W1L3 Psoriasis

Question 1

Papulosquamous diseases? (3)

Answer 1

1. Psoriasis
2. Lichen planus
3. DLE

Question 2

Def Psoriasis?

Answer 2

Genetically determined common skin dis w chronic relapsing & variable c/p

Question 3

Etiology Psoriasis? (8) SHIT ED MC

Answer 3

1. Trauma
2. Infection
3. Hormonal
4. Sun light
5. Metabolic
6. Climate
7. Emotional
8. Drugs

Question 4

Pathology Psoriasis? (4) DAHM

Answer 4

1. Hyperkeratosis , parakeratosis and acanthosis
2. Absent granular layer
3. Munro micro abscesses
4. Dermis:- dil . Tortuous cap . And cellular infiltrate

Question 5

Clinical types Psoariasis? (4) (VEPA)

Answer 5

1. Psoriasis vulgaris
2. Erythrodermic psoriasis
3. Pustular psoriasis
4. Arthropathic psoriasis

Question 6

C/P Psoriasis vulgaris plaque form? (7)

Answer 6

1. Papules & plaques
2. Salmon pink erythema
3. Silvery white scales
4. Auspitz sign + ve
5. Koebner phenomenon
6. Chronic , remission and relapse
7. Sites: elbows, knees and sacrum

Question 7

Psoriasis vulgaris other sites?

Answer 7

• Scalp: discrete plaques or P. amanticia
• Nails: pitting, subungual keratosis, yellow discolor & onycholysis
• Intertriginous ps: smooth, shiny red plaques & itching
• Psoriasis of palm & sole
• Mucosal psoriasis

Question 8

Guttate psoriasis?

Answer 8

• Children and young adults
• Follow strept . Infection
• Subsides in 6w or plaque ps

Question 9

Erythrodermic psoriasis?

Answer 9

Entire skin is red and scaly

Question 10

Pustular psoriasis?

Answer 10

• Localized to palms and soles
• Generalized

Question 11

Arthropathic psoriasis?

Answer 11

Ps and arthropathy

Question 12

Treatment of psoriasis?

Answer 12

A-Topical
- Steroid topical I.L inj
- Tar 2-5% Tar + UVB (Gokerman technique)
- Salicylic acid 3% - Calcipotriol

B-Phototherapy: UVB (broad/narrow band)

C-Systemic
- Methotrexate - PUVA
- Etretinate - Cyclosporin
- Biologic: TNF alpha blocker (Etanercept)

Question 13

Def Lichen Planus?

Answer 13

Chronic/acute dis. of skin & M.M w distinctive clinical & path. features

Question 14

Etiology Lichen Planus? (3) SIU

Answer 14

• Unknown
• Virus inf
• Stress is predisposing factor

Question 15

Pathology Lichen Planus? (5)

Answer 15

1. Hyperkeratosis
2. Hypergranulosis
3. Liquifactive deg . of B.C.L
4. Saw – toothed appearance of rete ridges
5. Band like infiltrate in the upper dermis

Question 16

C/P Lichen Planus?

Answer 16

• Papules, itchy, polygonal, violaceous, w wickham’s striae
• Koebner phen +ve
• Sites: bilat & sym flexors wrists, forearms, sides of neck, inner thighs, sacrum, oral M.M & genitals
• M.M: streaks & plaques , painful erosions
• Nails: long . Striations, discoloration, splitting & pterygium
• Palm & soles: firm yellowish papules

Question 17

Clinical varieties LP? (5) FBLAH

Answer 17

1. Actinic L.P
2. Hypertrophic L.P
3. Linear L.P
4. Follicular L.P
5. Bullous L.P

Question 18

Course LP?

Answer 18

A) Remission:
- Acute → few week
- Chronic → 9-18w

B) Healing :
- Hyperpigmentation
- Atrophy atrophic L.P or annular L.P

Question 19

Treatment of lichen planus?

Answer 19

A-Topical
- Steroids
- I.L steroids

B-Systemic :-
- Antihistamines
- Etritenate
- Steroids
- PUVA

Question 20

Def Pityriasis Rubra Pilaris?

Answer 20

Chronic skin dis of unknown Aet

Question 21

C/P PRP? (6)

Answer 21

1. Scaly scalp
2. P.P keratoderma
3. Follicular hyper keratosis
4. Psoriasiform patches
5. +ve/–ve Eczematous plaques
6. Nail dystrophy

Question 22

Course PRP?

Answer 22

Chronic with partial or complete remission

Question 23

DD PRP? (2)

Answer 23

1. Psoriasis
2. Seb dermatitis