Vitamins - IN Flashcards

1. Make Money 2. No Vacations (43 cards)

1
Q

What are the Lipid Soluble Vitamins

A

ADEK

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2
Q

What are the Water Soluble Vitamins

A

B, C

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3
Q

In what ways can symptoms of deficiency arise

A

poor nutrition, increased demand, absorption problems, interactions with medications

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4
Q

what is DRI

A

dietary reference intakes, tables that give global view of requirements and toxic levels

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5
Q

What is RDA

A

recommended daily allowance, one component of DRI, defined as amount sufficient to meet the nutrient requirements of 97-98% of healthy individuals in a given group, varies by population

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6
Q

What are the functions of vitamin A

A

visual cycle (rhodopsin and cone opsins), synthesis of glycoproteins and mucopolysaccharides, retinoic acid, hormone actions, antioxidant

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7
Q

What are the symptoms of Vitamin A deficiency

A

Night blindness (early), xerophthalmia (advanced), follicular hyperkeratosis, anemia despite normal iron intake, poor growth in children, susceptibility to cancer and infections

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8
Q

What is follicular hyperkeratosis

A

looks like goosebumps but dont retract when rubbed

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9
Q

what groups are susceptible to Vitamin A deficiency

A

Poor, malnourished, premature babies

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10
Q

what are symptoms of vitamin A toxicity

A

Vit A accumulates in the liver, excess intake usually from enormous supplement doses, causes nausea, diarrhea, bone pain, scaly skin, orange tint to skin

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11
Q

What are the functions of Vitamin D

A

maintaining bone, calcium homeostasis, hormone actions

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12
Q

What are the symptoms of Vitamin D deficiency

A

rickets in children, osTIDomalacia in adults (bones not as dense but dont get pocketed bone loss a la osteoporosis), increased susceptibility to breast/other cancers, metabolic syndrome, diabeetus, infections

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13
Q

what populations are susceptible to vitamin D deficiency

A

poor, elderly, alcoholics

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14
Q

what are the functions of Vitamin E

A

antioxidant - scavenges free radicals and nerms them up, protects every membrane in every cell in the body from damage, prevents oxidation of LDL-C

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15
Q

what are symptoms of Vitamin E deficiency

A

cardiovascular disease, neurological symptoms

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16
Q

what populations are susceptible to Vitamin E deficiency

A

long term absorptive defect patients (celiacs), genetic defects - rare as fuck

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17
Q

what are the functions of vitamin K

A

localization of enzymes used for blood clotting, helps catalyze addition of g-carboxyglutamate to clotting enzymes

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18
Q

what are the symptoms of vitamin K deficiency

A

bruising, bleeding, hemorrhage

19
Q

what populations are susceptible to Vitamin K deficiency

A

anyone who doesnt absorb well - newborns, long term antibiotics patients, elderly, roux-en-y patients

20
Q

where is vitamin K found

A

Kale, Klebsiella

21
Q

What are the functions of vitamin C

A

whining at graduation, cofactor for oxidases in collagen formation, required for synthesis of steroids in stress response, iron absorption, antioxidant

22
Q

what are the symptoms of Vit C deficiency

A

mild - bruising, immunocompromise; severe - scurvy (decreased wound healing, osteoporosis, hemorrhage, anemia, fatigue), corkscrew hairs and pinpoint hemorrhages

23
Q

what populations are susceptible to vitamin C deficiency

A

poor diet, smokers, long term aspirin users, oral contraceptive users, corticosteroid patients

24
Q

what are the sub categories that make up B vitamins

A

energy releasing and hematopoietic

25
why is one sub category of B vitamins called hematopoietic
because deficiency leads to anemia
26
What is B1
Thiamine
27
What is the function of Vitamin B1
required cofactor for several enzymes in cellular energy metabolism - precursor of TPP
28
what are the symptoms of B1 deficiency
mild - GI, depression, fatigue moderate - Wernicke-Korsakoff severe - Beriberi
29
What is B2
riboflavin
30
what are functions of B2
precursor of FAD, FMN, key coenzymes for redox reactions in energy metabolism
31
what are symptoms of B2 deficiency
rare - ariboflavinosis - rash around nose, inflammation of mouth and tongue, burning and itchy eyes, light sensitivity
32
what is B3
Niacin
33
what is the function of B3
precursor of NAD, NADP, given to patients with hypercholesterolemia or hypertriglyceremia
34
what are symptoms of B3 deficiency
pellagra (4Ds) worsened by exposure to sun
35
who is susceptible to B3 deficiencies
people with corn or millet based diets
36
What is B5
pantothenic acid
37
what is B4?
TRICKED YA THERE IS NO B4
38
what are functions of B5
required for synthesis of CoA
39
what is B6
pyridoxine
40
what is the function of B6
precursor for pyridoxyl phosphate (PLP) an enzyme cofactor required for glycogen breakdown and GABA synthesis
41
what are the symptoms of B6 deficiency
more frequent than other Bs mild - irritability, nervousness, depression severe - peripheral neuropathy, convulsions, decreased glucose tolerance, hyperhomocysteinemia and anemia
42
what is B7
Biotin
43
What is B7's function?
coenzyme for several carboxylases