Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

Skin, Muscle, Bone > Week 1 > Flashcards

Week 1 Flashcards

(72 cards)

Start Studying
1
Q

MOA of acyclovir

A

inhibits DNA synth to halt viral reproduction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

MOA of valacyclovir

A

inhibits DNA synth to halt viral reproduction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

MOA of famciclovir

A

Pro-drug of penciclovir, inhibits HSV DNA polymerase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

MOA of docosanol

A

interferes w/ adoption of viral envelope into cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

indications for acyclovir

A

HSV, VZV, EBV, CMV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

indications for valavyvlovir

A

HSV, VZV, EBV, CMV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

indications for famciclovir

A

HSV, VZV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

indications for docosanol

A

topical for HSV on lips or face

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

contraindications for acyclovir

A

use w/ caution in immunocompromised patients

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

contraindications for valacyclovir

A

use w/ caution in immunocompromised patients

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

contraindications for famciclovir

A

none really

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

contraindications for docosanol

A

not really

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

AEs for acyclovir

A

local irritation, NVD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

AEs for valavyvlobir

A

local irritation, NVD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

AEs for famciclovir

A

HA, nausea (tablets contain lactose)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

AEs for docosanol

A

none

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

drug interactions for the topical and oral meds used to treat skin infections

A

none

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

what medications cover MSSA and strep

A

cephalexin, dicloxicillin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

what is the empiric coverage for CA MRSA in outpatients

A

clinda, TMP-SMX, DCN or MCN, linezolid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

what is the treatment for suspected CA MRSA and beta-hemolytic strep?

A

clinda, TMP-SMX, DCN or MCN, linezolid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

MOA of neomycin

A

inhibits bacterial protein synthesis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

MOA of bacitracin

A

inhibits bacterial cell wall synthesis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

MOA of mupirocin

A

inhibits bacterial protein synthesis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

MOA of clindamycin

A

inhibits protein synthesis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
MOA of TMP-SMX
inhibits folic acid syntehsis
26
MOA of cephalexin
inhibits cell wall synthesis
27
MOA of dicloxacillin
inhibits cell wall synthesis
28
indications for neomycin, bacitracin
topical infections (scrapes, burns etc)
29
contraindications for neomycin, bacitracin
hypersensitivity, mycobacterium of fungal infection
30
AEs of neomycin, bacitracin
redness, contact derm., itching, anaphylaxis (staph resistance occurs in 48 hours!)
31
indications for mupirocin
impetigo, secondary skin infections, elimination of MRSA from nose of carriers
32
contraindications for mupirocin
hypersensitivity, not to be used in pregnancy
33
AEs of mupirocin
HA, local burning, pruritis
34
drug interactions of mupirocin
antibiotics diminish the effect of vaccines
35
indications for clindamycin
purulent and non-purulent SSTI, bacterial vaginosis suppository
36
contraindications for clindamycin
hypersensitivity, previous C. diff
37
AEs of clindamycin
topical: xeroderma, burning, pruritus oral: N/V/D, jaundice, easy bruising
38
drug interactions of clindamycin
antibiotics diminish the effect of vaccines
39
indications for TMP-SMX
broad spectrum, UTI, AOM, traveler's diarrhea, bite wounds, SSTI
40
contraindications for TMP-SMX
allergy to sulfa
41
AEs of TMP-SMX
SJS, hemolytic anemia, N/V/D, kernicterus, kidney stones
42
drug interactions w/ TMP-SMX
increase INR, decrease metabolism of phenytoin, decreased metabolism of methotrexate
43
indications of cephalexin
PEcK, impetigo
44
contraindications of cephalexin
hypersensitivity, possible cross reactivity w/ PCN
45
AEs of cephalexin
HA, dizziness, rash, may elevate INR
46
drug interactions of cephalexin
decreases metabolism of metformin
47
indications for dicloxicillin
staph, osteomyelitis, animal bites, impetigo
48
contraindications of dicloxicillin
PCN hypersensitivity, do not use in kiddos
49
AEs of dicloxicillin
hypersensitivity, C. diff, hemolytic anemia, N/V/D
50
drug interactions of dicloxicilli
inducer leads to decreased hydrocodone? PCN causes increase in serum methotrexate
51
pt. education for dicloxicillin
can make birth control less effective
52
allyamines (drug names)
terbinafine, griseofulvin
53
MOA of terbinafine
inhibits ergosterol production, therefore inhibiting fungal cell wall synthesis?
54
MOA of griseofulvin
fungistatic that arrests cells in metaphase
55
indications for terbinafine
topical: all tineas oral: onychomycosis, tinea capitis
56
indications for griseofulvin
tineas, infections by microsporun, epidermophyton, trichophytan
57
contraindications for terbinafine
hypersensitivities
58
contraindications for griseofulvin
hypersensitivities, do not use if pregnant
59
AE of terbinafine
HA, fever, rash, diarrhea, nasopharyngitis, cough, rare; SJS, exacerbation of lupus
60
DI of terbinafine
CYP inhibitor
61
AE of griseofulvin
HA, rash, urticaria, rare: SJS, jaundice
62
DI of griseofulvin
hormonal BC is less absorbed
63
triazoles (drug names)
fluconazole, itraconazole
64
indications of fluconazole
candidia, cryptococcal meningitis
65
indications of itraconazole
fungal infections in immunocompromised and immunocompetent pts. including blasto and histo. aspergillosis in pts. w/ amph B intolerance. Onychomycosis
66
contraindications of fluconazole
hypersensitivities
67
contraindications of itraconazole
hypersensitivities, pts. w/ hx of heart failure or at risk of heart disease, do not use while breastfeeding or if pregnant or intending to become pregnant
68
AE of fluconazole
N/V/D, HA, rash, some reports of SJS
69
AE of itraconazole
BLACK BOX warning: serious CV side effects including tachycardia and cardiac arrest, N/V/D, HA, rash, abd. pain, edema, hypertension, rare: SJS
70
DI of fluconazole
coadministration of CYP substrates may lead to QT prolongation and other drug interactions
71
DI of itraconazole
lots, drug inhibits CYP
72
imidazoles (drug names)
clotrimazole, miconazole, ketoconazole

Skin, Muscle, Bone (2 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions