Vitamin C/Ascorbic Acid Flashcards Preview

Nutritional Biochem II > Vitamin C/Ascorbic Acid > Flashcards

Flashcards in Vitamin C/Ascorbic Acid Deck (21)
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1
Q

One hydrogen off of ascorbic acid is

A

ascorbate

2
Q

Two hydrogens off of ascorbic acid is

A

dehydroascorbate

3
Q

What are the transporters for Vit C

A

sodium dependent transporters 1 and 2 (SVCT1 and 2)

4
Q

what destroys ascorbic acid

A

heat, oxidation, alkaline solutions

5
Q

what are the functions of vitamin c

A

cofactor, antioxidant, hydroxilation, collagen synthesis, carnatine synthesis, tyrosine metabolism, neurotransmitter synthesis, proxidant, enhance immune function

6
Q

what is the common interaction we see with Vitamin C

A

Vit C increases absorption of nonheme iron

7
Q

In what way does Vitamin C influence Iron

A

Stabilizes from ferric (F3+) to Ferrous (F2+)

8
Q

What are some excellent sources of vitamin C

A

red peppers, oranges, orange juice, kiwi, broccoli, strawberries, brussels sprouts

9
Q

what are some good sources of vitamin c

A

spinach, green peas

10
Q

where is Vitamin C absorpbed

A

in the small intestine, usually the proximal jejunum

11
Q

what transporters are used to transport dehydroascorbic acid

A

GLUT 1 and 3

12
Q

what happens to excess vitamin C

A

excreted in urin within 6 hrs

13
Q

how to classify scurvy

A

total pool <300mg, plasma <0.2mg/dL

14
Q

what are the four Hs of scurvy s/s

A

hemorrhagic, hyperkeratosis, hypochondriasis (neurological), and hematologic abnormalities

15
Q

examples of deficiency s/s

A

fatigue, malaise, impaired wound healing, arthralgia,petechiae, corkscrew hair, swollen/bleeding gums

16
Q

toxicity s/s

A

osmotic diarrhea, ab pain

17
Q

what are some population based toxicity

A

renal dysfunction due to nephrolithiasis (kidney stones) and iron toxicity for individuals with disorders of iron metabolism

18
Q

what is the RDA for Vit C

A

90mg Men, 75 mg Women

19
Q

what are the recommendations for smokers

A

increase their vit C intake by 35 mg

20
Q

what are the recommendations for pregnant women

A

increase vit C intake by 100mg

21
Q

what is the TUL for vit C

A

2g both men and women