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Adv Physiology > W10 Lactation > Flashcards

W10 Lactation Flashcards

1
Q

Mammary Crest

A

White lines visible in embryo in 4 weeks,
Thick ectoderm

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2
Q

Primary Mammary bud

A

in Week 6 each a mammary crest turns into 1 bud (total 2 ) in human

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3
Q

Secondary Mammary bud

A

in Week 12, the structure is more complicated

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4
Q

Lactiferous ducts and Mammarry pit and Mammary gland

A

All form From 6 months to birth. No more growth and differentiation of XX and XY for first 2 years

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5
Q

Atrophic ducts -> ductal grown

A

Estrogen during puberty (8-13) years XX

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6
Q

Alveolar Growth
(singular Alveoli)
a group of Alveoli is called Lobule

A

Progesterone during pregnancy

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7
Q

Testosterones on mammogenesis

A

Low T inhibits mammogenesis

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8
Q

Adipose tissue

A

determines size of breast(everyone has)

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9
Q

Lactiferous ducts

A

tip of nipple duct (everyone has)

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10
Q

Alveolar epithelium

A

non secretory,

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11
Q

Lactocytes

A

are Alveolar epithelium that is changed to
secretory cells by hormones

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12
Q

Dopamine AKA prolactin inhibiting hormone PIH

A

From hypothalamus to ant pit, no prolactin from ant pit, not lactating

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13
Q

Mechanoreceptors in nipple

A

send message to hypothalamus through spine, stops dopamine (we don’t know how)

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14
Q

Prolactin

A

is synthesized in ant pit by Lactrotrphs when no dopamine

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15
Q

Lactocytes are activated by

A

Prolactin

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16
Q

In Milk, these materials released into milk by prolactin

A

There are AAs (Casein)
and Triglyceride fatty acids

17
Q

Oxytocin

A

made in hypothalamus and moved to Post pit
Receptor on myoepithelial cells (smooth muscle)

18
Q

Oxytocin secrets when

A

Handling baby, eye contact, smell of baby, and intercourse

19
Q

Milk ejection is fragile meaning

A

sensitive to stress, anxiety, fatigue SO LESS OXY means you have milk but cant get out

20
Q

Oxytocin binds to receptor in surface

A
  1. voltage gated Ca channel opens -> contraction
  2. Ca release inside cell -> contraction
21
Q

If you mimic pregnancy you can Lactate, any gender

A

Progesterone
Estrogen
Both are in birth control pills

Adv Physiology (6 decks)

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