Viruses Flashcards
1
Q
Poliovirus
A
- Picornavirus (single, linear RNA)
- nonenveloped
- polio
- Salk and Sabin vaccine
2
Q
Echovirus
A
- Picornavirus (single, linear RNA)
- nonenveloped
- aseptic meningitis
3
Q
Rhinovirus
A
- Picornavirus (single, linear RNA)
- nonenveloped
- common cold
4
Q
Coxsackie A virus
A
- Picornavirus (single, linear RNA)
- nonenveloped
- herpangina
- hand-foot-mouth disease
- acute lymphonodular pharyngitis
- aseptic meningitis
5
Q
Coxsackie B virus
A
- Picornavirus (single, linear RNA)
- nonenveloped
- pleurodynia
- myocarditis
- pericarditis
- aseptic meningitis
6
Q
HAV
A
- Picornavirus (single, linear RNA)
- nonenveloped
- hepatitis A
- vaccine
7
Q
Norwalk virus
A
- Calicivirus (single, linear RNA)
- nonenveloped
- gastroenteritis (adults)
8
Q
HEV
A
- Hepevirus (single, linear RNA)
- nonenveloped
- hepatitis E
9
Q
Rotavirus
A
- Reovirus (double, linear RNA)
- nonenveloped
- gastroenteritis (infants)
10
Q
Coltivirus
A
- Reovirus (double, linear RNA)
- nonenveloped
- arbovirus: the only transmitted by ticks
- Colorado tick fever
11
Q
HDV
A
- Deltavirus (single, circular RNA)
- enveloped
- hepatitis D (alfa-interferon)
- vaccine
12
Q
Japanese virus
A
- Flavivirus (single, linear RNA)
- enveloped
- encephalitis
- vaccine
13
Q
Yellow fever virus
A
- Flavivirus (single, linear RNA)
- enveloped
- arbovirus
- yellow fever
- vaccine
14
Q
West Nile virus
A
- Flavivirus (single, linear RNA)
- enveloped
- arbovirus
- encephalitis
15
Q
Dengue virus
A
- Flavivirus (single, linear RNA)
- enveloped
- arbovirus
- dengue fever
16
Q
HCV
A
- Flavivirus (single, linear RNA)
- enveloped
- hepatitis C (alfa-interferon, ribavirin)
- ass. with hepatocellular carcinoma
17
Q
Rubella virus
A
- Togavirus (single, linear RNA)
- enveloped
- rubella (German, “3-day” measles, trunkal rash, teratogen)
- vaccine
18
Q
Eastern/Western virus
A
- Togavirus (single, linear RNA)
- enveloped
- arbovirus
- encephalitis
19
Q
Influenza viruses
A
- Orthomyxovirus (single, linear RNA)
- enveloped
- influenza
- ass. with Reye’s Syndrome
- vaccine
- amantidine, rimantidine, zanamivir, oseltamivir
20
Q
HTLV
A
- Retrovirus (single, linear RNA)
- enveloped
- diploid
- adult T-cell leukemia / lymphoma
- chronic progressive myelopathy
21
Q
HIV
A
- Retrovirus (single, linear RNA)
- enveloped
- diploid
- infects CD4 Th cells
- diagnosis confirmed by Western Blot
- AIDS
- zidovudine (AZT), lamivudine, stavudine, indinavir, ritonavir
22
Q
Measles virus
A
- Paramyxovirus (single, linear RNA)
- enveloped
- measles (rubeola): Koplik’s spots
- vaccine
23
Q
Mumps virus
A
- Paramyxovirus (single, linear RNA)
- enveloped
- mumps (parotitis, orchitis, deafness)
- vaccine
24
Q
RSV
A
- Paramyxovirus (single, linear RNA)
- enveloped
- infants only
- bronchiolitis
- pneumonia
- ribavirin
25
Parainfluenza viruses
- Paramyxovirus (single, linear RNA)
- enveloped
- croup
- bronchiolitis
- common cold
26
Rabies virus
- Rhabdobirus (single, linear RNA)
- enveloped
- rabies
- vaccine
27
Ebola virus
- Filovirus (single, linear RNA)
- enveloped
- ebola, hemorrhagic fever
28
Coronavirus
- Coronavirus (linear, single RNA)
- enveloped
- common cold
- SARS
29
Hantavirus
= Sin Nombre virus
- Bunyavirus (single, circular RNA)
- enveloped
- hantavirus hemorrhagic fever
30
B19 virus
- Parvovirus (single, linear DNA)
- nonenveloped
- smallest DNA virus
- aplastic anemia
- ass. sickle cell disease
- erythema infectiosum (5th disease)
- fetal infections
31
HPV
- Papillomavirus (double, circular DNA)
- nonenveloped
- papillomas (warts)
- condylomata acuminatum (genital warts)
- verruca vulgaris
- cervical cancer
- podophyllin, alfa-interferon, cidofovir
- vaccine
32
JC virus
- Polyomavirus (double, circular DNA)
- nonenveloped
- progressive multifocal leukoencephalopathy
- ass. with HIV
33
Adenovirus
- Adenovirus (double, linear DNA)
- nonenveloped
- pharyngitis
- conjunctivitis
- pneumonia
- common cold
- vaccine
34
HBV
- Hepadnavirus (double, circular DNA)
- enveloped
- reverse transcriptase
- hepatitis B
- ass. with hepatocellular carcinoma
- alfa-interferon, lamivudine
- vaccine
35
Variola virus
- Poxvirus (double, linear)
- enveloped
- largest DNA virus
- smallpox (eradicated)
- vaccine
36
MCV
- Poxvirus (double, linear DNA)
- enveloped
- largest DNA virus
- molluscum contaginosum
37
HSV-1
- Herpesvirus (double, linear DNA)
- enveloped (host nuclear membrane)
- Tzank test
- herpes labialis
- keratoconjunctivitis
- gingivostomatitis
- reccurrent encephalitis
- acyclovir, penciclovir, valacyclovir, famciclovir
38
HSV-2
- Herpesvirus (double, linear DNA)
- enveloped (host nuclear membrane)
- Tzank test
- herpes genitalis
- neonatal encephalitis
- aseptic meningitis
- acyclovir, penciclovir, valacyclovir, famciclovir
39
VZV
- Herpesvirus (double, linear DNA)
- enveloped (host nuclear membrane)
- Tzank test
- varicella
- ass. with Reye's syndrome
- zoster = shingles
- acyclovir, famciclovir, valacyclovir
- vaccine
40
CMV
- Herpesvirus (double, linear DNA)
- enveloped (host nuclear membrane)
- congenital abnormalities (primary viral cause of mental retardation)
- cytomegalic inclusion disease
- ganciclovir, valganciclovir, foscarnet
41
EBV
- Herpesvirus (double, linear DNA)
- enveloped (host nuclear membrane)
- infectious mononucleosis (necrotizing pharyngitis, heterophile test for screening)
- ass. with Burkitt's lymphoma
- ass. with nasopharyngeal carcinoma
- ass. with B-cell lymphoma
- ass. with hairy leukoplakia
- self-limiting 2-3 weeks
42
HHV-8
- Herpesvirus (double, linear DNA)
- enveloped (host nuclear membrane)
- Kaposi's sarcoma