Week 2 pt 2 Flashcards

(54 cards)

1
Q

There are 3 main types of urinary incontinence; what are they?

A

Urge, stress, overflow

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2
Q

List and explain the mnemonic for incontinence causes

A

DIAPPERS
Delirium is most common in inpt
Infection > Incontinence is not a common sequela of cystitis
Atrophy due to post-menopause can lead to incompetence of urethra
>Treated with topical estrogen
Pharm: diuretics, alpha-agonists, antispasmodic
Psych: either a child who has been abused OR, in an adult, psychomotor retardation and/or despair from severe depression
Excessive Output problem which isn’t compensated
Restricted movement = Can’t get to the bathroom
Stool impaction physically affects bladder filling or drainage

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3
Q

To treat transient urinary incontinence, what is the main thing you need to do?

A

get to the root of the problem

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4
Q

List 8 characteristics of urge incontinence

A

Compelling desire to void
Leak before going to bathroom
Occurs supine or upright
Associated with diet
More than 8 voids in 24-hour period
Urgency
Frequency
OAB wet and (OAB dry)

Note: you may have urge incontinence that is from a transient cause

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5
Q

Give the pathogenesis of urge incontinence

A

1) Detrusor overactivity; increased contraction of detrusor attempting to void the bladder
2) Idiopathic or Secondary to bladder stone/kidney stone or tumor
>Therefore, if onset is abrupt, consider further workup
>Nor should treatment be continued indefinitely without consideration of these insidious causes

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6
Q

What are the main Sx of urge incontinence?

A

1) Intense urge to void followed by leakage
2) Most common cause of incontinence in the geriatric pt (esp elderly women)
3) Happens day and night

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7
Q

How do you diagnose urge incontinence?

A

Clinical
Cystometry will show random contractions irrespective of bladder fullness

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8
Q

How do you Tx urge incontinence?

A

1) Kegel exercises: “Stop the flow”
2) Bladder training
-Scheduled voiding, based on shortest length of duration between
-Lengthened periods using relaxation
weight loss
-Dietary modification
-Constipation tx
-Smoking cessation

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9
Q

List some of the biggest offenders that worsen urge incontinence

A

1) Coffee (even if decaf)
2) Tea
3) Pop
4) Alcohol
5) Spicy foods
6) Tomato based products
7) Chocolate
8) Non-nutritive sweeteners

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10
Q

List the meds for urge incontinence (only need to know one)

A

*Oxytrol 1 patch 3.9 mg/day twice a week
*Oxybutynin 5 mg po q 8 hours
*Tolterodine 4 mg po daily
*Oxybutynin ER 10 mg po daily
Trospiuim 20 mg po bid
Gelnique 10% 1 pump to skin daily
Vesicare 5 or 10 mg po daily
Toviaz 4 or 8 mg po daily
*Myrbetriq 25 or 50 mg po daily

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11
Q

Describe the etiologies of stress incontinence

A

Urethral incompetence; intra-abdominal pressure exceeds urethral closing pressure:
1) Any age woman; most common type in women (young>old)
2) hx multiple vaginal births
3) Male with radical prostatectomy
4) Occurring during the daytime
5) Reg bladder contractions

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12
Q

What are the Sx of stress incontinence?

A

Instantaneous leak with stress maneuver, like laughing, sneezing/coughing, standing/exercise

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13
Q

How do you Dx stress incontinence?

A

Clinical:
-Stand with full bladder and relax perineum
-Cough
-Immediate expulsion of urine
Don’t actually make them do that ^

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14
Q

Describe overflow incontinence

A

1) “Water over the dam”; leaks and do not realize it
-Full bladder
2) Leaks with stressful situations
3) High urinary residual
4) Obstruction vs flaccid bladder causes

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15
Q

How do you Tx stress incontinence?

A

1) Can try pelvic floor exercises/kegels
2) Pessaries in female patient/w/ w/o cystocele
3) Lifestyle/dietary modification:
-Decrease caffeine, carbonated, alcoholic drinks; and overall fluid intake*
4) Surgery to repair cystocele
-Cyst urethropexy-bladder sling
-Urethral injections (bulking)

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16
Q

1) What causes overflow incontinence? Give 2 examples
2) Is it common?

A

1) Detrusor underactivity: Idiopathic vs. lower motor neuron problem
-Trauma, MS
2) Least common type

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17
Q

Overflow incontinence:
1) Main Sx?
2) How do you Dx?

A

1) Nocturnal leakage
2) Cystometry will show no contractions
-Increased post void residual (approx. > 450mL); never completely emptying
-What is normal?

