Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

Microbiology II > Virology > Flashcards

Virology Flashcards

(80 cards)

Start Studying
1
Q

T/F: all helical viruses are enveloped

A

True

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

T/F: all naked viruses are icosahedral

A

True

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Which viral protein is responsible for evasion of host defense?

A

Antigenic (serotypic) variants

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Lipid membrane is acquired as the virus exits from the cell in the process called

A

Budding

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

All enveloped viruses acquire envelope from plasma membrane except

A

Herpesvirus - from nuclear membrane

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

T/F: enveloped viruses are more stable and harder to inactivate

A

False

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Infectious/not infectious?: naked nucleic acids of (-) strand ssRNA and dsRNA viruses

A

Not infectious

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Infectious/not infectious?: purified nucleic acids of most dsDNA (except poxviruses and HBV)

A

Infectious

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Infectious/not infectious?: (+) strand genome ssRNA viruses

A

Infectious

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Cause of transmissible spongiform encephalopathies

A

Prions
Nonpathogenic as alpha-helix
Pathogenic as beta-pleated sheet

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

T/F: all viruses are haploid

A

False - retroviruses are not haploid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Viruses with segmented genomes

A 
BOAR
Bunyaviruses
Orthomyxoviruses (influenza)
Arenaviruses
Reoviruses (Rotavirus)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Negative-strand RNA viruses

A 
Always Bring Polymerase Or Fail Replication
Arenaviruses
Bunyaviruses
Paramyxoviruses
Orhtomyxoviruses
Filoviruses
Rhabdoviruses
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

When one virus produces a protein that can be used by another virus

A

Complementation

Eg. Hepatitis D and B

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

2 different viruses infect the same cell

A

Phenotypic mixing

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Responsible for causing epidemics

A

Genomic ressortment

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Phase in viral growth curve: no virus is detectable

A

Phase 2 eclipse period

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Phase in viral growth curve: amount of detectable viruses reached plateau

A

Phase 4 latent period

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Phase in viral growth curve: derrangement if cell function –> lysis and cell death, remarkable amplification in number of viral particles

A

Phase 5 cytopathic effect

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

What are the phases of the viral growth curve?

A 
Phase 0: entry
Phase 1: decline
Phase 2: eclipse period
Phase 3: rise period
Phase 4: latent period
Phase 5: cytopathic effect
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Phase in viral growth curve: viruses decrease in number but continues to function

A

Phase 1: decline

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Visual or functional change in infected cells

A

Cytopathic effect

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Oncogenic viruses induce transformation and unrestrained growth

A

Malignant transformation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Infected cells appear normal but are producing large numbers of progeny viruses

