Week 13 - Specialist Interventions Flashcards
(54 cards)
Interventions targeting the drug
- psychoeducation/drug information
- Withdrawal management
- Pharmocotherapy
- Drug Screening
Psychoeducation/drug information
Brief process of information provision focused on the communication of varied aspects of disease and treatment related information
Aim:
– To help understand their disorder,
– Understand the meaning of symptoms and what’s known about cause
– Harm minimisation / safety information
– Explore treatment options
– Early identify relapse risks
What is the important information that needs to be shared?
– Effects and side effects, dosage, methods, and potential harms
– Correct inaccurate or dangerous information
– Explore treatment options
why is it useful for the pre-contemplation stage
– Avoids confrontation and argument
– Raises awareness
what works about this method?
- Strong evidence base in clinical trials and community settings, particularly when delivered by clinicians
- involves assessing consumption as well
as substance-related behaviour, and providing normative feedback and information on the impact of use. - Educating individuals on the impact of hazardous alcohol use on both mental and physical health may facilitate motivation to change behaviour
Withdrawal Management
- the medical and psychological care of a person experiencing withdrawal symptoms as a result of ceasing or reducing substance use
- Common ‘entry point’ into AOD treatment. In/out patient
- Generally speaking, withdrawal feels like the opposite of the drug. For example when withdrawing from a depressant like alcohol a person may feel restless and agitated, or have
tremors
Symptoms during with withdrawal
can be mild or severe depending on:
* Duration of use
* Substance
* Age
* Physical health
* Psychological characteristics
* Method of withdrawal
Outcome of withdrawal management
- Withdrawal management can be a stand alone treatment – with limited effectiveness
- Treatment outcomes enhanced when people engage in further treatment such as counselling or rehabilitation services
Pharmocotherapy
- the use of prescribed medication to
assist in the treatment of addiction. - Replacing a prescribed drug to treat a drug of dependence is used when:
- to reduce the intensity of withdrawal symptoms,
- to manage cravings, and
- to reduce the likelihood of a lapse or relapse by blocking a drug or addictive behaviour’s effect
Aims of pharmocotherapy
- preventing physical withdrawal
- helps to stabilise the lives of people who are substance dependent
- to reduce the harms related to substance use.
Agnoists and Antagonists
agonists - drugs that occupy receptors and activate them
antagonists - drugs that occupy receptors but do not activate them Antagonists block receptor activation by agonists
Naltrexone Maintenance Treatment
- Naltrexone is a long-lasting opioid antagonist.
- Naltrexone reduces both the rewarding effects of opioids / alcohol and craving for it.
Outcomes of Naltrexone
– Safe treatment
– For alcohol, 54% completed the 12 weeks of the treatment study: 39% abstained; 86% were consuming less alcohol by final visit than at baseline
* Outcomes best if highly motivated, employed, with good social support, older and with prior treatment experience
* Risk of overdose – removes tolerance
Methadone Maintenance Treatment
- Full opiate agonist
- For those unable to cease opiate use/manage withdrawal
– Maintenance rather than abstinence
– Often preferred choice for high levels of opiate dependence
– Can be useful for chronic pain treatment
– Protective treatment for released prisoners with opiate use histories - Selected GP and Alcohol and Drug Services only
- High retention in treatment
– Not as intensive - Reduces/does not eliminate heroin use for all
- Reduces HIV risk behaviour, criminal behaviour, and risk of overdose
Buprenorphine
- Partial agonist & partial antagonist
- Maintenance treatment
- Can be a detoxification aid
– Detoxification and withdrawal from Buprenorphine better tolerated than from methadone or heroin
– Less severe symptoms - Higher doses improve retention in treatment and reduce heroin use
- Can be taken in one, two, or three day doses (Double/Triple dosing options); long acting injectables
- compared to methadone theres slightly less retention in treatment and reduces illicit drug use to an equivalent or greater extent
Interventions for alcohol
- Naltrexone
- Acamprosate
- Antabuse
Acamprosate (Campral)
– Decreases cravings for alcohol in people who have been dependent on alcohol and are trying to abstain.
– Agonist and antagonist
– Maintenance: Does not prevent withdrawal symptoms
– Acamprosate significantly reduced the risk of returning to any drinking by 86% and increased the cumulative duration of abstinence by 11%
Antabuse (Disulfiram)
- Maintenance Therapy - with abstinence as a goal
- Blocks enzyme that metablises alcohol - Reacts with alcohol to make client feel very ill
- Designed as a deterrent to drinking - Unpleasant side effects and sensitivity to alcohol
- Disulfiram is a safe and effective treatment. Produced an abstinence rate of more than 50%. Individuals who have taken Disulfiram for an average of 20
months have showed the highest rates of abstinence - More effective if used in conjunction with counselling and ongoing support
Interventions for nicotine
- Nicotine replacement therapy
- Varenicline (Champix)
Nicotine replacement therapy (NRT)
- partial agonist
- temporarily replaces nicotine from tobcco to reduce motivation to consume and withdrawal symptoms, eases transition from smoking to abstinence
- increases of successfully stopping by 50-70%
- supports the reduction of use by people not wanting to completely stop
- most effective with counselling
Varenicline (Champix)
- Antagonist and partial agonist. Stimulates dopamine receptors whilst blocking nicotine receptors.
– Reduces cravings
– Lowers effects - the most efficacious smoking cessation medicine at up to 12 months
- Best with counselling and support
- Not recommended for young people
- Can be used with NRT
interventions for Methamphetamines: Tina trial
- There are currently no approved medications for treating methamphetamine dependence.
- Australian trial on the use of Mirtazapine
– Two small trials conducted in the USA found mirtazapine reduced
methamphetamine use and reduced symptoms of depression in people who use methamphetamine
Intervention for Cannabis
There are currently no approved pharmacotherapies approved for
treatment of cannabis use disorders
– Some medications appeared to show promise for treating individual
aspects of CUD.
– Psychosocial interventions should remain the first line