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18
Q

Overflow incontinence:
What are the 2 main treatments? Describe each

A

1) Cholinergic Agonist: Bethanechol*
-Stimulates parasympathetic nervous system
-This increases bladder muscle tone, causing contractions to initiate urination
2) Augmented voiding
-Suprapubic pressure, double voiding
-Catheter

  • = also used for retention
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19
Q

Urethral obstruction→ incontinence
1) What are some etiologies?
2) How do you Dx?

A

1) Prostate enlargement: BPH, Cancer
-Urethral stricture, bladder neck contracture
2) Clinical vs imaging
-Imaging for physical obstruction: cystourethroscope, retrograde urethrogram, voiding cystourethrogram, US

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20
Q

Urethral obstruction→ incontinence:
What are the Sx?

A

1) Dribbling incontinence post void
2) Hesitancy
3) Decreased force of stream
4) Straining
5) Overflow incontinence

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21
Q

Urethral obstruction→ incontinence:
What are the main treatments? (based on the 3 main causes)

A

1) BPH: Alpha antagonists
2) CA: Surgery, radiation
3) Physical obstruction: surgery, catheter

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22
Q

Functional Incontinence: What causes this?

A

Physical or mental impairment:
1. Totally oblivious to incontinence
2. Physical limitations getting to bathroom
3. Just do not want to make the effort

-cannot recognize the need to go
-cannot locate toilet
-cannot access toilet

23
Q

Nephrolithiasis/urolithiasis: What is the etiology? Explain

A

1) Calcium oxalate 85% of the time
2) Can also be calcium phosphate, struvite, uric acid, cystine
3) Inadequate hydration
4) Genetics? Potentially with common Ca2+ stones, but certainly with cystine

24
Q

Nephrolithiasis/urolithiasis:
Who is it more commonly found in?

A

1) Obesity, HTN, DM, carotid calcification, CVD, gastric bypass, gout, Crohn’s (don’t memorize)
2) There is a geographic component
Hot climates and high altitude
More often in summer months

