Week 2 Flashcards

1
Q

Mechanisms of ocular trauma

A

Blunt trauma
Penetrating trauma
Burns (chemical / physical)

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2
Q

What can blunt trauma lead to

A

Blowout fractures
Subconjunctival haemorrhage
Globe rupture
Hyphaemia
Traumatic uveitis

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3
Q

What injury mechanism can cause blowout fracture

A

Direct blow to the central orbit by fist/ ball

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4
Q

What can happen as a result of blowout fracture

A

Herniation
Trapdoor fracture

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5
Q

Which structure is likely to herniate in a blowout fracture

A

Inferior rectus muscle
Orbital fat

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6
Q

Where does the herniates go into

A

Maxillary sinus

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7
Q

Inferior rectus muscle herniation can cause

A

Diplopia
when ask the patient to look up, one eye cannot move up

But when ask the patient to look down, both eyes can

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8
Q

What is subconjunctival haemorrhage

A

Rupture of blood vessels in conjunctiva, releasing the blood into the space between conjunctiva and sclera

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9
Q

Besides from trauma, what else can cause subconjunctival haemorrhage

A

Heavy coughing
Strenuous exercise
Straining when constipated

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10
Q

What is hyphaemia

A

Blood in anterior chamber

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11
Q

What is traumatic uveitis

A

Inflammation of iris due to eye trauma

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12
Q

What is the urea

A

Layer behind the conjunctiva and sclera, containing iris, choroid and ciliary body

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13
Q

Why are corneal abrasions very sore

A

Due to dense sensory innervation of the cornea

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14
Q

What can be used to check for corneal lacerations

A

Fluorescein stain drops

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15
Q

Management of corneal laceration

A

Remove the foreign body causing it
Ocular lubricants
Analgesia
chloramphenicol if risk of infection

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16
Q

What is myotonic dystrophy

A

Group of inherited conditions that show muscle weakness and myotonia

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17
Q

What is myotonia

A

inability to relax after muscle contraction

18
Q

types of myotonic dystrophy

A

Classic dystrophia myotonica 1 (DM1)
Type 2 myotonic dystophy (DM2)

19
Q

Which type of myotonic dystrophy is more common

A

Classic dystrophia myotonica 1 (DM1)

20
Q

Myotonic dystrophia most commonly present at

A

20 years old

21
Q

Cause of classic dystrophia myotonic 1

A

Mutation in DMPK gene

22
Q

Presentation of myotonic dystrophia

A

Frontal balding in males
Long and thin face
Bilateral ptosis
Cataracts
Slurred speech
Loose jaw (mournful facial expression)
Muscle wasting and weakness

23
Q

What causes slurred speech in myotonic dystrophia

A

Myotonic tongue and pharyngeal muscles

24
Q

What cataracts are seen in myotonic dystrophia

A

Stellate posterior cortical cataract
Polychromatic cataract (Christmas tree)

25
What physical test can be done to identify myotonic dystrophia
Shake the patient's hand - the patient will be unable to release their hand due to myotonia
26
What is neurofibromatosis type 1
Genetic condition that causes tumours along the nervous system
27
Cause of neurofibromatosis type 1
NF1 gene mutation
28
Presentation of neurofibromatosis type 1
>6 cafe au last spots that are >5mm (pre puberty) or >15mm (post puberty) Axillary or inguinal freckling >2 neurofibromas of any type on skin Optic glioma >2 Lisch nodules
29
What is optic glioma
slow-growing brain tumor that arises in or around the optic nerve
30
What are Lisch nodules
Iris hamartomas (benign) that are seen as brown patches on the iris
31
What can optic glioma result in
Afferent pupillary defect Globe proptosis (the tumour is pushing the eyeball out)
32
What is afferent pupillary defect
pupils respond differently to light stimuli
33
Which thyroid disease causes eye disease
Grave's - hyperthyroidism
34
How does thyroid eye disease occur
Autoimmune disease caused by the activation of orbital fibroblasts by autoantibodies directed against thyroid receptors
35
Presentation of thyroid eye disease
Proptosis (unilateral / bilateral) Lid retraction Red, watery eyes Optic neuropathy (as the swelling worsens and compresses the optic nerve)
36
How does proptosis occur in thyroid eye disease
The autoantibodies target the extra ocular muscles and orbital fat which causes swelling behind the eye hence pushes the eyeball out
37
What habit can worsen thyroid eye disease
Smoking
38
Complications of thyroid eye disease
Optic neuropathy Exposure keratopathy Double vision
39
What is exposure keratopathy
corneal damage and infection occurs as the patient is unable to close their eyes
40
What causes double vision in thyroid eye disease
Fibrosis of the extra-ocular muscles limiting the gaze in certain directions