Viruses Flashcards
What is a Virus?
An infectious agent consisting of genetic material (DNA or RNA) inside a protein coat.
What is a Capsid?
A protein shell that encloses the viral genome.
What is an Envelope?
Modified piece of the host of the host cell membrane.
What is a Naked Virus?
A virus consisting only of a nucleocapsid without an envelope.
What are Spikes?
Glycoproteins on a virus surface that help it attach to host cells.
What is a Virion?
A fully formed virus capable of infecting a host cell.
What is a Helical Capsid?
Capsid with a spiral structure surrounding the viral genome.
What is an Icosahedral Capsid?
Capsid with a 3D, 20-sided shape with evenly spaced corners.
What is a Complex Capsid?
A virus structure that does not fit helical or icosahedral shapes.
What is Positive Sense RNA?
Single-stranded RNA ready for immediate translation.
What is Negative Sense RNA?
RNA that must be converted into a readable form before translation.
What are Polymerases?
Enzymes that synthesize DNA and RNA in viral replication.
What is Reverse Transcriptase?
Enzyme that synthesizes DNA from an RNA template (e.g., HIV).
What is the General Virus Life Cycle?
Includes adsorption, penetration, uncoating, synthesis, assembly, and release.
What is Specific Attachment?
Virus enters a host cell via endocytosis.
What is Irreversible Attachment?
Viral membrane fuses with the host membrane to release nucleic acid.
What are Cytopathic Effects?
Virus-induced cellular damage altering the cell’s shape or function.
What is an Inclusion Body?
Compact mass of virus or damaged organelles inside a host cell.
What are Syncytia?
Fusion of multiple host cells into one large multinucleated cell.
What is a Provirus?
Viral DNA that is incorporated into the host genome.
What is a Chronic Latent State?
A virus that remains dormant and reactivates periodically.
What is an Oncogenic Virus?
Virus that can cause cancer by altering host cell growth regulation.
What is Transformation?
Process where viral genes induce uncontrolled cell growth, increasing cancer risk.
What is the Lytic Cycle?
Virus replication that results in host cell destruction.