Virus

Question 1

All enveloped viruses acquire their envelope from plasma membrane except

Answer 1

Herpesviruses

Question 2

Naked viral genome infectivity
ssRNA (+)
ssRNA (-)
dsRNA
dsDNA

Answer 2

ssRNA (+)

dsDNA except poxviruses and HBV

Question 3

Segmented genome

Answer 3

Orthomyxovirus

Reovirus

Question 4

Decrease in acid production by infected, dying cells seen using

Answer 4

Phenol red

Question 5

Only live-attenuated vaccine that may be given to HIV-positive patients

Answer 5

MMR

Question 6

All DNA viruses have double-stranded DNA except

Answer 6

Parvovirus

Question 7

All DNA viruses have linear DNA except

Answer 7

Papilloma
Polyoma
Hepadna

Question 8

All DNA viruses are icosahedral except

Answer 8

Poxvirus

Question 9

All DNA viruses replicate to the nucleus except

Answer 9

Poxvirus

Question 10

Erythema infectiosum (fifth disease)

Answer 10

Parvovirus B19

Question 11

Only virus with fiber

Answer 11

Adenovirus

Question 12

Most common cause of viral conjunctivitis

Answer 12

Adenovirus

Question 13

HPV strains causing genital warts

Answer 13

6 and 11

Question 14

HPV strains causing carcinomas

Answer 14

16, 18, 31 and 33

Question 15

Progressive multifocal leukoencephalopathy (PML)

Answer 15

JC polyoma virus

Question 16

Hemorrhagic cystitis and nephropathy

Answer 16

BK polyoma virus

Question 17

Visualization of HSV

Answer 17

Tzanck smear

Question 18

Drug of choice for HSV

Answer 18

Aciclovir

No effect on latent state!

Question 19

Ramsay Hunt syndrome

Answer 19

Herpes zoster oticus

Question 20

Infectious mononucleosis

Positive heterophil test

Answer 20

EBV

Question 21

Infectious mononucleosis

Negative heterophil test

Answer 21

CMV

Toxoplasma

Question 22

Drug of choice for CMV retinitis

Answer 22

Foscarnet

Question 23

Malignancies caused by Epstein-Barr virus

Answer 23

Burkitt’s lympomma

Nasopharyngeal carcinoma

Question 24

Drug of choice for molluscum contangiosum

Answer 24

Cifodovir

Question 25

Hepatitis B is associated with what autoimmune vasculitides

Answer 25

Polyarteritis nodosa

Question 26

Drug of choice for hepatitis B

Answer 26

Interferon-alpha and lamivudin

Question 27

All RNA viruses have single-stranded DNA except

Answer 27

Reovirus | Rotavirus

Question 28

All DNA viruses replicate in the cytoplasm except

Answer 28

Influenza | Retrovirus

Question 29

Most common clinical form of polio

Answer 29

Abortive poliomyelitis

Question 30

Most common cause of myocarditis and pericarditis

Answer 30

Coxsackie virus

Question 31

Echovirus

Answer 31

enteric cytopathic human orphan

Question 32

Herpangina is caused by

Answer 32

Coxsackie virus

Question 33

Most important test for hepatitis A

Answer 33

Anti-HAV IgM

Question 34

Most common cause of nonbacterial diarrhea in adults

Answer 34

Norvovirus

Question 35

Most common cause of childhood diarrhea

Answer 35

Rotavirus

Question 36

Most common cause of respiratory tract infections

Answer 36

Influenza

Question 37

Influenza: binds to cell surface receptor

Answer 37

Hemagglutinin

Question 38

Influenza: cleaves sialic acid

Answer 38

Neuraminidase

Question 39

Source of influenza B virus

Answer 39

Humans only

Question 40

Measles: multinucleated giant cells

Answer 40

Warthin-Finkedely bodies

Question 41

Damson disease

Answer 41

Subacute sclerosing panencephalitis

Question 42

Most improtant cause of pneumonia and brohchiolitis in infants

Answer 42

Respiratory syncytial virus

Question 43

Drug of choice for respiratory syncytial virus

Answer 43

Ribavirin

Question 44

Rabies: touching or feeding animals, licks on skin

Answer 44

No treatment

Question 45

Rabies: nibbling of uncovered skin

Answer 45

Vaccine

Question 46

Rabies: minor scratches or abrasions without bleeding

Answer 46

Vaccine

Question 47

Rabies: licks on unbroken skin

Answer 47

Vaccine

Question 48

Rabies: transdermal bites or scratches

Answer 48

Vaccine + immunoglobulin

Question 49

Rabies: Contamination of mucous membranes with saliva from licks

Answer 49

Vaccine + immunoglobulin

Question 50

Coronavirus binds to

Answer 50

ACE-2 receptor

Question 51

Most virulent of dengue serotypes

Answer 51

DEN 2

Question 52

Most prevalent blood-borne antigen

Answer 52

Hepatitis C virus

Question 53

Main cause of essential mixed cryoglobulinemia

Answer 53

Hepatitis C

Question 54

HIV: transmembrane/fusion protein

Answer 54

gp41

Question 55

HIV: surface/attachment protein

Answer 55

gp120

Question 56

HIV: major capsid protein

Answer 56

p24

Question 57

HIV: nucleoprotein

Answer 57

p7

Question 58

HIV: outer matrix protein

Answer 58

p17

Question 59

HIV: gene coding for reverse transcriptase, protease, integrase

Answer 59

pol

Question 60

HIV: gene responsible fro decreasing CD4 and class I MHC proteins

Answer 60

nef

Question 61

Most common AIDS-defining illness

Answer 61

PCP

Question 62

HIV: presumptive diagnosis

Answer 62

ELISA

Question 63

HIV: definitive diagnosis

Answer 63

Western blot

Question 64

Perinatal prevention of HIV

Answer 64

Zidovudine

Question 65

True or false: all helical viruses are naked

Answer 65

Enveloped

Question 66

All viruses are haploid except

Answer 66

Retroviruses

Question 67

Segmented viruses

Answer 67

Orthomyxovirus | Reovirus

Question 68

Henderson-peterson bodies

Answer 68

Molluscum contagiosum

Question 69

Guarnieri bodies

Answer 69

Molluscum contagiosum

Question 70

Treatment for molluscum contagiosum

Answer 70

Cifodovir

Question 71

Most common cause of aseptic meningitis

Answer 71

Coxsackie virus

Question 72

True or false: rhinoviruses are acid stable

Answer 72

Acid labile

Question 73

True or false: measles virus has hemagglutinin and neuraminidase

Answer 73

Hemagglutinin only

Question 74

True or false: RSV has hemagglutinin and neuraminidase

Answer 74

None. Fusion protein

Question 75

Treatment for RSV infection

Answer 75

Ribavirin

Question 76

Viral arthritis

Answer 76

Parvovirus B19

Question 77

Vaccine frim reassorted bovine and human viruses

Answer 77

Rotavirus