Week 3 Flashcards

(34 cards)

1
Q

what are relative contraindications for NiPPV?

A
  1. dec LOC
  2. Lack of resp drive
  3. Incr secretions,
  4. Hemodynmaic instability
  5. Facial trauma
  6. Cardiac arrest
  7. Other risks for aspiration
  8. Need to intubate - unless using Bipap to pre-oxygenate
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2
Q

For bipap what is a starting pressure?

A

10/5

IPAP/EPAP

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3
Q

what is the maximum IPAP you should give someone on BLPAP

A

20 cmH2O - overcomes esophageal sphincter and can cause gastric insufflation

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4
Q

when should abg be done after intubation and what is one of its main uses?

A

15-20 minutes after intubation to compare ETCO2 with PaCO2

ABG generally correlates well with ETCO2 (PaCO2 may be 5-10 mmHg higher)

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5
Q

Does pH of arterial samples correlate with VBG?

A

yes unless critically ill in which case vbg is less reliable

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6
Q

Does CO2 in arterial correlate with venous?

A

Correlation is less reliable. ABG better.

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7
Q

what does PIP (peak inspiratory pressures) represent?

A

Airway resistance, lung compliance and resistance of the circuit itself

Circuit resistance, airway resistance, Lung compliance.–> this is only in VCV

PIP therefore in VCV is not reflective of alveolar pressure.

In PCV PIP is a reflection of aveolar pressure.. dang.

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8
Q

how are PPlat measured?

A

Pressure measured on inspiratory hold

it represents maximal end inspiratory alveolar pressure in VCV

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9
Q

What is the likely cause?

Pt intubated, then notice decreases in lung pressure

A

Ventilatory circuit leaks or disconnection from circuit or unintended extubation

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10
Q

Recent ED-based data have demonstrated that the use of rocuronium during rapid sequence intubation (RSI) is associated with increased time to adequate sedation, as well as decreased overall dose of sedation, when compared to patients intubated with succinylcholine

A

Gasp!

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11
Q

what is an indication NMBA use again after RSI?

A
  1. If patient asynchrony/tense patient – need to sedate and paralyse
  2. ARDS - use of NMBA has been assoc with shorter duration of ventilation and improved mortality
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12
Q

Does impaired hepatic or renal function increase duration of paralysis?

A

it may yes.

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13
Q

in obese pts and those with renal and hepatic insuff why are benzo’s not ideal for sedation post intuabtion?

A

tissue accumulation and prolonged sedation

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14
Q

What is a calculation for IBW?

A

men = 50 + 2.3 (height in inches - 60)

women = 45 + 2.3 (ht -60)

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15
Q

what is a good starting peep for COPD?

A

5 cm H20

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16
Q

why should we avoid NMBA in COPD patients?

A

NMBA with the combination of steroids puts pts at higher risk for critical illness polymyopathy

17
Q

With ARDS development what 2 things confer mortality benefit?

A

Vt 5-6 cc/kg

Pplat <31 cm H2o

18
Q

In neonates and infants what is the abx choice for empiric coverage and why would you add vanco?

A

Cefotaxime50 mg/kg q 8 hours plus ampicillin 50-100mg/kg q 6

you would add vanco if there is suspected strep pneumoniae resistant to penicillins and cephalosporins.

19
Q

sickle cell pts are at particular risk for what condition?

A

Salmonella osteomyelitis

20
Q

A retic count in febrile sickle pt is important because many infections (ex Parvovirus B19) can induced life threatening _____

A

aplastic crisis

21
Q

In VP shunt infections what are the most common bugs?

A

Staphylococcus epidermidis then staph aureus are the usual causative organisms.

22
Q

what artery in epidural hematoma/

A

middle meningeal artery

23
Q

Epidural hematomas are a disease of the young but are rare in age<2 and elderly. why?

A

in <2 and elderly the dural is closely attached to the skull so less likely to have blood accumulation between

24
Q

What are examples of extra axial intracranial injuries and intra-axial intracranial injuries

A

Extra- axial: SDH, EDH, traumatic SAH, subdural hygroma (CSF),

Intra-axial: cerebral and cerebellar Contusion, Traumatic axonal inj, cerebral and cerebellar hematomas

25
what is the most common CT finding in severe head trauma?
traumatic SAH | tears in small subarachnoid vessels
26
whats the difference between DAI and TAI (traumatic axonal injury)
Typically its a spectrum and injury is localised. In milder cases TAI is preferred and severe DAI is ok to use
27
Is pupillary examination for localization of an intracranial lesion accurate?
Its neither sensitive or specific. can also be caused by traumatic mydriasis
28
How does a herniation syndrome lead to a dilated pupil?
ICP on CN 3 compromises the parasympathetic fibres and pupillary dilation on the affected side.
29
what does decorticate and decerebrate suggest with regards to area of injury?
decorticate - above midbrain | decerebrate - midbrain lesion
30
what is the reversal agent for warfarin?
Octaplex, | FFP, Vit K
31
What is the reversal agent for Dabigatram?
Idaricuzumab 5 g can also be dialyzed Dabigatran is a direct thrombin inhibitor
32
How would you reverse Rivaroxaban?
No reversal agent specifically --> maybe Andexanet alfa Life-threatening bleeding Consider tranexamic acid 15-30mg/kg IV then 1 mg/kg/h infusion Consider prothrombinex-VF (efficacy uncertain) 50 U/kg IV (or 8 x 500 unit vials for an average 80kg patient). Consider FEIBA 50 IU/kg (contains factors 2,7,9 an 10 in predominatly inactivated form as wellas activated factor 7 and 1-6 units of Factor VIII coagulant antigen (FVIII C:Ag) per mL)
33
PEEP is thought to incr ICP by decreasing venous return. How do we mitigate this
Ensure adequate volume resuscitation, and MAP and PEEP does not adversely affect ICP. may improve by improving oxygenation
34
what is the most common dysrythmia after TBI?
SVT | Dysrythmias tend to resolve with improved ICP