week 3 Flashcards

1
Q

acute bronchitis

A

viral pneumonia, copd pic
wheeze fever
crp normal
comsrbative mangement
if crp high - doxy
coryzal symps

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2
Q

ards

A

pao2<300, bilateral opacities, acute pnset
non cardio PO
prone psoitoning, A toE
ABG - refractory to oxygen
pul cap pressure <18mmhg

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3
Q

hydrocephalus

A

sah and meningitis
medical can be furosemide

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4
Q

motor neurone

A

ALS = mixed
PLS = UMN, Betz
PBP = both, absent jaw jerk, flaccid fasciculation of tongue, Donald duck speech
Pseudobulbar: UMN, increased jaw ja=erk, hot potato
PMA = LMN
riluzole -prolong 3 monthd
percutaneous gastrostomy tube
NIV
vit D if bed boung
eye spared, autonomic fx spared

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5
Q

myasthenia gravis

A

criss: lithium, BB - need for NIV, FVC low
diplopia. ptosis
hypernasal speech
plasmapharesis + IVIG in crisis
SCLC, brrast, ovarian cancer = Lambert
pyridostigmine

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6
Q

hypogonadism

A

eunucoid
chemo radio dmaage to gonads
menopause symps
buccal, oral, IM
gynaecomastia, erectile dsfucntion
DEXA
polycythaemia due to testosterone
haemochromatosis
pelvic imaging - amenorrhoea - structural defects

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6
Q

carcinoid

A

appendix, small inetstine
5-HIAA
right sided murmurs, bronchospasm,, wheeze, pulm stenosis
octreotide

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7
Q

prolactinoma

A

cabergoline/ bromocriptine
hypothyroid
amenorrhoea (secondary)
men1

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8
Q

thyroditis

A

riedel’s: woody painless, psc assoc
rapid thryoid enlargement: dyspnoea, dysphagia

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9
Q

nephrotic

A

Membranous nephropathy = SLE, hep B
Focal segmental glomerulosclerosis = HIV
4-6 weeks steroids
biopsy if haematuria, steroid unrepsonsive
3.5g/24 hours protein
anti PL2R = membranous glomerulonephritis

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10
Q

hydrocoele

A

straining, raising arms, coughing
tetsicular tumour
patent processus vainalis
torsion, tumour, epididymo orchitis
USS

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11
Q

fibroadenoma

A

> 3cm = surgical excision

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12
Q

aterial and venous

A

venous oozes and bleeds
sloping shallow
atrophie blanche

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13
Q

bppv

A

brandt daroff exercises
if no improvement by 4 weeks - follow
admit if unable to keep down fluids
saccade

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14
Q

viral labyrinthtisi

A

horizontal nystagmus towards unaffected side
prochlorperazine/ antihistamines

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15
Q

scleirtis

A

RA, SLE, sarcoid, granulomatosis w polyangitis
red eye, painful
same day assessment
NSAIDs
episcleritis, blanching vessels, not painful

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16
Q

reactive arthritis

A

sterile pyuria
circinate balanitis
NSAIDs may need PO steroids
dysentery

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17
Q

alcoholic hepatitis

A

Maddrey’s discriminant function to determine if need steroids for severe
3 months abstinence and best mx and sutiable candidate –> liver transplant

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18
Q

AI hepatitis

A

type 1: ANA, ASMA
type 2: ALKM
cushingoig features
steroids then axatjioprine (LFT and FBC)
6-12 monthly USS and AFP
liver biopsy
hypergammaglobulinaemia

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19
Q

diverticular disease

A

colovesical fistula -faecaluria, pneumaturia, brown urine
IV fluids, abx .etc. in itis
hartmann’s if peritonitis
brown coloured urine
CT
barium and colonoscpy can be done but perf in acute

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20
Q

aspergillus lung disease

A

abpa - cf, asthmatics, eosinophilia, IGE, proximal bronchiectasis
aspergilloma - tb, sarcoid
invasive - septic
steroids and antifungals for abpa
can cause tracheal deviation and haemoptysis if massive aspergilloma

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21
Q

obstructive sleep apnoea

A

4 week referral in comorbidities, affecting work - sleep clinic
epworth sleepiness scale

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22
Q

hypoglycaemia

A

sepsis, adrenal insufficiency, alcohol
short synacthen, cortisol
ffa’s
two hypoglycaemia requqiring help - no licence
avoid choc

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23
Q

bph

A

obesity, afrocaribbean
5a redcutase - finasteride (test to dihydrotest inhi)
phosphodiesterase-5
anticholinergic - tolterodine, oxybutinin
acute retention - cathter
TURP, TUIP
REZUM - use vapour,
HoLEP - laser - bigger prostate
glycine –> ammonia toxicitiy

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24
Q

mastittis/ breast abscess

A

12-24 no improvment
I&D - diagnostic and therapeutic

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25
Q

infectious mono

A

palatal petachiae
posterior cervical lymph
burkitt’s, gbs
monospot in rapid point of care
LFTs - affects liver
atypical lymphocytes of blood film

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26
Q

rhinosinusitis

A

12 weeks
back up abx
smelly discharge

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27
Q

cataracts

A

hypocalcaemia
dex and chlormaphenicol, reading glasses
retinal detach, posterior capsule opacification
endolphthalmitis

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28
Q

optic neuritis

A

sarcoid, lupus
red desat, central scotoma, like looking through clouds, RAPD

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29
Q

vWD

A

type 3 is AR
epistatxis, menorrhagia
APTT and bleeding time prolonged
desmopressin
tranexamic acid for minor bleeding

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30
Q

neutropenic sepsis

A

<0.5 x10^9
prophyalxis - fluoroquinolone
tx: tazocin, if no imp meropenem. venc if no ikmrpovement after few days - fungal cause ix

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31
Q

pressure sores

A

type 1: non blanching erythema
2: blister - dermins/ epdiemris
3: subcut
4: necrosis of msucle, bone .etc.
Waterlow score - nutrition, bmi - screen likelihood of presure sores
nutrition, fluids, analgesia, debridement

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32
Q

psoriasis

A

subungal hyperkeratosis
guttate - strep, tear drop
eyrhtrodermic
pustular - also emegency
topical steroids + vit d
alcohol, beta blockers, trauam worsens
4 week break between steroids

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33
Q

syphilis

A

jarish heixhmer - steroid 24 hours before to prevent - fever, chills, headache
uveitis in secondary
lighning pains
argyll robertson pupil – small irregular pupils contrists on convergence not direct light

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34
Q

carpal tunnel

A

wasting of thenar
amyloid, sarcoid, ra
normal reflexes

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35
Q

septic arthritis

A

2 weeks IV then oral 4 weeks
e coli in elderly
prostehtic orhto in theatre
gonorrhoea in young men
aspirate ebfore abx

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36
Q

barrett’s

A

metapalsia: 3-5 years surveillnce and PPI
high grade: radioalblation + mucosal resection + PPI
low grade: mucosal resection + PPI

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37
Q

pulm ht

A

loud s2 hs
grham steel murmur - pulm regurg
tricuspid regurg
right heart catheterisation

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38
Q

hungitnton’s

A

lability
atrophy of striatum and butterfly dilatation of ventricles

39
Q

spinal cord compression

A

LMN at level
cauda is LMN, can be asymmetrical
sciatica
urinary retention
16mg dex
mets to bone - thyroid, breats, lungs, prostate

40
Q

diabetes insipidus

A

hypernatraemia
sarcoid for cranial
nephro - hypercalcawmiea, ckd
rule out hypercalcameia, glycemia, hypo potassium
<300 urine osmallaity
nsaids and thiazides for nephjrogenic
monitor hyponatraemia with vasopressin
body weights during water deprivation

41
Q

hyperparathyrodiism

A

primary - give vit d after
secondary - phosphate binders (sevelamar) before then calcium and vit d
tertiary - cinacalcat
familial hypocalciuric hypercalcaemia - low urine (24 hr urine colelction)

42
Q

hypoparathyrodiism

A

thyroid surgery
calcirtirol
pseudohypo - resistant to pth, high pth, low calcium, high phosphate
psuedopseudo is normal biochem

43
Q

siadh

A

demeclocycline + tolvapton
if seizure s- coma hypertonic 3% saline
hyponat signs - N+V, seizures, confusion
SAH, TB, trauma, antipsychotics .etc.
glucose, lipids, proteins rule out pseudonyponatrameia
tfts , cortisol
central pontine myelinolysis

44
Q

renal artery stenosis

A

fibromuscular dysplasia
renin high
transluminal angioplasty choelstrrol cvd rf’s control
acute flashpulm oedema
refractory hypertension

45
Q

urinary incontiencne

A

pessaires, fascial sling, colposuspension
overflow - constipation

46
Q

varicocoele

A

enlargement of testicular veins
embolisation, surgery
valsalva manouvres

47
Q

pad

A

<0.9, <0.5, <0.3
angioplasty in critical limb short lesions
>10cm = open surgery bypass
embolectomy after opioids and unfractionated heparin in acute limb
<20 beurgers
calf - fermoral
buttocks - ilial
* Leriche Syndrome (aortoiliac occlusive disease)
○ Buttock claudication
○ Impotence, erectile dysfunction
Absent/weak distal pulses

48
Q

hus ttp

A

aki, maha, thrombocvytopaenia
bloody diarhooea
haemodialysis
nromal clotting

49
Q

polycythaemia

A

aspirin
hepatosplenomegaly, ht
smoking
aml

50
Q

aspirin

A

hypokalaemia
ecg
1 hr - activated charcoal
clotting - pt prolonged
slaocylate levels
IV potassium chloride, sodium bicarb and fluids
monitor for renal failure -pulm oedema

51
Q

opiate

A

400mg naloxone
resp acidosis

52
Q

paracetmaol

A

hypoglycaemia
if malnourished, signs of ruq even if <4hours IV nacetyl
otherwsie wait as peak at 4 hours
<1 - activated chasrcoal
King’s college: pH<7.3, PT >100, enceohalopathy, creatinine
mx 2x500, 4 in 24 hrs

53
Q

sepsis

A

qsofa score 2 or more - high rsik
RR > 22, altered mental state, hypotension - sbp <100

54
Q

cutaenous warts

A

keratanised: imiqumod
non: podophyllin
6, 11
gardasil
HBV, syphillis, HIV

55
Q

hyeprcalcaemia of malig

A

addisons, sarcoid, paget’s rule out
thiazides, milk alklai also rule out

56
Q

ibs

A

isphagula hsuk - fybogel
>6months
blaoting
ssri’s - cosmntipation dom, amitryptilline for diarrhoea dom
cbt
passage of mucus
antispasmodics - peppermnt oil

57
Q

hepatocellular carcinoma

A

jaundice
aflatoxins - aspergillus flavus
ruq mass
biopsy between ribs

58
Q

pilonidal sinus

A

forced hair isnertion into natal cleft
karydaki’s if recurrent
abscess - icision and drainage same day

59
Q

dvt

A

> 3cm
if scan -ve, d-dimer +ve, stop anticoag and repeat scan in 1 week
heparin if renal failure/ risk of bleeding
extend below knee/ cancer = 6 months
thrombophlebitis is comp
proximal leg USS within 4 hours
nephrotic syndrome
Homan’s sign

60
Q

dyslipidaemia

A

fasdting triglycerides
secondary to cushings, hypothyroid
check tfts
steroids
fundoscopy
lft 3 months then 12 months
ck >5 times upper limit
asthenia, myositis, gi distubance
qrisk - 10% not type 1, renal fialure, familial
20mg

61
Q

asbestos

A

clubbing in both
lymph, abdo pain
thoracoscopy - bloody pleural fluid
pulm rehab + oxygen therapy maybe lung transplant in asbeetsos
shipyard workers
bilateral insp crackles

62
Q

idopathic lung fibrosis

A

pirfenidone - anti fibrotic
pulm rehab, stob smoking, physio
rhf - cor pulmonale

63
Q

lung abscess

A

pseudomonas, kleb, staph
foul smelling sputum

64
Q

cns tumours

A

dex for cerebral oedema
meningioma, craniopharyngioma, oligodendroma, meningioma, glioblastoma, check cheat sheet
werncike’s - temporal
tuberous sclerosis, neurofibromatosis

65
Q

encephalitis

A

CMV, cryptococcus
cerebral fluid viral PCR
CMV - add ganciclovir and foscarnet
subacute scleroising panencephalitis
monitoring for 1 year
MRI: oedema, BBB breakdown, hyperdense lesions

66
Q

horners

A

neck pain - carotid
CT angiography for dissection
STC (central, pre, post)
stroke, syringo, ms
trauma, thyrodectomy, pancoast tumour
carotid atyery diss, cavernous sinus, cluster, carotid aneursym

67
Q

bladder cancer

A

aromatic amines, smoking
Baso low risk and non-invasive = TURBT (transurethral resection of bladder tumour)
If low risk and invading muscle = radical cystectomy
If muscle invasive and high risk and unfit for cystectomy = radiotherapy
Palliative if msucle invasive and widespread metastases
If hgih risk of recurrence = intravesical bacillus camette-guerin (BCG)
recurrent uti’s, fund symps
htn + polycythaemia
cystoscopy + biopsy

68
Q

eczema

A

patch test
tzanck test - herpes
refer if contact dermatitis
topical calcineurin inhibitors = tacrolimus

69
Q

erythema multiforme

A

CAPINTS
sarcoid malignancy
mucosal - major

70
Q

scc

A

marjolins arising for ulcer
bowen’s is SCC in situ

71
Q

malaria

A

primaquine for vivax and ovale
chloroquine for others
parasitameia >2%, severe anaemia, hypoglycaemia, acidosis = severe
rapid diagnostic tests
3 consecutive days of blood films
thrombocytopaenia

72
Q

amyloidosis

A

national amyloid centre
dexomethoasone and bortezomib
abdo fat biopsy/ rectum
periorbital purpura
macroglossia
waldenstrom macroglobulinaemia

73
Q

microcytic

A

low transferrin or normal in acd
angular stomatitis
peripehral neuropathy in lead piisoning
pencnil cells
koilonycia
pyridoxine for sideroblastic
dimercaprol for lead posioning

74
Q

macrocytic

A

phenytoin for folate
myelodysplasia, alcohols may have liver disease
hypersegmented cells
taregt - likver disease
IM hydroxocobalamin 3x a week for 2 weeks then 3 monthly lifelong

75
Q

mallory weiss

A

hyperemesis gravidarum
retching
tarry stools
CXR - rule out boerhaave’s
pneumomediastinum, emphysema, crepitus, pleural effusion in boerhaave’s

76
Q

mitral regurg

A

bromocriptine
mitral valve prolapse - mid systolic click
atrial myxoma
laterally displaced apex beat thrusting
parasternal heave

77
Q

wernicke’s

A

ammonia
bariatric, severe vomiting
glucose after thiamine
acomprosate

78
Q

men

A

AD
Men1 and 2 is RET gene
remember prolactinoma under pituiatyr
gastrinomas –> peptic ulcer

79
Q

pcos

A

eflornithine worsens acne
clomiphene
bp, lipid profile, weight

80
Q

testicular cancer

A

mumps orcvhitis
afp non seminomas
teratoma, choriocarcinoma
ldh
hydrocoele
para aortic ln’s

81
Q

end of life symps

A

chlorpromazine for hiccups
ondansetron chemo
metoclopromide gi but not bowel obstruction
ocycodone from morphone /2
to subcut dimorphine /3

82
Q

metastatic disease

A

dex for cerebral oedema, seizures
spine most common
path fractures, hyperclacaemia, alp raised

83
Q

candidiasis

A

nystatin, micoconazole
spacer
glycaemic control

84
Q

q fever

A

transaminitis
pneumonia
doxycycline

85
Q

acud base

A

stroke, sah, anxiety = resp alk
met acid = diarrhiea
met alk = vomiting

86
Q

head injury

A

<13
<15 2 hours after
new focal neurology
al within 1 hr

8 hours - bleeding, <15, dangerous mech

87
Q

hypothermia

A

osborne waves, j waves
prolonged qt
avoid iv drugs
ecg, abg, glucose, haematocrit

88
Q

malignant hyperthermia

A

dantrolene
ca2+ release
suxamethonium

89
Q

lyme disease

A

meningitis, facial palsy, heart block, ericarditis
ELISA, repeat 4-6 weeks later if -ve
if symptoms persist at 12 weeks do immunoblot
28 days doxy
IV ceftriaxone 2-4 weeks if does not resolve

90
Q

osteomalacia

A

looser’s zones and pseudofractures

91
Q

psoriatic

A

psarc score
arthritis mutilans, spondylitis, dip preodminant

92
Q

path fractures

A

pagets, osteo, parathyroid, mets and primary bone tumours

93
Q

spinal fractures

A

wedging of vertebra on x-ray

94
Q

breast cancer referrals

A

Breast cancer in a first-degree male relative of any age
Breast cancer in a first-degree relative under the age of 40
Bilateral breast cancer in a first-degree relative under the age of 50
Breast cancer in two first-degree relatives

95
Q

ra das score

A

DAS scores of >5.1 indicate high disease activity and the recommendation is to escalate therapy and to consider biologic therapy if eligible