Week 13: Chapter 45 - Calcium Channel Blockers

Question 1

Briefly describe the calcium channel and the relationships between intracellular and extracellular calcium concentrations as they affect smooth and cardiac muscle contractile function.

Answer 1

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Question 2

Describe the functional linkage between beta-adrenergic receptors and calcium channels in the heart.

Answer 2

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Question 3

Compare and contrast the sites of action of nifedipine with those of diltiazem or verapamil. Also, explain how the differences between the dihydropyridines and verapamil or diltiazem affect their clinical use and name the most common side effects.

Answer 3

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Question 4

Identify other drugs, noted and described in the cardiovascular unit, which should not be administered with calcium channel blockers (CCBs) because of the risk of excessive depression of cardiac contractility, rate, and electrical activity. Also, specify whether these precautions apply to dihydropyridine-type CCBs, just to verapamil or diltiazem, or to all CCBs, and explain why.

Answer 4

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Question 5

Calcium Channel

Answer 5

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Question 6

Dihydropyridine

Answer 6

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Question 7

Verapamil

Answer 7

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Question 8

Nifedipine

Answer 8

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