Virology

Question 1

Owl eye inclusions associated with

Answer 1

CMV

Question 1

HIV Coreceptor in early infection

Answer 1

CCR5 on macrophage

Question 2

Ebola is example of what type of virus

Answer 2

Filovirus

Question 2

High fever, black vomitus, jaundice

eosinophilic apoptotic globules (Councilman bodies)

Answer 2

Yellow fever

Question 2

CMV vs candida esophagitis findings:

Answer 2

CMV: linear ulcers

Candida: white plaques

Question 3

Ulcerative gum lesions with intranuclear inclusions in child 1-3 yo

Answer 3

HSV-1

Question 4

Generalized LAD including post-auricular and occipital in unvaccinated adult

Answer 4

Rubella

Question 5

Virus that binds to CR2 or CD21

Answer 5

EBV

Question 6

Rubella and equine encephalitis are examples of

Answer 6

Togavirus

Question 8

HBV replication stages

Answer 8

dsDNA –> Template +RNA –> dsDNA

Question 8

Supplementing which vitamin can reduce measles mortality in kids

Answer 8

A

Question 9

Name 5 picornaviruses

Answer 9

PERCH

Poliovirus

Echovirus

Rhinovirus

Coxsackievirus

HAV

Question 10

Naked (nonenveloped viruses):

Answer 10

Give **PAPP **smears and CPR to a naked Heppy

Papillomavirus

Adenovirus

Parvovirus

Polyomavirus

Calicivirus

Picornavirus

Reovirus

Hepevirus

PAPP = DNA

CPR & hepe = RNA

Question 10

Viruses with segmented genome, thus enabling reassortment (name 2)

Answer 10

Rotavirus

Orthomyxovirus

Question 10

HCV

Yellow Fever

Dengue

St. Louis encephalitis

West Nile virus

All are examples of?

Answer 10

Flavivirus

Question 11

Lassa fever encephalitis and lymphocytic choriomeningitis virus are examples of what type of virus?

Answer 11

Arenavirus

Question 12

Partially double stranded and circular

Answer 12

Hepadna

Question 13

Blueberry muffin appearance suggestive of extramedullary hematopoiesis

Answer 13

Rubella

Question 13

Parotitis

Orchitis

Meningitis

Answer 13

Mumps

Question 15

Non-enveloped ssDNA

Answer 15

Parvovirus

Question 16

Killed vaccines

Answer 16

Rabies

Influenza (injected)

Salk Polio

HAV

Question 17

HIV coreceptor in late infection

Answer 17

CXCR4 on T cells

Question 18

List the 7 DNA viruses

Answer 18

HHAPPPPy

Hepadna

Herpes

Adeno

Pox

Parvo

Papilloma

Polyoma

Question 19

Virus that acquires envelop from cell nuclear membrane

Answer 19

Herpesviruses (including CMV)

Question 21

Erythema infectiosum caused by

Answer 21

Parvovirus B19

Question 22

Most common global cause of infantile gastroenteritis

Answer 22

Rotavirus

Question 22

Function of gp41 in HIV

Answer 22

transmembrane -- fusion and entry

Question 24

4 most common causes of viral meningitis

Answer 24

Coxsackie Virus Echovirus Poliovirus Enterovirus

Question 24

hydrops fetalis associated with

Answer 24

parvo B19

Question 26

Which DNA viruses have ssDNA? dsDNA?

Answer 26

Everything has dsDNA except parvovirus "part of a virus"

Question 27

Common adult rubella complication

Answer 27

Arthralgia

Question 27

Function of gp120 in HIV

Answer 27

docking -- attachment to host CD4+ T cell

Question 29

JC virus and BK virus are in which viral family

Answer 29

Polyomavirus

Question 31

ssRNA w/ bullet shaped capsule studded with glycoprotein spikes Binds to AChR

Answer 31

rabies

Question 32

function of pol in HIV

Answer 32

gene coding for reverse transcriptase, aspartate protease and integrase

Question 33

Anti-HAV IgM vs Anti-HAV IgG

Answer 33

IgM: acute hepatitis IgG: prior infection and/or vaccination

Question 34

DNA virus that is not icosahedral, doesn't replicate in nucleus

Answer 34

Pox

Question 35

CCR5 mutations Homozygous: Heterozygous:

Answer 35

Homozygous: immune to HIV Heterozygous: slower course HIV

Question 37

Virus requiring HBsAg encapsulation

Answer 37

Hep D

Question 38

Bullet shaped virus Negri bodies Purkinje cells of cerebellum Hippocampal neurons

Answer 38

Rabies

Question 39

Site of replication: DNA vs RNA virus

Answer 39

DNA: nucleus RNA: cytosol Beware of exceptions: poxvirus, influenza, retrovirus FA pp 157

Question 40

CMV Envelope? Type of genetic material?

Answer 40

Enveloped dsDNA

Question 41

Coltivirus and rotavirus are examples of

Answer 41

Reovirus

Question 42

Virus that binds to erythrocyte P antigen

Answer 42

Parvo B19

Question 42

Intranuclear and cytoplasmic inclusion bodies in immunocompromised patient

Answer 42

CMV

Question 43

function of p24 in HIV

Answer 43

capsid protein

Question 44

Sole positive marker of HBV infection during window period

Answer 44

Anti-HBc IgM

Question 45

Fecal-oral hepatidides

Answer 45

HAV and HEV The vowels hit your bowels

Question 47

Name 4 segmented viruses

Answer 47

**BOAR** **B**unyavirus **O**rthomyxovirus **A**renaviruses **R**eovirus

Question 48

These naked nucleic acids are not infectious and require polymerases

Answer 48

dsRNA negative ssRNA

Question 50

High fever for several days causing diffuse maculopapular rash

Answer 50

Roseola

Question 51

Incubation period in HDV Superinfection: Coinfection:

Answer 51

Superinfection: Short (poor prognosis) Coinfection: Long

Question 52

3 circular RNA viruses

Answer 52

**ABD** **A**renavirus **B**unyavirus **D**elta virus

Question 54

Surface fusion protein (F protein) are present in this family of viruses

Answer 54

Paramyxovirus

Question 55

Name 6 negative-stranded RNA viruses

Answer 55

**A**lways **B**ring **P**olymerase **O**r **F**ail **R**eplication **A**renavirus **B**unyavirus **P**aramyxovirus **O**rthomyxovirus **F**iloviruses **R**habdoviruses

Question 56

Koplik spots Warthin-Finkeldey giant cells (fused lymphs) Coryza Conjunctivitis

Answer 56

Measles

Question 57

Mononucleosis-like symptoms but no heterophil antibodies

Answer 57

CMV

Question 58

In EBV, are atypical lymphocytes B cells or T cells? What type?

Answer 58

Cytotoxic T cells (not the infected B cells through CD21)

Question 59

All DNA viruses are linear except these are circular:

Answer 59

papilloma polyoma hepadnavirus

Question 60

Norovirus is example of

Answer 60

Calicivirus

Question 61

Only RNA virus that is double stranded

Answer 61

reovirus

Question 62

Positive stranded RNA viruses (name 7)

Answer 62

I went to a retro toga party where I drank flavored Corona and ate hippy California pickles Retro Toga Flav Corona hepe calici picorna