week 12 alterations in cardiac function Flashcards
atherosclerosis
the abnormal accumulation of lipids and fibrous tissue in vessels
coronary atherosclerosis
blockages and narrowing of coronary vessels reduce blood flow to the myocardium
CAD is caused by myocardial ischemia
leading cause of death in US
heart disease
most prevalent cardiovascular disease
CAD
CAD s/s
angina pectoris
epigastric distress
radiating pain to jaw or left arm
CAD risk factors
DM peripheral arterial disease HTN smoking elevated LDL AAA
CAD prevention
diet to control cholesterol, fat exercise smoking cessation medication disease mgmt (DM, HTN)
cholesterol med groups
-statins fibrates resins (chole or cole) absorption inhibitors (Zetia) omega 3 (fish oil caps)
angina pectoris
syndrome characterized by episodes of intense pain or pressure in anterior chest
caused by insufficient coronary blood flow
worsened by emotional stress or physical exertion
stable angina
predictable, consistent
occurs with exertion
relieved by rest, NTG
unstable angina
frequency and severity of sx increased
may not be relieved with rest, NTG
intractable/refractory angina
severe incapacitating pain
variant angina
pain at rest with reversible ST-segment elevation
caused by coronary artery vasospasm
silent ischemia
objective evidence of ischemia but patient reports no pain
angina assessment
tightness, choking, heavy sensation frequently retrosternal, may radiate to neck, jaw, shoulders, back, arms (usually left) anxiety accompanies pain other sx: dyspnea, dizziness, n/v subsides with rest, NTG
angina medication
nitrates (ntg) beta blockers (-olol) calcium channel blockers (norvasc, cardizem) antiplatelets: plavix anticoags
most common chronic disease among US adults
hypertension (HTN)
hypertension increases risk for
premature death, disability
MI, CHF
stroke
CKD
hypertension definition
systolic BP > 140
diastolic BP >90
based on 2+ accurate measurements taken 1-4 weeks apart
primary/essential HTN
95% of HTN pts
no identifiable cause
secondary HTN
5% of pts
associated with renal disease, sleep apnea, pregnancy
symptoms of HTN
often asymptomatic (“silent killer”)
retinal/eye changes renal damage MI cardiac hypertrophy stroke
HTN risk factors
smoking obesity, sedentary lifestyle DM age microalbuminuria or GFR < 60
HTN assessment
retinal exam
12 lead EKG
labs