WEEK 2 QUIZ Flashcards
(10 cards)
Pharmacokinetics includes which of the following components?
a. Complications of drug therapy
b. Influence of drugs on metabolic processes
c. Mechanism of drugs on receptors
d. Influence of drugs on genes
e. Drug biotransformation in the organism
e. Drug biotransformation in the organism
Pharmacokinetics in the elderly is associated with:
a. decreased blood flow and increased cardiac output
b. increased first-pass metabolism in the liver
c. increased blood flow and decreased cardiac output
d. decreased glomerular filtration rate
d. decreased glomerular filtration rate
Plasma concentration of a medication:
a. will generally reach its peak more quickly after oral administration than after intravenous administration.
b. depends on dose and dose interval.
c. reached the same peak independently of how it is administered.
d. depends on genetics, age and gender.
b. depends on dose and dose interval.
Plasma protein bound medications:
a. are pharmacologically inactive
b. can freely diffuse to sites of action
c. are irreversibly bound to albumin
d. tend to have short half-lives
e. can readily cross the blood-brain barrier
a. are pharmacologically inactive
The development of tolerance describes a situation where:
a. a patient experiences withdrawal symptom if the medication is not given at regular intervals
b. the dose of a medication must be increased to maintain a given effect
c. the patient is unable to tolerate a normal dose of the medication
d. a response of unusually large magnitude is produced by a normal dose of a medication
e. an unusual type of response is produced by a medication
b. the dose of a medication must be increased to maintain a given effect
The half-life of a medication:
a. is the time taken for the plasma medication concentration to fall by one-half.
b. which is strongly protein-bound is likely to be shorter than that of a medication which is unbound.
c. is the time from administration until its maximal effect is reduced by half.
d. is the time from administration until half the dose has been excreted.
e. is half the time from administration until there is no medication left in the body
a. is the time taken for the plasma medication concentration to fall by one-half.
The therapeutic range of a medication:
a. is sometimes higher than the toxic range of medications.
b. overlaps the toxic range when higher doses are used than when lower doses are used.
c. is the number of different preparations of the medication found in the pharmacy.
d. is the range of plasma levels within which the medication is active but not toxic.
d. is the range of plasma levels within which the medication is active but not toxic.
What does the term “bioavailability” mean?
a. Amount of a substance in urine relative to the initial doze
b. Permeability through the brain-blood barrier
c. Fraction of the drug reaching the systemic circulation
d. The number of milligrams in the drug
e. Plasma protein binding degree of substance
c. Fraction of the drug reaching the systemic circulation
The signs and symptoms of an allergic reaction to penicillin include:
a. diarrhoea, glossitis, bradycardia
b. wheezing, pruritus, urticaria
c. headache, muscle pain, constipation
d. fever, joint pain, hypertension
b. wheezing, pruritus, urticaria
Which of the following aspects is NOT required in a prescription for a Schedule 4 medication?
a. The frequency of administration
b. Time of administration
c. The prescriber’s signature
d. Mechanism of action
e. The administration route.
d. Mechanism of action
