VTE Flashcards
(20 cards)
Why is VTE a significant concern in pregnancy?
It is a major cause of maternal morbidity and mortality due to physiological changes increasing thrombotic risk.
What are the three physiological changes in pregnancy that increase VTE risk?
Venous stasis, hypercoagulability, and endothelial injury.
Name a pre-existing condition that significantly increases VTE risk.
Previous venous thromboembolism (VTE).
What congenital thrombophilias increase the risk of VTE?
Antithrombin deficiency, protein C deficiency, protein S deficiency, and factor V Leiden.
Which acquired thrombophilia is linked to VTE in pregnancy?
Antiphospholipid syndrome, including lupus anticoagulant and anticardiolipin antibodies.
How does maternal age affect VTE risk?
Age over 35 years increases the risk.
What BMI level increases the risk of VTE in pregnancy?
BMI greater than 30 (obesity) increases risk.
Does a BMI less than 18 increase the risk of VTE?
No, it does not increase VTE risk.
What effect does high parity have on VTE risk?
Parity greater than 4 increases the risk.
Why is paraplegia a VTE risk factor?
Due to immobility and venous stasis.
How does sickle cell disease contribute to VTE?
It causes hypercoagulability and endothelial injury.
Name two inflammatory or chronic medical disorders that increase VTE risk.
Inflammatory bowel disease and nephrotic syndrome.
What myeloproliferative disorders are associated with VTE?
Essential thrombocythaemia and polycythaemia vera.
What is the risk of ovarian hyperstimulation syndrome regarding VTE?
It is a transient risk factor due to increased blood viscosity.
How does hyperemesis gravidarum lead to VTE?
Through dehydration and hemoconcentration.
Why is long travel a VTE risk?
Prolonged immobility during travel increases venous stasis.
How does severe infection, like pyelonephritis, contribute to VTE?
It causes systemic inflammation and endothelial damage.
Why is prolonged labour a VTE risk?
Due to increased immobility and endothelial injury.
What is the impact of excessive blood loss on VTE risk?
It may lead to increased clotting activity and immobility.
Why do postpartum surgical procedures increase VTE risk?
Due to endothelial injury, immobility, and activation of clotting pathways.
