VIRUS Flashcards
(181 cards)
1
Q
dna virus with single stranded DNA
A
Parvo
2
Q
all dna virus are icosahedral except
A
pox virus
3
Q
5th disase
A
parvo
4
Q
parvo in first trimester
A
fetal death
5
Q
parvo 2nd trimester
A
hydrops fetalis
6
Q
can cause sicle cell anemia, spherocytosis
A
parvo
7
Q
smallest dna virus
A
parvo
8
Q
cowdry tpe b intranuclear basophil inclusions
A
adenovirus
9
Q
koilocytes
A
hpv
10
Q
hpv: promotes dna replication
A
e1 and e2
11
Q
hpv: inhibits p53
A
e6
12
Q
hpv: inh rb
A
e7
13
Q
hpv causing cancer
A
16, 18, 31, 33
14
Q
hpv causing plantar warts
A
1, 2, 4, 7
15
Q
tx genital warts
A
podophyllin
16
Q
tx skin warts
A
liquid nitrogen
17
Q
tx plantar warts
A
salicylic acid
18
Q
progressive multifocal leukoencephalopathy
targets oligodendrocytes
A
JC polyoma virus
19
Q
hemorrhagic cystitis and nephropathy in patients with solid organ kidney and bone marrow transplants
A
BK Polyoma
20
Q
decoy cells
A
BK polyoma
21
Q
site of latency in HSV 2
A
Lumbosacral ganglia
22
Q
site of latency in HSV 1
A
Trigeminal ganglia
23
Q
genital herpes
neonatal herpes
aseptic meningitis
A
HSV 2
24
Q
COWDRY TYPE a inclusions in DNA virus eosinophilic intranuclear
A
HSV VZV
25
Part of the brain affected by syphylis
temporal
26
becomes latent in dorsal root ganglia
VZV
27
Varicella incubation period
14-21 days
28
mc complication of vzv
post herpetic neuralgia
29
reactivation of vzv in GENICULATE GANGLION
Ramsay Hunt syndrome
30
tx of ramsay hunt syndrome
valacyclovir
| prednisone
31
vzv in 6-12 wks AOG
limb development
32
vzv in 16-20 wks
eyes and brain
33
active vaccine post vzv exposure given w/in
5 days
34
Ig may be given post vzv exposure within
96 hrs
35
owl's eye inclusions
CMV
36
MC infectious cause of congenital anomalies
cmv
37
mc intrauterine viral infections
cmv
38
periventricular calcifications
cmv
39
AIDS retinitis
CMV
40
DOC CMV
ganciclovir
41
prevention of CMV in solid organ transplant patients
valganciclovir
42
infects B lymphocytes
EBV
43
```
Assoc w:
burkitts
nasopharyngeal CA
Hairy leukoplakia
B cell lymphoma
```
EBV
44
Downey cells
EBV
45
6TH disease
roseola
46
other name for roseola
exanthem subitum
47
erythematous papules on soft palate and base of uvula in roseola
nagayama spots
48
MC AIDS related malignancy
kaposi sarcoma
49
malignancy of vascular endothelial cells
vascular proliferation
kaposi
50
only dna virus that replicates in the cytoplasm
pox
51
largest DNA virus
pox
52
only DNA virus that is complex
pox
53
brick shaped pox virus
variola
54
vesicles with same stage of development
small pox
55
IP of small pox
7-14 days
56
guarnieri bodies
variola
57
flesh dome shaped with central umbilication
molluscum contangiosum
58
henderson patterson intracytoplasmic bodies
molluscum contangiosum
59
tx of molluscum contangiosum
cidofovir
60
incomplete circular double stranded dna
hepa B
61
Produce DNA by reverse transcriptase
hepa B
62
Aplastic anemia
MPGN
PAN
Hep B
63
Granular ground glass appearance of the liver in biopsy
hep b
64
councilman body
hepa B
65
Dane particles
hepa B
66
Complete infectious form of hepatitis
dane particles
67
best predictor of chronicity of hepa b
age at the time of infection
68
treatment hepa B
LITE
Lamivudine
interferon alfa
tenofovir
entecavir
69
RNA viruses replicate in cytoplasm
influenza and retro
70
replicates in anterior motor neurons in the anterior horn of spinal cord
polio
71
mc clinical form of polio
abortive poliomyelitis
72
polio with aseptic meningitis
non paralytic poliomyelitis
73
inclusion bodies of polio
cowdry type B
74
CLASSIFICATION BASED ON pathology in mice
coxsackie
75
herpangina - vesicular pharyngitis
coxsackie A
76
HFMD
coxsackie A
77
MCC of aseptic meningitis
coxsackie B
78
Pleurodynia (Bornholm disease, devil's grip
coxsackie B - pain due to infection of intercostal muscles
79
affect nose and conjunctiva
rhino
80
mcc of common cold
rhino
81
hepa a has how many serotype
1
82
patchy necrosis in the liver
hepa E
83
Most important cause of epidemic viral gastroenteritis
norwalk
84
segmented double stranded RNA virus
Rota
85
white stool diarrhea
rota
86
1st dose of rota:
6 weeks
87
last dose of rota