25
Nephrolithiasis/urolithiasis: What are the Sx/ pt presentation?
1) Flank pain 2) Colicky (as ureter peristalses against stone) 3) Radiates anteriorly or to the groin 4) Pt moving a lot due to level of discomfort (worst at UV junction) 5) B/c they reoccur, they may tell you they have a h/o kidney stones and that their pain is comparable with past stones
26
Nephrolithiasis/urolithiasis: How do you Dx?
1) CT abdomen/pelvis without 2) Blood on UA is common but lack is by no means a rule out -You should also be checking for SUPERIMPOSED INFECTION
27
Nephrolithiasis/urolithiasis is a risk factor for what?
bladder CA
28
Describe Tx/management in ER for Nephrolithiasis/urolithiasis
Treat pain IVF Order UA & CT abd/pelvis without Catch the stone-strainer
29
Nephrolithiasis/urolithiasis: When might they pass? What can you do for these pts?
If under 5mm, they will often pass -Alpha 1 blocker -Tamsulosin sometimes -Pain control -P.O. fluids / Strain all urine -Watch for signs of infection -Follow with urology
30
Nephrolithiasis/urolithiasis tx: What medications work? Why?
Alpha-adrenergic receptor blockers: (like Tamsulosin) 1) Alpha 1A –adrenoreceptors are responsible for smooth muscle tone in the prostate and bladder neck 2) Alpha-adrenergic receptor blockers antagonize/blocks the receptors -Thus, loosening the tone -Thus, increasing urine flow
31
What kidney stone (Nephrolithiasis/urolithiasis) Tx is debated?
Some providers don’t feel Tamsulosin is efficacious, but almost everyone expects you to give it to your kidney stone pt female pts too
32
What should you do for pts with Nephrolithiasis/urolithiasis >5mm?
1) Urology consult 2) Consider admit if pain not controlled 3) They may place stent; they may use SWL (shock wave lithotripsy
33
What should you tell Nephrolithiasis/urolithiasis pts after Tx?
DRINK MORE WATER Change diet (possibly)
34
Describe further workup for Nephrolithiasis/urolithiasis
1) Analyze the stone 2) Labs -Chemistry >24-hour urine (optional in first stone, needed after that) >Volume, creatinine, pH, calcium, uric acid, oxalate, phosphate, sodium, citrate
35
Cystitis: Path?
Bacterial infection  E. coli #1 Females more often than men due to anatomy Cystitis in a male, therefore, should prompt further workup
36
Cystitis: Sx?
Dysuria which is “burning” in character Suprapubic pain Increased urgency, frequency May see change in smell or color (malodorous or darkening)
37
How do you Dx Cystitis (3 elements to this)
1) Urinalysis with culture: Culture is important because in ~ 2 days you will confirm sensitivity to your antibiotic choice 2) UA: Leukocyte esterase (not always nitrites) Pyridium confounds nitrite positive result (false +) Epithelial cells show you that the sample is contaminated and unreliable +/- hematuria 3) CT can show bladder wall thickening, but you should not order a CT to diagnosis this
38
What are the first line treatments for Cystitis? What do you need to worry abt with each?
1) Nitrofurantoin 100 BID x 5 days Watch out Creatinine Clearance less than 30-Beers criteria 2) Bactrim 160/800 BID x 3 days Caution renal dz 3) Fosfomycin 3g po +pyridium for pain, max 2d No contact lenses
39
What are the 2 second line Txs for cystitis? What is important abt these?
Ciprofloxacin BLACK BOX WARNING Levofloxacin BLACK BOX WARNING
40
What should you think of with male patient w cystitis?
Stone, obstruction, prostatitis, indwelling foley (high risk in either gender) Often this will be treated as complicated UTI
41
Complicated UTI Treated first with what? (x1)
1) Ceftriaxone 1g IV/IM +/- 2) Fluoroquinolones IV or po -Complicated UTI (inpt) will get broad > targeted coverage
42
What are some other considerations regarding cystitis?
1) Chemo SE 2) Bladder cancer: What is a major risk factor? 3) Voiding disfunction 4) Geriatric sx vary and are not textbook *no tx for asymptomatic bacteriuria except in pregnant pts, procedures with bleeding, and a few others
43
How can you prevent cystitis?
1) Drink more water 2) Completely void bladder 3) Urinate post coitally (females) 4) Estrogen cream (in atrophic vaginitis with more than 3 UTI/year)
44
When do you do medical ppx for cystitis?
Done for recurrent UTI (more than 3 UTIs/year) -After ruling out stones, reflux, fistula -After weighing the risk of prolonged abx -Then 6-12 months of abx >*unless a child-workup for reflux (lecture #1)
45
Interstitial Cystitis (IC): What is the etiology?
Etiology unknown; now considered a chronic pain syndrome Theories: allergy, autoimmune Dramatic exaggeration of normal sensations Pain occurs with filling of the bladder
46
Interstitial Cystitis (IC): What is the pt presentation? Who is it more common in?
1) Urgency, frequency, and pain Relief with voiding 2) 40+ female
47
Interstitial Cystitis (IC): How is it diagnosed?
1) Diagnosis of exclusion 2) UA normal 3) Cystoscopy ruling out: -Cancer, eosinophilic cystitis, tuberculous cystitis -Hx negative for cyclophosphamide exposure -Hx negative for radiation -Urethral diverticulum negative on exam -i.e. No compressible lump that expels purulent material from meatus -CA ruled out on bx
48
Interstitial Cystitis (IC): What are some treatments?
1) Nothing 2) Sometimes self-limiting-change diet and add exercise 3) Sometimes the hydrodistension accompanied as a part of cystoscopy helps 4) *Amitriptyline is first line 5) Pyridium 6) *Intravesicular: DMSO: 50cc wkly x 6-8wks; retained in bladder 10-20minutes Q tx very painful, garlic breath 1-2d; 50% response rate 7) BCG-phased out 8) Botulinum toxin A 9) Lidocaine 10) Allergy meds
49
Interstitial Cystitis (IC): What is the first line Tx? What is another option?
Amitriptyline; DMSO
50
Pyelonephritis: 1) Etiology? 2) Sxs?
1) Gram negative 2) Cystitis + fever and flank pain (CVA ttp)
51
Pyelonephritis: How is it diagnosed?
1) UA likely to demonstrate infection 2) UA may show WBC CASTS-renal origin 3) Also obtain urine culture 4) (Also obtain blood culture) CBC = elevated WBC with left shift 5) CMP
52
Pyelonephritis: What are some DDxs?
Appy, cholecystitis, pancreatitis, diverticulitis, lower lobe PNA, epididymitis, prostatitis, PID
53
Pyelonephritis: What are some complications?
Sepsis +/- shock Abscess formation (more likely in DM pts) Scarring
54
Pyelonephritis: How long can fever last? What do you do if it doesn't go away?
1) Fever can last 72 hours after starting tx 2) If present after 2 days (not downtrending), pt needs imaging 3) After fever is gone for 24 hours, can transition to oral medication