Week 12 - Systematic Review Flashcards
which research design is a systematic review primarily?
primarily: exploratory/observational
also explanatory/experimental and less so descriptive/qualitative
done or acting according to a fixed plan or system: methodical
systematic
a critical appraisal of a book, play or other work
review
a document often written by a panel that provides a comprehensive review of all relevant studies on a particular clinical or health-related topic/question.
systematic review
when is the systematic review created?
after reviewing and combining all the info from both published and unpublished studies and then summarizing the findings
name 5 components that make a review “systematic.”
- based on a clearly formulated question
- identifies relevant studies
- appraises quality of studies
- summarizes evidence by use of explicit methodology
- comments based on evidence gathered
name 5 reasons why we need systematic reviews.
- minimize the impact of bias/errors
- can help to end confusion
- highlight where there is not sufficient evidence
- combining findings from different studies can highlight new findings
- can mitigate the need for further trials
name the 3 most common types of systematic reviews.
- intervention
- prognostic
- measurement
to assess the evidence about the effects of a healthcare intervention
intervention systematic review
to assess the evidence of models or predictors of patient outcomes
prognostic systematic review
to assess the properties of health-status instruments or tools
measurement systematic reviews
name the 3 main steps in process of creating a systematic review.
- planning the review
- conducting the review
- reporting and dissemination
- identification of the need for the review
- preparation of a proposal for a systematic review
- development of a review protocol
planning the review
- identification of the literature
- selection of studies
- appraise quality of papers
- abstracting data from papers
- analysis and interpretation of data
conducting the review
- the report and recommendations
- getting evidence into practice
reporting and dissemination
step 1: the best and most useful questions are ones that are… (what 4 things)
- specific, not too broad and not too narrow
- can be answered with evidence (rather than ask for a value judgment)
- are not questions where all stakeholders agree on what ought to be done
- concern areas of controversy, or issues where we plainly have no idea of what the best course of action is, but there might be literature that might help decide.
the best questions to guide a systematic review of the evidence and the development of guidelines are ones that have been developed following which format?
PICOT
what does PICOT stand for?
population intervention comparator outcome(s) time point
name the 4 steps of writing a systematic review.
- come up with a research question.
- identify relevant publications
- appraise quality of studies
- summarize evidence
your development plan for identifying literature should include which 4 components.
- criteria for the literature search - key words, databases, dates to include
- inclusion and exclusion criteria
- types of studies you want to include
- a timeline for your project
name the 3 ways classes of studies.
class I class II class III
prospective, randomized, controlled clinical trial with masked outcome assessment, in a representative population.
class I
name the 4 components of class I.
- primary outcome(s) is clearly defined.
- exclusion/inclusion criteria are clearly defined.
- adequate accounting for dropouts and crossovers with numbers sufficiently low to have minimal potential for bias.
- relevant baseline characteristics are presented and substantially equivalent among treatment groups or there is appropriate statistical adjustment for differences.
prospective matched group cohort study in a representative population with masked outcome assessment that meets a-d of class I OR a randomized, controlled clinical trial in a representative population that lacks one criterion a-d.
class II
