Week 10 Flashcards
(138 cards)
Some underlying principles or respiratroy diseases in children
Pediatric patients are at higher risk for respiratory disorders due to anatomical risk factors
Oxygen consumption in infants is double that in adults, giving rise to an increased RR
biphasic response in children
Biphasic response – periodic cycles of hyperventilation due to hypoxia, but this hyperventilation is not sustainable in infants due to respiratory fatigue (see below)
why are lungs immature in children
Lung capacities and flows continue to increase until late adolescence
Therefore, pediatric patients don’t have the full capabilities of a normal adult lung
3 ways FRC is actively maintained in infants
- Sustained inspiratory muscles throughout the respiratory cycle maintains FRC
- Narrowing of the glottis during expiration – traps air in lungs
- Inspiration starting in mid-expiration
Upper airway differences in children (4)
what are the consequnces of these differences
TELT
- Bigger (relative) base of Tongue – has the ability to block upper airway
- Displacing the tongue by placing towel under back opens up airway
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Epiglottis – larger and floppier
- Advantage: makes a better seal from the airway for sucking
- Disadvantage: increased risk for aspiration during increased RR
- Location of Larynx – located higher in the neck (at C2-C3) than in adults (C4-C5)
- Trachea – smaller and less rigid
Lower airway differences in children (2)
what is the consequences of this difference
- Lower airway – increased resistance from increased narrowing
- Narrowing due to underdeveloped bronchioles
- Reduced collateral connections between bronchioles in infants → reduced collateral ventilation of alveoli → increase in risk for atelectasis (collapsed lung)
Chest wall differences in childern
what are the consequences
- Chest wall compliance is 3x than the lung compliance
- In infants, the chest wall is made up of cartilage, not bone; therefore, it has less elastic force to expand chest wall – increased work of breathing
- Decreased elasticity results in decreased ability to change tidal volume
- To increase minute ventilation, infants must increase RR because they cannot increase tidal volume
- As we age, ossification of the sternum leads to chest wall compliance = lung compliance, decreasing the work needed for expiration
- In infants, the chest wall is made up of cartilage, not bone; therefore, it has less elastic force to expand chest wall – increased work of breathing
what are the consequences of rib structure differences in children
- Lack of angulation of ribs and square shape of thorax in infants → does not allow for ribs to help diaphragm in breathing process → paradoxical inward rib movement during inspiration → increased work to maintain this breathing motion
- This is fixed by adulthood
whats the difference in the diaghram of ped patients what does this result in
- Diaphragm differences
- Lack of type 1 muscle fibers – tires easily
Signs of respiratory fatigue in pediatrics pts
- Head bobbing
- Grunting – noise made at the end of inspiration to increase pressure and keep air in
- Tripod stance – bent over posture to recruit as many muscles to get as much air in as possible
- Nasal flaring
“Talk about children sleeping.”
- Infants sleep more and spend more time in REM
- REM decreases your ability to breathe
- Decrease in minute ventilation
- RR decreases
- FRC decreases because muscles relax and only muscle working is diaphragm
- Upper airway resistance doubles – the tongue relaxes
- REM decreases your ability to breathe
Congenital diaphragmatic hernia
descritpion, diagnosis, complications
- Description: abnormal development of pleuroparitoneal canal → herniation of bowels into thorax → decreased development of lung and pulmonary vasculature
- Major concern is lung hypoplasia
- Diagnosis: prenatally via US
- Complications: pulmonary HTN, respiratory distress, decreased breath sounds on affected side
Congenital cystic adenomatoid malformation (CCAM)
descritpion, diagnosis, complications
- Description: lesion caused by localized arrest in the development of fetal bronchial tree and limited to a single lobe
- Diagnosis: bowel-looking structures on CXR
- Complications: malignancy, pneumothorax, infection, hemoptysis, respiratory distress
que es esto

Congenital cystic adenomatoid malformation (CCAM)
Pulmonary Sequestration
description, complications
- Description: sequestered lung lobe that is not connected to airway or proper pulmonary vasculature
- Connected to the aorta (in similar fashion to renal arteries)
- Result from abnormal tracheobronchial bud
- Complications: mainly asymptomatic, but can cause respiratory distress or recurrent infections
types of pulmonary sequesteration
Intralobar – lower lobes
Extralobar – posteromedial left lower chest
Bronchogenic Cyst
Description – cystic structure near tracheal bifurcation
ఇది ఏమిటి

Pulmonary Sequestration
zer da hau

Bronchogenic Cyst
Croup
description, diagnosis, complication, treatment
- Description: edema of subglottic tissues due to a viral infection (typically parainfluenza virus types I or II)
- Diagnosis: Most common cause of inspiratory stridor and barking seal-like cough
- Complications: “steeple” sign due to inflammation
- Treatment: humid and cool air
Epiglottitis
Description, diagnosis, etiology, treatment
- Description: airway obstruction with progressive edema of supraglottic structures
- Diagnosis: manifests with pain, fever, and stridor
- Etiology: bacterial (H. influenza)
- Treatment: abx
Bronchiolitis
description, natural history, diagnosis, treatment
- Description: acute inflammatory response in airways dominated by netrophilia
- Etiology: RSV
- Natural history: Initial upper respiratory symptoms with coryza, fever and cough, which precede abrupt lower respiratory symptoms (dyspnea and tachypnea)
- Diagnosis: widespread bilateral crackles; CXR shows overinflation and regional atelectasis
- Complications: otitis media, apneas, asthma
Obstructive sleep apnea (OSA)
descrpition, patho, symptoms
- Description: disturbed sleep due to abnormal breathing
- Pathophysiology: anatomic structures in the upper respiratory tract including the tonsils block airflow during sleep
- Signs/symptoms: snoring, paradoxical inward rib cage motion during sleep, apnea, night sweats
Obstructive sleep apnea (OSA)
complication, diagnosis, risk factors
- Complications: failure to thrive and other systemic organ-based problems (i.e. neuro, cardio, etc.)
- Diagnosis: nocturnal polysomnography (measures brain activity in conjunction with airflow)
- Risk Factors: certain congenital syndromes (down syndrome), sickle cell disease, obesity






























