WBC Variants Flashcards
Toxic Granulation
Dark purple-blue granules in PMNs and Bands.
Often seen with toxic vacuoles, Dohle bodies and a shift to the left.
Toxic Granulation Cause
Stimulation of granulocytic cells results in fewer mitotic divisions. Prevents normal dilution of nonspecific granules.
Often seen with toxic granules, Dohle bodies and a shift to the left.
Toxic Vacuoles
Clear holes contained in the cytoplasm of phagocytic cells
Toxic Vacuoles Cause
Severe bacterial infection or toxic states
Identify
Toxic Vacuoles
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Toxic Granules
Hypersegmentation
Segmented neutrophils with six or more nuclear lobes
Cells often larger than normal
hypersegmentation Cause
Congenital or Megaloblastic change
Identify
Hypersegmentation
Pelger-Huet Anomaly
Benign congenital hyposegmentation of PMNs
No granulocytes with > 2 nuclear lobes
Pince-nez and Stodtmeister cells
Increased bands
Pseudo Pelger-Huet will have some normal PMNs present
Identify
Pelger-Huet Anomaly
Reactive Lymph
Activated T-Lymphocyte
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Reactive Lymph
Identify
Pelger Huet Anomaly
Identify
Plasma Cell and Reactive Lymph