Week 2 - Depression Flashcards
Depressive Disorders
All share symptoms of: Sadness, emptiness, irritability, somatic (body) concerns, and impairment of thinking
All impact a person’s ability to __________
All share symptoms of: Sadness, emptiness, irritability, somatic (body) concerns, and impairment of thinking
All impact a person’s ability to function
Depressive Disorders Classification
Major depressive disorder
Others>
Disruptive mood dysregulation disorder
Persistent depressive disorder (previously dysthymia)
Premenstrual dysphoric disorder
Substance/medication-induced depressive disorder
Depressive disorder due to another medical condition
Major depressive disorder
Others>
Disruptive mood dysregulation disorder
Persistent depressive disorder (previously dysthymia)
Premenstrual dysphoric disorder
Substance/medication-induced depressive disorder
Depressive disorder due to another medical condition
Disruptive Mood __________ Disorder
-Diagnosed in children ages 6 to 18
Symptoms
-Constant and severe irritability and anger
-Temper tantrums out of proportion to the situation at least 3 times per week
-Exhibits symptoms in at least two settings: home, school, and with peers
Management
-Symptomatic medications; CBT & parent training & facial expression recognition training
Dysregulation
Persistent Depressive Disorder
Formerly known as ________
Low-level depressive feelings through most of each day, for the majority of days
>At least ______ in adults
> At least 1 year in children and adolescents
Must have two or more of the following:
-Decreased appetite or overeating, insomnia or hypersomnia, low energy, poor self-esteem, difficulty thinking, and hopelessness
Persistent Depressive Disorder
Formerly known as dysthymia
Low-level depressive feelings through most of each day, for the majority of days
>At least 2 years in adults
> At least 1 year in children and adolescents
Must have two or more of the following:
-Decreased appetite or overeating, insomnia or hypersomnia, low energy, poor self-esteem, difficulty thinking, and hopelessness
Premenstrual Dysphoric Disorders
Symptom cluster in last week prior to onset of a ________; include
>Mood swings, irritability, depression, anxiety, feeling overwhelmed, and difficulty concentrating
Symptoms decrease significantly or disappear with the onset of __________
Symptom cluster in last week prior to onset of a woman’s period; include
>Mood swings, irritability, depression, anxiety, feeling overwhelmed, and difficulty concentrating
Symptoms decrease significantly or disappear with the onset of menstruation
Substance-induced depressive disorder
Person does not experience depressive symptoms in the absence of ______________________
drug or alcohol use or withdrawal
Depressive disorder associated with another medical condition
CVA, Parkinson’s Huntington’s, Alzheimer’s, TBI, Cushing’s disease, hypothyroidism, arthritis, back pain, metabolic conditions, HIV, diabetes, infection, cancer, and autoimmune problems
CVA, Parkinson’s Huntington’s, Alzheimer’s, TBI, Cushing’s disease, hypothyroidism, arthritis, back pain, metabolic conditions, HIV, diabetes, infection, cancer, and autoimmune problems
Major Depressive Disorder
____ (or more) of the following in 2-week period
Weight and appetite changes
Sleep disturbances
Fatigue
Worthlessness or guilt
Loss of ability to concentrate
Recurrent thoughts of death
Psychomotor agitation
PLUS—at least one symptom is also either
-Depressed mood or
-Loss of interest or pleasure (anhedonia)
Five (or more) of the following in 2-week period
Weight and appetite changes
Sleep disturbances
Fatigue
Worthlessness or guilt
Loss of ability to concentrate
Recurrent thoughts of death
Psychomotor agitation
PLUS—at least one symptom is also either
-Depressed mood or
-Loss of interest or pleasure (anhedonia)
Major Depressive Disorder (Cont.)
-Persistent for minimum ______ - ______
-Chronic: Lasting more than ___ years
-Recurrent episodes common
-Symptoms cause distress or impaired function
-Episode not attributed to physiological effects
-Absence of a manic or hypomanic episode
-Persistent for minimum 2 weeks to 6 months
-Chronic: Lasting more than 2 years
-Recurrent episodes common
-Symptoms cause distress or impaired function
-Episode not attributed to physiological effects
-Absence of a manic or hypomanic episode
Depression Epidemiology
Leading cause of __________ in the United States
>Children and adolescents
>Older adults
Comorbidity
>Combination of anxiety and depression is perhaps one of the most common
Leading cause of disability in the United States
>Children and adolescents
>Older adults
Comorbidity
>Combination of anxiety and depression is perhaps one of the most common
Jeff’s parents have described his lack of interest in things he used to enjoy, like games with his friends, and his classes, which he used to like. This may be best described by the term
Inappetance
Impetance
Indolence
Anhedonia
Anhedonia
Depression risk factors
Biological factors
>Genetic (first-degree family members)
>Biochemical
…>Stressful life events
-Hormonal
-Inflammatory
-Diathesis-stress model
>Interplay between genetic and biological
-Cognitive
Biological factors
>Genetic (first-degree family members)
>Biochemical
…>Stressful life events
-Hormonal
-Inflammatory
-Diathesis-stress model
>Interplay between genetic and biological
-Cognitive
More risk factors of depression
-________ gender
-Adverse childhood experiences
-Stressful life events
-Neuroticism
-Other disorders, such as substance use, anxiety, and personality disorders
-Chronic or disabling medical conditions
-Female gender
-Adverse childhood experiences
-Stressful life events
-Neuroticism
-Other disorders, such as substance use, anxiety, and personality disorders
-Chronic or disabling medical conditions
Depression - assessment
-Assessment of suicidality
-Self-assessment
-Behavior/Affect: Anergia
-Mood: Depressed mood and anhedonia
-Emotions: Anxiety; feelings of worthlessness, hopelessness, guilt, anger, helplessness
-Thoughts/Perceptions: delusions and/or hallucinations
-Comorbidity: chronic pain (sometimes)
-Assessment of suicidality
-Self-assessment
-Behavior/Affect: Anergia
-Mood: Depressed mood and anhedonia
-Emotions: Anxiety; feelings of worthlessness, hopelessness, guilt, anger, helplessness
-Thoughts/Perceptions: delusions and/or hallucinations
-Comorbidity: chronic pain (sometimes)
Depression - Self-Assessment
Patients with depression: Often reject the advice, encouragement, and understanding
A nurse’s best response:
-Recognize unrealistic expectations for yourself or the patient
-Identify feelings that originate with the patient
-Understand the roles biology and genetics play in major depressive disorder
Patients with depression: Often reject the advice, encouragement, and understanding
A nurse’s best response:
-Recognize unrealistic expectations for yourself or the patient
-Identify feelings that originate with the patient
-Understand the roles biology and genetics play in major depressive disorder
Which question would be a priority when assessing for symptoms of major depression?
