Week 3 Flashcards

1
Q

People who get Opportunistic fungal infections

always found on the body

A
  1. Diabetic
  2. Malignancies (adv.)
  3. Radiation
  4. Immunosuppressed
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2
Q

Do opprotunistic fungal infections perforate the palate like Deep fungal infections?

A

Yes

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3
Q

Anachoresis occurs in Opprotunistic fungal infections?

A

Yes (true)

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4
Q

Opprotunistic fungal infections

  • Which are shaped as L
  • Which as Y
A

L is Aspergillosis

Y is Mucormycosis (Phy)

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5
Q

What is the treatment for Opprotunistic fungal infections

A

Amphotericin B

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6
Q

3 most common Immunologic diseases

A
  1. Aphthous ulcers
  2. Drug reaction
  3. Erythema Multiforme
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7
Q

Aphthous Ulcers

-What predisposes one to them? (4)

A
  1. Women
  2. Allergies
  3. Stress
  4. Acidic Foods
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8
Q

At what rate in a year would one be concerened about RECURRENT Aphthous ulcers having a systemic underlying CAUSE?

A

5-6 in SAME location in a Year.

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9
Q

What are some systemic implication for RECURRENT aphthous ulcers? (4)

A
  1. Vitamin deficiencies
  2. Celiacs
  3. Crohn’s
  4. AIDS
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10
Q

Three types of Aphthous ulcers? (3)

A
  1. Minor
  2. Major
  3. Herpetiform
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11
Q

Characteristics of minor Aphthous Ulcers?

-size, shape, Number, location

A

size-0.5 cm
Shape-oval
Number-1to5
Location-Mucosa (mobile non-keratinized)

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12
Q

Characteristics of minor Aphthous Ulcers?

  • Pain
  • Scarring
A

Moderate to mild Pain

No scarring (primary healing)

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13
Q

Characteristics of Major Aphthous ulcers?

-size, shape, Number, location

A

Size-1.0cm
Shape-RAGGED oval
Number-1to10
Location-Mucosa (mobile non-keratinized)

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14
Q

Characteristics of Major Aphthous Ulcers?

  • Pain
  • Scarring
A

ExTREME Pain

Has scarring (secondary healing)

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15
Q

Characteristics of Herpetiform Aphthous ulcers?
-size, shape, Number, location

**PHOTO is on test (MANY little lesions!!!)

A

Size-0.5cm
Shape-oval
Number-10to100
Location-Usually not gingiva (but can be anywhere)

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16
Q

Aphthous ulcer Differencial (4)

A

HSV
Truamatic ulcers
Neutropenia
Vesiculobullous ulcers

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17
Q

Treatment of Aphthous ulcer? (4)

A

Steroids (topical or systemic)
Topical tetracycline
Debacterol–>Chemical cauterization

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18
Q

**Topical tetracycline (Low dose Doxy) Helps to differentiate Seondary HSV from aphthous ulcers, as the tetracycline is NOT effective against HSV (viral).

A

BLANK

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19
Q

Recalcitrant means?

A
Chronically Recurrent (ulcers)
-biopsy them
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20
Q

What is the cause of a recalcitrant Aphthous ulcer?

A

Crohn’s disease

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21
Q

recalcitrant Aphthous ulcer

-histopathology

A

-NON-caseating granulomas

22
Q

***Crohn’s has skip lesions (repeated endoscopes required) hard to diagnose

23
Q

Behcet’s Syndrome

  • Age
  • Sex
  • HS Type (1-4?)
A

age - 20-30
sex - males
Hypersensitivity - IV Delayed

24
Q

Behcet’s Syndrome

  • Triad of involvement (3)
  • HLA type
A
  1. Mouth
  2. Eyes
  3. Genitals
    HLA-B51
25
Behcet's Syndrome - Initial manifestation - Key systemic symptom
MAJOR 'Aphthous' ulcers (ragged ovals) -Systemic Arthritis
26
Behcet's Syndrome Treatments (2)
Steroids | Immunosuppresive medications
27
Reiter's - Age - Sex - Location
- Age 30-40 - White men - Location: Hard palate* or tongue
28
Reiter's | -Triad
1. Polyarthritis(joints) 2. Conjunctivitis(eyes) 3. Urethritis(PEEPEE)
29
Reiter's | -HLA?
HLA-B27
30
Reiter's | -Pain level?
No pain
31
Reiter's | -Treatment
NSAIDS/Antibiotics for shigella
32
Erythema Multiforme - Hypersensitivity type - Two types
- Hypersensitivity 3 (targets SMALL blood vessels) 1. Major (stevens-johnson) 2. Minor
33
Erythema Multiforme - What bring on major vs minor? - Location of Major vs minor
Major- Drugs (Oral, skin, genital, EYES) | Minor-HSV sequelae (Oral and skin only)
34
Erythema Multiforme | -What is unique about the systemic distribution of the lesions?
They are symmetrical.
35
Erythema Multiforme | -Main indicator for MAJOR vs minor
Crusting lips | -and eye involvement/Genital
36
**Erythema Multiforme can not be differenciated using DIF testing (no antibodies are pathognomic)
BLANK
37
Erythema Multiforme | -Differential (4)
1. HSV 2. Aphthous 3. PV/MMP 4. EROSIVE Lichen planus
38
Erythema Multiforme | -Treatment
Steroids | -and treat sypmtoms
39
What Antibody is active for Adverse Drug Reactions (ADR'S)
IgE
40
What is Major symptom of ADR's?
Angioedema
41
Angioedema | -Causes of angioedema (3)
1. Hereditary (Loss of C1 esterase) 2. ACE inhibitor (drug rxn) 3. Contact allergy (latex)
42
Differential for Lichenoid Mucositis (5)
1. Lichen planus 2. Red and white Plakia 3. MMP and PVulgaris 4. Erythema Multiforme 5. Aphthous
43
Stomatitis Medicamentosa
Allergic rxn to systemic drugs (FAST) Dangerous | ?Probs Type 1 hypersensitivity
44
Stomatitis Venenata A.K.A=Contact Mucositis | -Type HS?
Allergic reaction via Direct skin contact | -Type 4 hypersensitivity
45
**Plasma cell GIngivitis is a contact Mucositis
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46
Wegener's Granulomatosis | -3 types
1. Classic 2. Limited 3. Superficial
47
Wegener's Granulomatosis | -Triad (which TYPE does the tirad apply to?)
1. Upper/lower respiratory 2. Skin 3. Renal - --Classic Wegener's
48
Wegener's Granulomatosis | Primary oral Finding?
Strawberry gingivitis | ***IT is a vasculitis
49
Wegener's Granulomatosis | -Problem with Strawberry GING (2)
- Destruction of underlying bone | - --Also causes Ging hyperplasia
50
Wegener's Granulomatosis | -What is pathognomic for wegeners?
a POSITIVE cANCA test
51
Wegener's Granulomatosis | -Treatment
Immunosuppresion | -chemo
52
****Tcell lymphoma will perf the palate. Duh
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