not later than 32
88
segmented RNA virus
```
BOAR
bunya
ortho
arena
reo
```
89
antigenic shift
pandemic or epidemic
90
based on reassortment
antigenic shift
91
minor change in mutation
antigenic drift
92
most important antigen in influenza
hemaglutinin
93
causes outbreaks of flu
influenza B
94
Mild respi infection
influenza C
95
Influenza A has __ hemaglutinin and ___ neuraminidase
16, 9
96
no animal souce; no shift and drift
influenza B
97
DOC INFLUENZA
Oseltamivir
98
infects reticuloendothelial cells
measles
99
IP measles
10-14 days
100
1st disease
measles
101
Post exposure measles: Ig___ active ;vaccine___
within 6 days; w/in 3 days
102
mcc of aseptic meningitis
Mumps
coxsackie
echo
103
fusion proteins causing syncitia
RSV
104
Most impt cause of pneumonia and bronchiolitis in infants
RSV
105
Prevents pneumonia caused by RSV
palivizumab
106
LTB/ Croup
parainfluenza
107
tx of parainfluenza
racemic epi
108
gold standard in detection of rabies
IFAT
109
Longest viruses
ebola
110
thread like viruses
ebola
111
natural hosts of ebola
fruit bat
112
what are the target of ebola
endothelial cells
phagocytes
hepatocytes
113
IP of ebola
2-21 days
114
ebola named after
river in Zaire
115
prominet club shaped spikes forimg a halo/ corona
corona virus
116
causes SARS and MERS-COV
Corona
117
serotypes of corona
229E and OC43
118
Interstitial groundglass infiltrates in xray
SARS
119
SARS IP
2-10 mean 5
120
Receptor of SARS
ACE-2
121
Receptor of MERS COV
CD-26
122
DENGUE confirmation
viral culture
123
hep c has how many serotypes
6
124
confirmatory test hepa C
RIBA
125
replication of hep c in the liver is enhanced by
miR-122
126
IP of HEP C
8 wks
127
main cause of essential mixed cryoglobulinemia
HCV
128
Mode of transmission of Zika
aedes
| sexual vertical
129
zika IP
2-7 days
130
complications of Zika
microcephaly
| GBS
131
Reservoir of yellow fever
monkey
| human
132
jaundice and fever
yellow fever
133
black vomit
yellow fever
134
councilman bodies in RNA virus
yellow fever
135
arboviruses
yellow fever
west nile
toga, flavi, bunya
136
reservoir west nile
wild birds
137
bird-mosquito-man cycle
west nile
138
vector in West nile
Culex
139
fever then encephalitis with or without meningitis
West Nile
140
vector of Japansese enceph
culex
141
MCC of epidemic encephalitis
japanese enceph
142
vector in Jap Enceph
culex summarosus
143
thalamic infarcts on CT scan
jap enceph
144
JE vaccine
0.5 ml sq 12 months above
145
3 day measls
rubella
146
tubella has how many serotypes
1
147
IP Rubella
14-21 days
148
petechiae on palate in rubella
forchheimer spots
149
most characteristic feature in rubella
lymphadenopathy
150
pathogenesis congenital rubella
chromosomal breakage and inhibition of mitosis
151
attachment to CD4 protein
gp 120
152
fusion with host cell
gp41
153
p24, p7
nucleocapsid
154
p17
matrix
155
activation of transcription of viral genes
tat
156
transport of late mrna from nucleus to cytoplasm
rev
157
induce death of uninfected cutotoxic t cell
nef
158
enhances infectivity by inhibiting APO BEC3G
vif
159
transport vital core from cytoplasm to nucleus
vpr
160
enhances virion release
vpu
161
coreceptor of cd4 in early infection
CCR5 on macrophage
162
coreceptor of cd4 in late infection
CXCR4 T cells
163
rapid viral replication in HIV
Window period phase 1
164
peak of viral load
seroconversion phase 2
165
asymptomatic
latent phase 3
166
cd4 500-200
early symptomatic phase 4
167
cd4 less than 200
AIDS
168
Less than 200 CD4
PCP pneumonia
toxoplasmosis
coccicoidomycosis
169
less than 50 CD4
M. avium
H. capsulatum
CMV retinitis
170
presumptive diagnosis in HIV
ELISA - p24 protein
171
definitive diagnosis HIV
Western blot
172
tx of HIV
2 NRTI- Zidovudine, LAMIVUDINE
| Protease inh- indinavir
173
hepatitis
hepatocyte swelling, monocye infiltration
hepa A
174
Groundglass appearance, granular
hepa
b and D
175
No carrier state
| hepa___
a and e
176
lymphoild aggregates with focal areas of macrovesicular steatosis___
C
177
RNA Deltavirus
Hepa D
178
14 DAY MEASLES
rubeola
179
second disease
scarlet
180
fourth disease
filatow-duke's disease
SSSS
Ritters disease
181
sudden rash
roseola
