Viruses Flashcards

1
Q

Poliovirus

A
  • Picornavirus (single, linear RNA)
  • nonenveloped
  • polio
  • Salk and Sabin vaccine
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2
Q

Echovirus

A
  • Picornavirus (single, linear RNA)
  • nonenveloped
  • aseptic meningitis
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3
Q

Rhinovirus

A
  • Picornavirus (single, linear RNA)
  • nonenveloped
  • common cold
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4
Q

Coxsackie A virus

A
  • Picornavirus (single, linear RNA)
  • nonenveloped
  • herpangina
  • hand-foot-mouth disease
  • acute lymphonodular pharyngitis
  • aseptic meningitis
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5
Q

Coxsackie B virus

A
  • Picornavirus (single, linear RNA)
  • nonenveloped
  • pleurodynia
  • myocarditis
  • pericarditis
  • aseptic meningitis
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6
Q

HAV

A
  • Picornavirus (single, linear RNA)
  • nonenveloped
  • hepatitis A
  • vaccine
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7
Q

Norwalk virus

A
  • Calicivirus (single, linear RNA)
  • nonenveloped
  • gastroenteritis (adults)
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8
Q

HEV

A
  • Hepevirus (single, linear RNA)
  • nonenveloped
  • hepatitis E
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9
Q

Rotavirus

A
  • Reovirus (double, linear RNA)
  • nonenveloped
  • gastroenteritis (infants)
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10
Q

Coltivirus

A
  • Reovirus (double, linear RNA)
  • nonenveloped
  • arbovirus: the only transmitted by ticks
  • Colorado tick fever
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11
Q

HDV

A
  • Deltavirus (single, circular RNA)
  • enveloped
  • hepatitis D (alfa-interferon)
  • vaccine
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12
Q

Japanese virus

A
  • Flavivirus (single, linear RNA)
  • enveloped
  • encephalitis
  • vaccine
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13
Q

Yellow fever virus

A
  • Flavivirus (single, linear RNA)
  • enveloped
  • arbovirus
  • yellow fever
  • vaccine
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14
Q

West Nile virus

A
  • Flavivirus (single, linear RNA)
  • enveloped
  • arbovirus
  • encephalitis
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15
Q

Dengue virus

A
  • Flavivirus (single, linear RNA)
  • enveloped
  • arbovirus
  • dengue fever
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16
Q

HCV

A
  • Flavivirus (single, linear RNA)
  • enveloped
  • hepatitis C (alfa-interferon, ribavirin)
  • ass. with hepatocellular carcinoma
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17
Q

Rubella virus

A
  • Togavirus (single, linear RNA)
  • enveloped
  • rubella (German, “3-day” measles, trunkal rash, teratogen)
  • vaccine
18
Q

Eastern/Western virus

A
  • Togavirus (single, linear RNA)
  • enveloped
  • arbovirus
  • encephalitis
19
Q

Influenza viruses

A
  • Orthomyxovirus (single, linear RNA)
  • enveloped
  • influenza
  • ass. with Reye’s Syndrome
  • vaccine
  • amantidine, rimantidine, zanamivir, oseltamivir
20
Q

HTLV

A
  • Retrovirus (single, linear RNA)
  • enveloped
  • diploid
  • adult T-cell leukemia / lymphoma
  • chronic progressive myelopathy
21
Q

HIV

A
  • Retrovirus (single, linear RNA)
  • enveloped
  • diploid
  • infects CD4 Th cells
  • diagnosis confirmed by Western Blot
  • AIDS
  • zidovudine (AZT), lamivudine, stavudine, indinavir, ritonavir
22
Q

Measles virus

A
  • Paramyxovirus (single, linear RNA)
  • enveloped
  • measles (rubeola): Koplik’s spots
  • vaccine
23
Q

Mumps virus

A
  • Paramyxovirus (single, linear RNA)
  • enveloped
  • mumps (parotitis, orchitis, deafness)
  • vaccine
24
Q

RSV

A
  • Paramyxovirus (single, linear RNA)
  • enveloped
  • infants only
  • bronchiolitis
  • pneumonia
  • ribavirin
25
Parainfluenza viruses
- Paramyxovirus (single, linear RNA) - enveloped - croup - bronchiolitis - common cold
26
Rabies virus
- Rhabdobirus (single, linear RNA) - enveloped - rabies - vaccine
27
Ebola virus
- Filovirus (single, linear RNA) - enveloped - ebola, hemorrhagic fever
28
Coronavirus
- Coronavirus (linear, single RNA) - enveloped - common cold - SARS
29
Hantavirus
= Sin Nombre virus - Bunyavirus (single, circular RNA) - enveloped - hantavirus hemorrhagic fever
30
B19 virus
- Parvovirus (single, linear DNA) - nonenveloped - smallest DNA virus - aplastic anemia - ass. sickle cell disease - erythema infectiosum (5th disease) - fetal infections
31
HPV
- Papillomavirus (double, circular DNA) - nonenveloped - papillomas (warts) - condylomata acuminatum (genital warts) - verruca vulgaris - cervical cancer - podophyllin, alfa-interferon, cidofovir - vaccine
32
JC virus
- Polyomavirus (double, circular DNA) - nonenveloped - progressive multifocal leukoencephalopathy - ass. with HIV
33
Adenovirus
- Adenovirus (double, linear DNA) - nonenveloped - pharyngitis - conjunctivitis - pneumonia - common cold - vaccine
34
HBV
- Hepadnavirus (double, circular DNA) - enveloped - reverse transcriptase - hepatitis B - ass. with hepatocellular carcinoma - alfa-interferon, lamivudine - vaccine
35
Variola virus
- Poxvirus (double, linear) - enveloped - largest DNA virus - smallpox (eradicated) - vaccine
36
MCV
- Poxvirus (double, linear DNA) - enveloped - largest DNA virus - molluscum contaginosum
37
HSV-1
- Herpesvirus (double, linear DNA) - enveloped (host nuclear membrane) - Tzank test - herpes labialis - keratoconjunctivitis - gingivostomatitis - reccurrent encephalitis - acyclovir, penciclovir, valacyclovir, famciclovir
38
HSV-2
- Herpesvirus (double, linear DNA) - enveloped (host nuclear membrane) - Tzank test - herpes genitalis - neonatal encephalitis - aseptic meningitis - acyclovir, penciclovir, valacyclovir, famciclovir
39
VZV
- Herpesvirus (double, linear DNA) - enveloped (host nuclear membrane) - Tzank test - varicella - ass. with Reye's syndrome - zoster = shingles - acyclovir, famciclovir, valacyclovir - vaccine
40
CMV
- Herpesvirus (double, linear DNA) - enveloped (host nuclear membrane) - congenital abnormalities (primary viral cause of mental retardation) - cytomegalic inclusion disease - ganciclovir, valganciclovir, foscarnet
41
EBV
- Herpesvirus (double, linear DNA) - enveloped (host nuclear membrane) - infectious mononucleosis (necrotizing pharyngitis, heterophile test for screening) - ass. with Burkitt's lymphoma - ass. with nasopharyngeal carcinoma - ass. with B-cell lymphoma - ass. with hairy leukoplakia - self-limiting 2-3 weeks
42
HHV-8
- Herpesvirus (double, linear DNA) - enveloped (host nuclear membrane) - Kaposi's sarcoma