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Oral Pathology D2 > Vsiculo-Bollous > Flashcards

Vsiculo-Bollous Flashcards

(55 cards)

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1
Q

Definition of PATHOPHYSIOLOGY

A

the physiology of abnormal states; specifically : the functional changes that accompany a particular syndrome or disease

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2
Q

Definition of ETIOLOGY

plural etiologies

A

1: CAUSE, ORIGIN; specifically : the cause of a disease or abnormal condition
2: a branch of knowledge concerned with causes; specifically : a branch of medical science concerned with the causes and origins of diseases

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3
Q

Definition of PATHOGENESIS

A

the origination and development of a disease

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4
Q

1) Vesicle
2) Bulla
3) Erosion
4) Ulcer

A

1) Vesicle - fluid, <0.5
2) Bulla -fluid, >0.5
3) Erosion - no size, many colors
4) Ulcer -all layers of epi gone with microscopic death of cells

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5
Q

ramsay hunt syndrome

A

caused by herpetic zoster

*sever unilateral facial palsey

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6
Q

steroids indicated or not for zoster infections?

A

NOT indicated

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7
Q

Zoster vs Simplex

A

Zoster- unilateral, longer duration must treat acyclovir

Simplex- bilateral, shorter duration

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8
Q

hand-foot-mouth virus?

A

piconavirus, part of Coxsackie

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9
Q

Herpangina virus?

A

Coxsackie type A

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10
Q

Measels

A

Paramyxovirus
KOpliks spots
RubeOla
Warthin-Finkeldey giant cells (macrophages)

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11
Q

German Measels

A

Germans eat nutELLA (Rubella) while wearing TOGAS (virus) and kill (abort) babies
**NO Kopliks spots

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12
Q

MMP

sexes? appearance? histo?

A

women more
bright red patches, short lived, rare bullae
Nikolsky’s sign
epithelial clefting

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13
Q

pemphigus vs MMP you see what antibodies?

A

Pemphigus: IgG &C3

MMP: IgG, C3 AND IgA

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14
Q

Tzank cells

A

large glassy nucleus’s

Herpes, Varicella Zoster, PV

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15
Q

Warthin-Finkeldey giant cells

A

multinucleated giant cells in lymph tissue from measels (rubeola)

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16
Q

1) Pemphigus hyper?
2) pemphigoid?
3) TB
4) EM
5) drugs
6) angio edema
7) stomatitis Venenata

A

1) Pemphigus hyper? type 2
2) pemphigoid? type 2
3) TB type 4
4) EM type 2 or 3
5) drugs = IgE type 1
6) angio edema type 1
7) stomatitis Venenata type 3 or 1

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17
Q

1) pemphigus targets?
2) pemphegoid?
3) epidermolysis bullosa? herditary
4) MMP

A

1) desmoglein 3
2) BMZ and hemodesmosomes
3) collagen of anchoring fibrils
4) laminin 5 (epiligrin)

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18
Q

symblepharon

A

Scar at the canthus from MMP

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19
Q

entropion

A

inversion of the Eyelashes from MMP

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20
Q

trichiasis

A

Trauma to cornea from MMP

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21
Q

PV age? phenotypes? sexes? severe form?

A 
40-50 years
equal between sexes
HLA phenotypes
nikoskys sign
paraneoplastic pemphigus is sever form/malignant
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22
Q

nikolsky’s sign?

A

PV and MMP

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23
Q

BP (bullous pemphihoid)

related to? differs how?

Study These Flashcards
A

related to MMP

deffers bc detachment antigens are laminin, BP230and BP180
*old poeple 70-80, skin and oral

24
Q

EB (epidermolysis Bullosa)

forms? nails?

Study These Flashcards
A

aquired form and genetic (can only do direct if genetic)
dystophic nails
heals with scars

25
red mouth
``` PV EB erythema multiform steven johnsons EM ```
26
factitial
self induced traumatic ulcer
27
riga-fede disease
mechanical traumatic ulcer due to baby being born with teeth and biting
28
necrotizing sialometaplasia
ONLY in palate - death of salivary gland
29
syphillus caused by
treponema pallidum
30
primary, secondary and tertiary syphillus
primary- chancre secondary- condyloma latum, oral mucous pathces, maculopapular rash tertiary- gumma, mucosal atrophy, cardio and neuro
31
congenital syphillus
saddle nose saber shin hutchinson's triad (mulberry molars, scredriver incisors, 8th nearve deafness, keratitis)
32
fellatio? | seen in?
oral stimulation of a man's penis | *seen in gonorrhea caused by neisseria gonorrhoeae
33
Langhans giant cells seen in? describe disease
TB * tongue and palate non-healing ulces * central caseous necrosis
34
what has inuration?
TB cancer actinomycosis
35
Actinomycosis | discharge? bacteria? histo?
discharge sulfer granules gram + anaerobic basophilic core with eosinophilic periphery
36
histoplasmosis
deep fungal from bat and pigeon droppings
37
coccidioidomycosis
deep fungal from desert soil
38
blastomycosis
deep fungla from moist soil and mold
39
cryptococcosis
deep fungal from avian poop (Cry of the Bird)
40
minor aphthae vs major aphthae vs herpatiform
minor- 1-5 small, mobile, NO scar, symetric major- mobile, YES scar, assymetric, larger herpatiform- 10-100 small ulcers, anywhere, symetric
41
debacterol
chemical cautery used for aphthous ulcers
42
granulomas happen in?
chrons, TB, syphillis, histoplasmosis, all deep fungal
43
Behcet's syndrome?
more common in men brother to aphthous ulcers, more serious T-lymph infiltrate
44
EM (erythema multiforme) | minor vs major? lesions?
type 3 - minor- infections - major- drugs - bilateral recurrent bullseye lesions - short duration and acute - ANYWHERE but avoids gingiva
45
angioedema
IgE type 1 - heriditary= C1 esterase defeciency - induced= ACE inhibitor
46
stomatitis Venenata
direct contact with allergin
47
stevens johnson syndrome
mouth, eyes, skin, genitals | *sever form of EM
48
lichenoid drug reactions | Ex? Histo?
non-specific - liquifaction of basal cells - perivascular - scattered eosinophils Example is stomatitis venenata (direct contact and type 3)
49
wegener's granulomatosis | Classes? Characteristics?
- strawberry ginigvitus to attached gingiva * antineutrophil cytoplasmic antibodies and multinucleated giant cells - palatal perferation - 3 classes: classic (renal), limited (resp). superficial
50
candidal leukoplakia is premalignant why?
makes nitrosamines
51
TNM for tumor staging means?
``` T= tumor N= node M= metastasis ```
52
low vs high grade SCC
low= well defferenciated high= poor differenciation *worse*
53
SCC stage prognosis
``` 1/2 = 76% 3= 41% 4= 9% ```
54
3 parts to osteoradionecrosis? | *how to prevent?
1) hypoxia 2) hypovascular 3) hypocellar * prevent with hyperbaric oxygen (more common in MAndible)
55
Midline granuloma vs contact allergies
midline= Malignancy of t-lymphocytes Contact allergies= t-cell mediated immune response

Oral Pathology D2 (8 decks)

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