Virology & Nematodes Flashcards
(115 cards)
0
Q
Naked RNA viruses (3)
A
Calici
Picorna
Reo
1
Q
Only virus that does not acquire their envelope from the host plasma membrane
A
Herpesvirus (from nuclear membrane)
2
Q
Naked DNA virus (4)
A
Parvovirus
Adeno
Papilloma
Polyoma
3
Q
Only diploid virus
A
Retrovirus (all others are haploid)
4
Q
RNA Viruses with segmented genome
A
Bunyavirus
Orthomyxovirus (influenza)
Arenavirus
Reovirus
B-O-A-R
5
Q
Negative strand RNA viruses (6)
A
Arena Bunya Paramyxovirus Orthomyxo Filo Rhabdo
6
Q
Only live attenuated vaccine that may be given to HIV-positive patients
A
MMR
7
Q
DNA viruses (7)
A
Hepadna Herpes Adeno Pox Parvovirus Polyoma Papilloma
8
Q
Only single stranded DNA virus
A
Parvovirus
9
Q
Only viruses with non-linear DNA (3)
A
Papilloma
Polyoma
Hepadna
10
Q
Only non-icosahedral DNA virus
A
Poxvirus
11
Q
Only DNA virus that does not replicate in the nucleus
A
Poxvirus
12
Q
Fifth disease (erythema infectiousum)
A
Parvovirus B19
13
Q
Complication of chronic B19 infection
A
Pancytopenia
14
Q
Only virus with fibers.
What are the fibers called?
A
Adenovirus
Penton fibers
15
Q
Cowdry type B intranuclear inclusions (2)
A
Adenovirus
Polio virus
16
Q
Infected squamous cells with formation of cytoplasmic vacuoles
A
Koilocytes
17
Q
HPV 1 to 4 cause:
A
Skin and plantar warts
18
Q
Most common viral STD
A
anogenital warts (condylomata acuminata) from HPV 6 and 11
19
Q
Cancerous HPV strains
A
HPV 16, 18, 31, 33
20
Q
Types of cancer caused by HPV 16, 18, 31, 33 (4)
A
Cervix
Penis
Anus
Vulvar
21
Q
Disease caused by JC polyoma virus in patients with AIDS
A
Progressive multifocal leukoencephaly (PML)
22
Q
Enveloped DNA viruses (6)
A
HSV 1, HSV 2, VZV, EBV, CMV, HHV 8
23
Q
DOC for herpes simplex virus
A
Acyclovir
24
Site of latency: HSV 1
Trigeminal ganglia
25
Site of latency: HSV 2
Lumbosacral ganglia
26
Cowdry type A intranuclear inclusions
Herpes simplex virus
27
Tzanck smear
Herpes simplex virus
28
Type of encephalitis caused by HSV 1
Temporal lobe encephalitis
29
Type of encephalitis caused by Japanese B
Thalamic encephalitis
30
Blueberry muffin syndromes
Congenital rubella
Congenital CMV
Disseminated neuroblastoma
31
Dewdrop on a rose petal appearance
Varicella rash (vesicular centrifugal)
32
Complication of aspirin use for pediatric patients
Reye's syndrome
33
Involvement of gene ulster ganglion causing facial nerve paralysis in herpes zoster infection
Ramsay hunt syndrome
34
Cultured in shell tubes
Cytomegalovirus
35
Cultured in germ tubes
Candida
36
Giant cells with owl's eye nuclear inclusions
Cytomegalovirus
37
Most common cause of congenital abnormalities
Congenital CMV infection
38
DOC of CMV
Gancyclovir
| CMV is largely resistant to acyclovir
39
Most common cause of blindness in HIV patients
CMV retinitis
40
Kissing disease
Epstein-Barr virus
41
Burkitt's lymphoma and nasopharyngeal carcinoma
Epstein-Barr virus
42
AIDS defining lesion
Kaposi's sarcoma
43
Causative viral infection of Kaposi's sarcoma
HHV-8
44
Intracytoplasmic eosinophilic inclusions seen in smallpox
Guarnieri bodies
45
Intracytoplasmic eosinophilic inclusions seen in Molluscum contagiosum
Henderson-Peterson bodies
46
DOC Molluscum contagiosum
Cifodovir
47
Only DNA virus that produces DNA via reverse transcription (mRNA template)
Hepatitis B infection
48
Complications of hepatitis B infection on the liver (3)
Hepatocellular carcinoma
Hepatorenal syndrome
Hepatopulmonary syndrome
49
DOC Hepatitis B infection
Interferon-alpha
| Lamivudine (anti-retroviral)
50
Only double stranded RNA virus
Rotavirus (type of reovirus)
| Reovirus
51
Only RNA viruses replicate in the cytoplasm except (2)
Influenza
| Retrovirus
52
Most common clinical form of polio virus infection
Abortive poliomyelitis
53
Enteroviruses (3)
Coxsackie
Poliovirus
Echovirus
54
MCC of viral induced myocarditis & pericarditis
Coxsackie B virus
55
MCC of aseptic meningitis
Enteroviruses (esp Coxscakie virus)
56
MCC common cold
Rhinovirus
| 2nd Coronavirus
57
Most important test for Hepatitis A infection
Anti-HAV IgM
58
Another name for hepatitis A virus
Enteroviruses 72
59
Which hepatitis type causes high mortality in pregnant women?
