WBC Variants Flashcards

1
Q

Toxic Granulation

A

Dark purple-blue granules in PMNs and Bands.

Often seen with toxic vacuoles, Dohle bodies and a shift to the left.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Toxic Granulation Cause

A

Stimulation of granulocytic cells results in fewer mitotic divisions. Prevents normal dilution of nonspecific granules.

Often seen with toxic granules, Dohle bodies and a shift to the left.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Toxic Vacuoles

A

Clear holes contained in the cytoplasm of phagocytic cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Toxic Vacuoles Cause

A

Severe bacterial infection or toxic states

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Identify

A

Toxic Vacuoles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Identify

A

Toxic Granules

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Hypersegmentation

A

Segmented neutrophils with six or more nuclear lobes

Cells often larger than normal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

hypersegmentation Cause

A

Congenital or Megaloblastic change

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Identify

A

Hypersegmentation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Pelger-Huet Anomaly

A

Benign congenital hyposegmentation of PMNs

No granulocytes with > 2 nuclear lobes
Pince-nez and Stodtmeister cells
Increased bands

Pseudo Pelger-Huet will have some normal PMNs present

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Identify

A

Pelger-Huet Anomaly

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Reactive Lymph

A

Activated T-Lymphocyte

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Identify

A

Reactive Lymph

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Identify

A

Pelger Huet Anomaly

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Identify

A

Plasma Cell and Reactive Lymph

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Barr Body

A

Represent an extra X-Chromosome unnecessary for normal nuclear function

Expressed as a miniature lobe or “drumstick” protruding from the nucleus of PMNs

Normal in females. In males that are XXY or XXXY

Not Reported

15
Q

Identify

A

Barr Body

16
Q

Plasmacytoid Lymph

A

Activate B-Lymph

Slightly larger with darker royal blue cytoplasm and heavily clumped chromatin

Lacks very eccentric nucleus and well developed golgi of plasma cell

17
Q

Identify

A

Plasmacytoid

18
Q

Pyknotic Degeneration(necrobiotic)

A

Cell undergoing Apaptosis or programed cell death.

One or more dense masses.

Not nrbcs!!

19
Q

Identify

A

Pyknotic Cell

20
Q

Identify

A

Pyknotic Cell

21
Q

Smudge Cells

A

Cells destroyed by making peripheral smear.

Associated with increased cell fragility.
Often seen in CLL and ALL

Can add albumin and remake slide to avoid creating this artifact.

22
Q

Identify

A

Smudge Cell

23
Q

Septicemia

A

Bacteria in Blood

Reported!!

24
Q

Identify

A

Septicemia

25
Q

Identify

A

Septicemia