pattern

helical pattern

25
the most efficient arrangement for subunits in a closed shell
Cubic symmetry
26
observed with animal viruses is the
icosahedral pattern
27
protein subunits are bound in a periodic way to the viral nucleic acid, winding into a helix
Helical symmetry
28
mostly used to distinguish different types of RNA viruses
Baltimore Classification/Scheme
29
is a proteinaceous infectious material
PRION
30
PRION's structure is composed of
insoluble beta pleated sheet
31
PRION affects
NS such as fibrils and vacuole (spongy)
32
Normal cellular protein misfolded when a portion of its α-helical coil structure refolds to a β-sheet, producing a mutant protein May be secreted in the urine
Transmissible spongiform encephalopathies (TSE)
33
Animal infection: Scrapie
sheep
34
Animal infection: Chronic wasting disease
Mule, deer, and elk
35
Animal infection: Transmissible mink encephalopathy
Mink
36
a family of progressive neurodegenerative disorders that affect both humans and animals
Human infection- Prion diseases
37
Types of prions
Sporadic Genetic Variant Iatrogenic
38
What animal affects Bovine spongiform encephalopathy (BSE)
Cattle
39
Viral genomes contain information which:
ensures replication packaging alters structure
40
All are double stranded-DNA except
parvovirus
41
All are icosahedral DNA, except
Poxvirus(COMPLEX)
42
All are enveloped, Except
Papovavirus Adenovirus Parvovirus
43
All multiply in nucleus, Except
Poxvirus (cytoplasm)
44
Largest DNA virus
poxvirus
45
smallest DNA virus
Parvovirus