W2L2 Eczema & AD Flashcards
(32 cards)
Def Eczema?
Severe inflammatory skin reaction induced by external &/ internal factors
Stages of Eczema? (3)
1) Acute eczema
- Strong irritant
2) Subacute eczema:
- Repeated Weak irritants
3) Chronic eczema
Char Acute Eczema? (4E)
- Erythema
- Edema
- Vesicles
- Exudation +- crust
Char Subacute Eczema? (3)
- Mild erythema
- Papules & some scaling
- Caused by Repeated Weak irritants
Char Chronic Eczema? (4) DSLF
- Dryness
- Scaling
- Fissuring
- Lichenification (inc thickness, pigmentation & skin markings)
Clinical examples of eczema?
- Contact dermatitis (Exogenous eczema):
• Irritant contact dermatitis
• Allergic contact dermatitis
• Infective eczymatoid dermatitis - Atopic dermatitis (Endogenous eczema):
• Others: Pompholix, stasis dermatitis.
Def Contact Dermatitis?
Inflammation of skin due exposure to external agent (chem/phy)
Clinical types CD?
1) Irritant contact dermatitis
•Phototoxic contact Dermatitis
2) Allergic contact dermatitis
•Photoallergic C.D
3) Infective eczymatoid dermatitis
Irritant Contact Dermatitis?
Irritant: agent causing dermatitis on first exposure (non immunologic process)
Strong irritant as acids & alkalie -> acute eczema.
Repeated Weak irritants as soap, detergents, organic solvents, plant & Animal products -> subacute or chronic eczema
Phototoxic CD?
• Occur after activation of irritant by UVR
• Localized to areas of exposure
Examples of Phototoxic agent:
• Tar & psoralen paint, plants (phytophotodermatitis)
• Occur after activation of irritant jelly fish secretion by UVR on coming out of water
Def Allergic Contact dermatitis?
Immunologic process due exposure to allergen/sensitizer
Allergic Contact dermatitis?
Sensitizer: agent coz dermatitis after latent period as (nickel, lead, chrome, cosmetics, Jewelry, perfumes, topical antibiotics, anesthetics)
Acute, sub acute or chronic eczema
Photoallergic CD?
Occur after activation sensitizer by UVR
Example Photoallergic agent: Perfumes, cosmotics, sunscreen
C/P Infectious Eczematoid (Infective) Dermatitis? COPE
- Erythema
- Pustules
- Oozing
- Crust & maybe dry & scaly
Sites Infectious Eczematoid (Infective) Dermatitis? (5)
- Around discharging ear
- Wound
- Ulcer
- Sinuses
- +- scalp in Pediculosis, trunk in scabies.
Ttt Infectious Eczematoid (Infective) Dermatitis? (5)
- Topical drying lotion
- KMnO4
- Saline
- Topical Abic-steroid combination
- Systemic Abic.
Diagnosis of CD? (3)
- Lesions localized to site of contact (SUSPECT)
- Improvement eruption on elimination causative agent (irritant/sensitizer)
- Patch test
Prevention CD? (3)
• Avoid contact
• Protect skin
• Check early signs dermatitis
Treatment CD? (5)
- Removal of the cause
- Use emolient creams Hypoallergenic, & fragrance free
- Use before & after work
- Ensure all parts of hands are covered - Topical CS
- Systemic AntiHistamine
- Systemic steroid (severe cases)
Def Atopic Dermatitis?
Chronic relapsing itchy inflammatory skin dis w diverge C/P & personal/fam history Atopy
Atopy: group of genetic immune mediated diseases as Bronchial asthma , hay fever, allergic rhinitis & Atopic Dermatitis
Etiology AD?
Genetic defect in fillagerin gene = Defective skin barrier
C/P Of Atopic Dermatitis?
• Pruritus (itching) lead to rash
• Dry scaly skin
• Crusted lesions on face, scalp, trunk & extremities + Lichenification (w chronic course)
• Causes of symptoms exacerbation:
- Emotional stress
- Low humidity & Cold weather
- Seasonal allergies, Flowers pollen
- Cigarette smoke
- Exposure to harsh detergents , soaps, Rough clothes,Synthetic fibers or wool
- Dust, Animal fur or sand
- Perfumes, Cosmetic products
Stages of Atopic Dermatitis?
• Clinically
• Infantile Atopic Dermatitis.
• Childhood Atopic Dermatitis.
•Adulthood Atopic Dermatitis
Infantile atopic dermatitis?
Age: 2m- 2y
C/P : Itchy Oedematous discrete & conflunet papules & vesicles,
w oozing & crust
Sites: Face, trunk & extremities
Course: 50% clear at the age 2y