Hepatitis E
60
MCC NON-bacterial diarrhea in adults
Norwalk virus (Norvirus)
61
MCC childhood diarrhea
Rotavirus
62
Major antigens of influenza virus (2)
Hemagglutinin (H) & Neuraminidase (N)
63
Type of influenza that causes worldwide epidemics/pandemics
Influenza A
64
Major changes based in the reassortment of segments of the RNA genome; causes pandemics
Antigenic shifts
65
Minor changes based on mutations in the RNA genome
Antigenic drifts
66
DOC Influenza virus
Oseltamivir or zanamivir
67
Warthin-Finkeldy bodies (mutlinucleated giant cells)
Measles virus
68
Pathognomonic sign if measles infection
Koplik's spots
69
Most feared complication of measles
Subacute Sclerosing Panencephalitis (SSPE) aka Damson disease
70
DOC Respiratory Syncitial virus (if necessary)
Ribavirin
71
Steeple sign
Laryngotracheobronchitis (croup)
72
Cause of laryngotracheobronchitis (croup)
Parainfluenza virus 1 & 2
73
DOC Croup
Racemic epinephrine
74
Bullet shaped enveloped virus
Rabies virus (rhabdoviridae)
75
Negri bodies
Rabies virus
76
Receptor where the Coronavirus binds to causing severe acute respiratory syndrome (SARS)
ACE-2 receptors
77
Characteristic fever in dengue virus infection
Breakbone fever
78
Type of fluid accumulation experienced in dengue fever
3rd space loss: RIGHT-sided pleural effusion
79
Most prevalent blood-borne pathogen
Hepatitis C virus
80
Most common indication for liver transplant
Hepatitis C infection leading to severe cirrhosis
81
DOC Chronic hepatitis C
Peginterferon & ribavirin
82
DOC Acute hepatitis C
Interferon
83
Cause if immune-complex polyarthritis in adults
Rubella virus
84
Associated abnormalities in congenital rubella syndrome (5)
```
PDA
Congenital cataracts
Sensorineural deafness
Mental retardation
Blueberry muffin syndrome
```
85
Only RNA virus with reverse transcriptase
Retroviridae
86
Part of the HIV virus that is used for diagnosis/lab identification
Major capsid protein (p24)
87
Part of the HIV virus that directs the entry of double-stranded DNA into the nucleus; important for cell assembly
Outer membrane protein (p17)
88
Components of the gag gene in the HIV virus; structural proteins
p24, p7 (nucelocapsid)
| p17 (matrix)
89
Protein component of the pol gene in HIV; for enzymes
Reverse transcriptase (transcribes RNA into DNA)
Protease (cleaves precursor polypeptides)
Integrase (viral DNA + host cell DNA)
90
Responsible for the mutagenic property of HIV
Integrase
91
Proteins part of the env gene of HIV; for the envelope
gp120 (attaches to CD4; rapid change in antigenicity)
| gp41 (fuses with host cell)
92
Used for the definitive diagnosis of HIV
Western blot
93
Most common AIDS defining illness
Pneumocystis jiroveci/carinii pneumonia (PCP)
94
Most common cause of death in AIDS
M. Tuberculosis (disseminated tuberculosis)
95
Malignant T cells with flower-shaped nucleus
Human T-cell Lymphotropic Virus (HTLV)
96
MCC epidemic encephalitis
Japanese B virus
97
Diagnostic test for Enterobious vermicularis
Graham's scotch tape technique
98
DOC Enterobius vermicularis
Pyrantel pamoate
99
Diagnostic test for Strongyloides stercoralis
Harada-Mori culture
100
Only nematode whose life cycle involves a migratory bird
Capillaria philippinensis
101
Peanut-shaped egg with flattened bipolar plugs
Capillaria philippinensis
102
Most debilitating nematode infection
Wucheria & Brugia
103
Farmer from abaca plantation
Wucheria & Brugia
104
Mosquito vector of Brugia malayi
Mansonia
105
Mosquito vector of Wucheria bancrofti
Culex, Aedes, Anopheles
106
Infective stage of Wucheria & Brugia
3rd stage larvae
107
Meyers-Kouvenaar bodies (tropical eosinophilic granulomas)
Wucheria & Brugia
108
Elephantiasis
Brugia malayi
109
Areas with high incidence of Wucheria bancrofti
Sorsogon, Samar, Leyte, Palawan
| Camarines, Albay, Mindoro, Marinduque, Romblon, all of Mindanao
110
High incidence of Brugia malayi
Eastern Samar, Agusan del Sur, Palawan, Sulu
111
DOC for Wucheria & Brugia (can also be used for diagnosis)
Diethylcarbamazine
112
MCC parasitic meningitis
Angiostrongylus cantonensis
113
Bedbugs
Cimex lenticularis
114
Ticks
Dermacentar (causing ascending paralysis)