A

Commensal symbiosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Bind cytokines and block their ability to nteract with receptors on their intended targets
Cytokine decoys
26
Reduce the expression of antigen presenting cells and inactivate complement
Virokines
27
Produce viruse for long periods of time and can serve as a source of infection for others
Carrier state
28
Not producing virus at the present but can be reactivated at a subsequent time
Latent infections
29
Long incubation period, often measured in years
Slow virus infections
30
Laboratory diagnosis: definitive
Complement fixation, hemagglutination inhibition, neutralization, fluorescent-antibody assay, radioimmunoassay, ELISA
31
Gold standard in viral diagnosis
Presence of viral DNA or RNA
32
Killed vaccines
``` RIP Always Rabies Influenza Polio (Salk's) hepatitis A ```
33
Recombinant vaccines
Hepa B | HPV (types 6, 11, 16, 18)
34
Live attenuated vaccines
MMR (only live-attenuated may be given to HIV+ pts) Varicella Sabin's polio Yellow fever
35
DNA viruses
DNA viruses are HHAPPPPy viruses Hepadna, Herpes Adeno Pox, Parvo, Polyoma, Papilloma
36
The only DNA virus with a single-stranded DNA
Parvovirus (parvovirus B19)
37
All DNA viruses have a LINEAR DNA..EXCEPT:
Papilloma Polyoma Hepadna
38
The only DNA virus that do not have an icosahedral symmetry
Poxvirus - complex
39
The ONLY DNA virus that replicated outside the nucleus
Poxvirus - because it cannot penetrate the nuclear membrane
40
Parvovirus are transmitted via
Respiratory drolets | Transplacental
41
Chronic B19 infection in immuodeficient patients can cause
Pancytopenia
42
The only virus with pentofiber
Adenovirus
43
Adenovirus infection in the GUT
Hemorrhagic cystitis
44
Parvovirus B19 histopath finding
Cowdry type B intranuclear inclusions
45
Naked virus with ds circular DNA, icosahedral nucleocapsid, infects squamous cells and induce formation of cytoplasmic vacuoles (koilocytes)
Human papilloma virus | Papovaviridae
46
HPV: encode proteins that inactivate tumor suppresor genes
Gene E6 and E7
47
HPV of skin and plantar warts
HPV 1-4
48
HPV in condylomata accuminata, respiratory tract papillomas; most common viral STD
HPV 6 and 11
49
HPV in carcinomas of the cervix, penis and anus
HPV 16, 18, 31 and 33
50
HPV treatment for genital, skin and plantar warts
Genital warts: podiohyllin Skin warts: liquid nitrogen Plantar warts: salicylic acid
51
2 types of viral symmetry
Spherical/ icosahedral | Helical
52
This drug is an immune disease modifier approved to treat actinic keratosis, superficial basal cell carcinoma and condylomata accuminata
Imiquimod
53
HSV 1&2 site of latency
HSV 1: trigeminal ganglia | HSV 2: lumbosacral ganglia
54
Large, pink to purple intranuclear inclusions which can be found in adenoviruses and herpes sinolex viruses
Cowdry type A inclusions
55
Tzanck smear: multinucleated giant cells
HSV
56
Tx HSV that can shorten duration of lesions, reduce extent of shedding with no effect on the latent state
Acyclovir
57
Dewdrop on rose petal appearance incubation period
Varicella 14-21 days
58
Ramsay Hunt Syndrome involves which ganglion and cranial nerve
Geniculate ganglion | Facial nerve - paralysis
59
Culture medium of CMV
Shell tubes
60
Most common cause of congenital abnormalities especially in the 1st trimester
CMV | Congenital CMV infection
61
Microcephaly, seizures, deafness, jaundice, blue berry muffin baby
Congenital CMV infection
62
DOC for CMV
Ganciclovir
63
Patient presents with fever, sore throat, lymphadenopathy and splenomegaly. Athlete is made to stop sports due to a rare but possible complication of
Splenic rupture Infectious mononucleosis/ kissing disease CMV
64
African man with unilateral facial asymmetry
Burkitt's lymphoma | CMV
65
Associated with Kaposi's sarcoma manifesting with dark purple flat to nodular skin lesions appearing at multiple sites
Human Herpesvirus-8 | Tx: surgery, radiation
66
What is the brick-shaped poxvirus with linear dsDNA showing what intracytoplasmic eosinophilic inclusions?
Variola virus Smallpox Guarnieri bodies
67
Intracytoplasmic eosinophilic inclusions in molluscum contagiosun
Henderson-peterson bodies
68
Tx of molluscum
Cidofivir
69
``` Interpret: HBsAg positive Anti-HBs negative Anti-HBc negative HBeAg positive ```
Incubation period
70
``` Interpret: HBsAg positive Anti-HBs negative Anti-HBc positive IgG HBeAg negative ```
Chronic carrier
71
``` Interpret: HBsAg negative Anti-HBs positive Anti-HBc negative HBeAg negative ```
Vaccinated
72
``` Interpret: HBsAg positive Anti-HBs negative Anti-HBc positive IgM HBeAg positive ```
Acute infection
73
``` Interpret: HBsAg negative Anti-HBs negative Anti-HBc positive IgM HBeAg negative ```
Window period
74
``` Interpret: HBsAg negative Anti-HBs negative Anti-HBc positive IgG HBeAg positive ```
Chronic active
75
``` Interpret: HBsAg negative Anti-HBs negative Anti-HBc positive IgM HBeAg negative ```
Complete recovery
76
HepB infection is associated with which autoimmune vasculitides
Polyarteritis nodosa
77
HepB treatment
Interferon- alpha | Lamivudin
78
All RNA viruses have single-stranded RNA except
Reovirus and Rotavirus
79
All RNA viruses replicate in the cytoplasm except
Influenza | Retrovirus
80
All Picornaviridae viruses are transmitted via oro-fecal except
Rhinovirus

Microbiology II (4 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions