Visual System Flashcards

1
Q

where does the pathways subserving visual perception originate?

A

retina

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2
Q

where does the pathway of vision go from retina?

A

retina –> dorsal nucleus of lateral geniculate body of thalamus –> primary visual cortex (striate cortex, area 17, V1)

then to occipital, temporal and parietal association areas

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3
Q

where do the retinal ganglion cell axons pass via?

A

optic nerves, optic chiasma and optic tract

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4
Q

how many axons does the optic nerves have?

A

1 million myelinated axons

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5
Q

describe the optic chiasm

A

–Partial crossing of optic nerve fibres
-ganglion cell axons from nasal retina cross here
–Essential for binocular vision

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6
Q

describe the optic tract

A

–Curves around the rostral midbrain and ends in the lateral geniculate body of the thalamus

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7
Q

what is binocular and monocular crescents field?

A

binocular –>visual field viewed by both eyes
monocular crescents –> visual field viewed by only one eye

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8
Q

where does the left hemifield project to in the brain? and vice versa

A

left hemifield to right side of the brain –> the right LGN and right visual cortex (right hemifield to left side of brain

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9
Q

describe the upper half of the visual field (which fall on the bottom parts of the retina)

A

– processed by lateral LGN and visual cortex below the calcarine sulcus

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10
Q

describe the lower half of the visual field (which fall on the top parts of the retina)

A

– processed by medial LGN and visual cortex above the calcarine sulcus

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11
Q

describe the macula (colour, information of high acuity)

A

– processed by posterior LGN and
posterior 1/3 of visual cortex

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12
Q

describe the lateral geniculate body

A

-The lateral geniculate body is a small swelling beneath the posterior projection of the pulvinar of the thalamus
- Fibres of the optic tract terminate in the dorsal nucleus
-Receptive fields of LGN neurons: almost identical to the ganglion cells that feed them
-At the level of the lateral geniculate body the information from the two eye are kept separate

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13
Q

how many layers does the LGN have and describe the magnocellular LGN neurons, parvocellular LGN cells and nonM-nonp cells

A

-6 distinct layers
-Magnocellular LGN neurons: large centre-surround receptive fields with transient response –> layers 3-6 and these layers innervated by P-type retina cells
-Parvocellular LGN cells: small centre-surround receptive fields with sustained response –> layers 1, 2 and these layers innervated by M-type retina cells
-nonM-nonP retina cells project to K1-K6 (areas between layers) to the Koniocellular LGN layer

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14
Q

what layers for crossed and uncorssed fibres end in the LGN

A

-Crossed fibres end in layers 1, 4, &6
- Uncrossed fibres end in layers 2, 3, &5

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15
Q

what does the visual cortex (aka striate cortex) occupy?

A

-primary visual cortex occupies the upper and lower lips of the calcarine sulcus of the medial occipital lobe (area 17)

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16
Q

describe the geniculocalcarine tract

A

from the LGN to the V1 via this tract

17
Q

how many layers of the striate cortex

A

-6, I - VI
-IV –> broken up into IVA, IVB, IVC (alpha and beta)

18
Q

what is contained in layer IVC in V1?

A

spiny stellate cells (spine-covered dendrites)

19
Q

What layers are the pyramidal cells (spines and thick apical dendrites) contained in V1?

A

layers III, IVB, V, VI

20
Q

What layers are the inhibitory neurons (lack spines) in the V1?

A

all layers, form local connections

21
Q

Where do magnocellular LGN neurons project to in the V1?

A

layer IVC-alpha

22
Q

Where do parvocellular LGN neurons project to in the V1?

A

layer IVC-beta

23
Q

Where do Koniocellular LGN neurons project to in the V1?

A

-Koniocellular LGN axons make synapses primarily in layers I and III
-direct projections from koniocellular layers of LGN to blobs in layer II/III

24
Q

What are the patterns of intracortical connections in the V1

A

-Connections within the cortex are vertically organised

-preserves retinotopic mapping of layer IV through different cortical layers - hence cortical “columns”.
thought to be basis of information processing in cortex
- there are also lateral connections in layers III and V that may be involved in processing across the cortex e.g. for “perceptual binding

25
describe ocular dominance columns and cytochrome oxidase blobs
-ocular dominance columns in layer IV of primary visual cortex revealed by the radioactive amino acid tracer technique -Cytochrome oxidase: mitochondrial enzyme used for cell metabolism -Blobs: cytochrome oxidase-stained pillars in striate cortex -Each blob centered on an ocular dominance column in layer IV. -Receive koniocellular inputs from LGN -neurons in blob regions tend to have monocular, circular RFs with colour opponency
26
Describe the efferents of the striate cortex
-Layer II, III, and IVB cells project to other cortical areas. -Layer V cells project to the superior colliculus and pons. -Layer VI cells project back to the LGN
27
Describe the dorsal stream of visual information
–Analysis of visual motion and the visual control of action ("where") -V1, V2, V3, MT, MST, other dorsal areas -Area MT (temporal lobe): – Most cells are direction-selective, respond more to the motion of objects than their shape. -Beyond area MT—three roles proposed for cells in area MST (parietal lobe): –Navigation –Directing eye movements –Motion perception
28
Describe the ventral stream of visual information
–Perception of the visual world and the recognition of objects ("what") -V1, V2, V3, V4, IT, other ventral areas -Area V4—shape and colour perception – Achromatopsia: clinical syndrome caused by damage to area V4—partial or complete loss of colour vision -Area IT: – Major output of V4 – Receptive fields respond to a wide variety of colours and abstract shapes. – May be important for both visual perception and visual memory (such as faces)
29
What are the nonthalamic targets of the optic tract
-Participate in visual reflexes -Pretectal area: control size of the pupil, certain types of eye movement -Superior colliculus: orients the eyes in response to new stimuli—move fovea to objects of interest
30
Describe the role of pretectal area in vision
-Group of small nuclei rostral to the superior colliculus –Axons from the optic tract bypass the lateral geniculate body and enter the superior brachium -Innervates the olivary pretectal area –These neurons innervate the Edinger-Westphal nucleus of the occulomotor complex –These in turn innervate the ciliary ganglion which controls the sphincter pupillae muscle of the iris -Participates in the pupillary light reflex
31
describe the role of superior colliculus in vision
-Axons from the optic tract bypass the lateral geniculate body and enter the superior brachium -Collaborates with inputs from the parietal and occipital cortex, frontal eye field, pallidum, and spinal cord -Indicating the considerable integrative activity in the superior colliculus -Efferents innervate the oculomotor nuclei, pontine reticular formation, pretectal area, and spinal cord -Contributes to both voluntary and involuntary movement of the eyes and head required for fixation of gaze
32
describe the role of suprachiasmatic nucleus in vision
–Synchronises the intrinsic circadian rhythm in response to ambient illumination
33
What innervates the cerebellum with optics connections and what does this do?
-Accessory optic tract innervates the cerebellum via the tegmentum and inferior olivary nuclei –Coordination of movement of the eyes and head