Vitamin B Flashcards

1
Q

B-complex vitamins are ___________ soluble

A

Water soluble

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2
Q

Name of vitamin B1

A

Thiamin

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3
Q

Thiamin structure

A

Pyrimidine and Thiazole

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4
Q

What is the coenzyme form of Thiamin

A

TDP and TPP

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5
Q

Sources of Thiamin

A

Yeast
Pork
Legumes
Whole and enriched grains
Sunflower seeds

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6
Q

What are the 3 functions of Thiamin

A

Energy transformation
NADPH and Penrose
Nerve conduction

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7
Q

Energy transormation

A
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8
Q

NADPH and pentose

A
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9
Q

Nerve Conduction

A
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10
Q

Thiamin Deficiency

A

Beri Beri
Wear i KE-Korsakoff

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11
Q

Thiamin Toxicity

A

No UL
Large doses may help MSUD patients

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12
Q

Thiamin Assessment

A
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13
Q

What is the name of Vitamin B2

A

Riboflavin

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14
Q

What is the structure of VitB2/Riboflavin?

A

Flavin and ribitol

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15
Q

What are the 2 coenzyme forms of riboflavin/B2?

A

FMN and FAD

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16
Q

What are sources of Riboflavin/B2?

A

Milk
Dairy
Eggs
Meat
Legumes
Enriched grains

17
Q

Riboflavin/B2 is sensitive to ___________

A

UV Light

18
Q

What are the 6 function of Riboflavin/B2?

A
  1. Energy transformation
  2. Purine catabolism
  3. Vitamin B6 activation
  4. Folate activation
  5. Reduction of glutathione
  6. Niacin synthesis
19
Q

What are the 3 Riboflavin/B2 deficiency ?

A
  1. Cheilosis
  2. Angular stomatitis
  3. Glossitis
20
Q

Cheilosis

A
21
Q

Angular stomatitis

A
22
Q

Glositis

A
23
Q

Who is at risk for Riboflavin/B2 deficiency?

A
  1. Elderly
  2. Some cancers
  3. Alcoholism
  4. Elevated metabolism
24
Q

Does Riboflavin/B2 have a toxicity concern?

A

None reported
No UL

25
Q

How do to assess riboflavin/B2?

A

Red cell glutathione reductase bc FAD is important in reducing glutathione

26
Q

What is the name of Vitamin B3

A

Niacin

27
Q

Structure of niacin/B3

A

Nicotinic acid and nicotinamide

28
Q

What are the coenzyme forms of niacin B3?

A

NAD, NADH, NADP, NADPH

29
Q

sources

A

MFP, enriched grains legumes

30
Q

Synthesized from

A

Tryptophan

31
Q
A

60mg try - 1mg nicain

32
Q

Function

A
  1. Energy transformation
  2. HMP shunt
  3. Fatty acid synthesis
  4. Conversion of vitamin C, glutathione, folate to reduced states
  5. Lower cholesterol
33
Q

How does niacin lower cholesterol

A
34
Q

Niacin b3 deficiency

A

Pellagra
Dermatitis
Diarrhea
Dementia
Death

35
Q

niacin B3 deficiency at risk

A

Isoniazid users reduces niacin synthesis
Low intake (alcoholics)
Elevated metabolism
Low protein and low tryptophan diet (corn)