“Tell me about any special powers you believe you have.”
“You look really sad. Have you ever thought of harming yourself?”
“Your family says you never stop. How much sleep do you get?”
Do you ever find that you don’t remember where you’ve been or what you’ve done?”
“You look really sad. Have you ever thought of harming yourself?”
Depression - Nursing diagnosis
-Risk for suicide—safety is always the highest priority
-Chronic low self-esteem
-Imbalanced nutrition
-Constipation
-Disturbed sleep pattern
-Ineffective coping
-Disabled family coping
-Risk for suicide—safety is always the highest priority
-Chronic low self-esteem
-Imbalanced nutrition
-Constipation
-Disturbed sleep pattern
-Ineffective coping
-Disabled family coping
Depression - Outcomes identification
Recovery model
>Focus on patient’s strengths
>Treatment goals mutually developed
>Based on patient’s personal needs and values
Recovery model
>Focus on patient’s strengths
>Treatment goals mutually developed
>Based on patient’s personal needs and values
Depression
Implementation (Cont)
-Counseling and communication
-Health teaching and health promotion
-Promotion of self-care activities
-Teamwork and safety
Evaluation
-Tailored to each patient’s unique presentation
-Basic self-care, thought processes, self-esteem, and social interactions
Implementation (Cont)
-Counseling and communication
-Health teaching and health promotion
-Promotion of self-care activities
-Teamwork and safety
Evaluation
-Tailored to each patient’s unique presentation
-Basic self-care, thought processes, self-esteem, and social interactions
Communication Techniques
-Use simple, concrete words
-Allow time for a response
-Listen for covert messages
-Ask about suicide plans
-Avoid platitudes
When a patient is silent:
-Avoid direct questions
-Make observations to reinforce reality
-Use simple, concrete words
-Allow time for a response
-Listen for covert messages
-Ask about suicide plans
-Avoid platitudes
When a patient is silent:
-Avoid direct questions
-Make observations to reinforce reality
Evaluation
-Tailored to each patient’s unique presentation
-Basic self-care, thought processes, self-esteem, and social interactions
-Tailored to each patient’s unique presentation
-Basic self-care, thought processes, self-esteem, and social interactions
Choosing an antidepressant
-Symptom profile of the patient
-Side-effect profile (e.g., sexual dysfunction, weight gain)
-Ease of administration
-History of past response
-Safety and medical considerations
-Symptom profile of the patient
-Side-effect profile (e.g., sexual dysfunction, weight gain)
-Ease of administration
-History of past response
-Safety and medical considerations
Antidepressants
Selective serotonin reuptake inhibitors (SSRIs)
> __________ therapy
>Rare risk of serotonin syndrome
Serotonin norepinephrine reuptake inhibitors (SNRIs)
>SSRIs may be tolerated better
Tricyclic antidepressants
>Anticholinergic adverse reactions
Monoamine oxidase inhibitors
>Effective for unconventional depression
Selective serotonin reuptake inhibitors (SSRIs)
>First-line therapy
>Rare risk of serotonin syndrome
Serotonin norepinephrine reuptake inhibitors (SNRIs)
>SSRIs may be tolerated better
Tricyclic antidepressants
>Anticholinergic adverse reactions
Monoamine oxidase inhibitors
>Effective for unconventional depression
Newer Antidepressants
-Serotonin antagonists and reuptake inhibitors (SARIs)
-Norepinephrine dopamine reuptake inhibitor (NDRI)
-Noradrenergic and specific serotonergic antidepressant (NaSSA)
Two Other New Drugs for MDD
>Esketamine: an N-methyl-D-aspartate (NMDA) receptor antagonist an N-methyl-D-aspartate (NMDA) receptor antagonist
>Brexanolone (Zulresso): first and only FDA-approved medication specifically for postpartum depression
-Serotonin antagonists and reuptake inhibitors (SARIs)
-Norepinephrine dopamine reuptake inhibitor (NDRI)
-Noradrenergic and specific serotonergic antidepressant (NaSSA)
Two Other New Drugs for MDD
>Esketamine: an N-methyl-D-aspartate (NMDA) receptor antagonist an N-methyl-D-aspartate (NMDA) receptor antagonist
>Brexanolone (Zulresso): first and only FDA-approved medication specifically for postpartum depression