W2 Prostaglandins Flashcards

1
Q

Eicosanoids

A

Signaling molecules made by oxidation of fatty acids

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2
Q

Arachidonic Acid

A
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3
Q

COX-1

A

Always on, house-keeping gene always regulating cell metabolism

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4
Q

PGE2

A

EP3 , thermogenesis, ACh, rapid contraction(shivering)

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5
Q

Lipoxygenase

A

LTA4-> Chemotaxis
LTC4-> Glutathione

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6
Q

Leukotriene B4

A

Tissue injury, AA release, LTB4

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7
Q

Neutrophils, Leukotriene B4

A

make, attracted, and activated by LTB4,
1.release enzymes
2.Phagocytosis
3.NETosis

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8
Q

Eosinophils, Leukotriene B4

A

make, attracted and activated by LTB4,
1.Dock on Parasites
2.release chemiclas
3.alergic reaction

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9
Q

Monocyte, Leukotriene B4

A

Circulated in blod, attracted by LTBB4
1.Phagocytoses
2.Proliferate

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