WBC

Question 1

Neutrophilia

Answer 1

○ Cause: infection, inflammation, tissue damage/infarction.
○ Pregnancy, after exercise, corticosteroid use
○ Toxic change- left shift- see band form (precursor- non segmented)
○ Toxic granulation- vacuoles forming
○ CML

Question 2

Eosinophili

Answer 2

○ Allergy or parasitic infection (like strongloidiasis)
○ Asthma, eczema, drugs
○ CML

Question 3

Basophilia

Answer 3

○ Uncommon
○ CML

Question 4

Monocytosis

Answer 4

○ Chronic infection/inflammation

Question 5

Lymphocytosis

Answer 5

○ Transient viral infection
○ CLL (persistent)
○ Whooping cough - children

Question 6

Neutrotenia

Answer 6

• Chemotherapy/radiotherapy
  - Autoimmune/drugs or bacteria/viral infection
  - Ethnic- African
  - Risk of serious infection- treat with IV antibiotic

Question 7

Lymphopenia cause

Answer 7

HIV infection
-Chemotherapy/radiotherapy
-corticosteroids

Question 8

Hypersegmentated neutrophils

Answer 8

normal= 3-5 lobes
-right shift
From lack of Vit B12/folic acid - megaloblastic anemia