Week 3 Flashcards
(1 cards)
1
Q
How is nonhaem absorbed
A
Non haem iron is released from food stuffs by acid digestion and proteolytic enzymes in stomach .
It must be reduced from ferric to ferrous form by duodenal cytochrome B1 .
This process in influenced by vitamin C .
Iron fe 2+ is taken into the enterocyte through the divalent meta transporter DMT 1 . DMT 1 is an electrogenic pump . It’s expression is upregulated in iron deficiency .
Iron is exported from the enterocyte to the circulating plasma through ferroportin/hepcidin
