Week 3: Axial Skeleton Flashcards
(87 cards)
Describe the skeletal system
- System of protection and support composed primarily of bone and cartilage
- Also consists of joints and ligament
- Accounts for about 20% of body mass
- Bones make up most of the skeleton.
- Cartilages occur only in isolated areas, such as the nose, parts of the ribs, and the joints.
- Ligaments connect bones and reinforce joints, allowing required movements while restricting motions in other directions.
- Joints provide for the remarkable mobility of the skeleton.
Describe cartilage (11 points)
- The human skeleton is initially made up of cartilages and fibrous membranes but bone soon replaces most of these early supports.
- A skeletal cartilage is made of some variety of cartilage tissue sculpted to fit its body location and function.
- Cartilage consists primarily of water. It is very resilient—it has the ability to spring back to its original shape after being compressed.
- Cartilage contains no nerves or blood vessels. It is surrounded by a layer of dense irregular connective tissue called the perichondrium, which contains blood vessels that nourish the cartilage cells.
- The perichondrium also acts as reinforcement to resist outward expansion when the cartilage is compressed.
- The thickness of cartilage is limited by the distance nutrients can diffuse through the matrix to reach the cells.
- Three types of cartilage:
1. Hyaline cartilage: the most abundant cartilage type in the body; provides firm support with some pliability
2. Elastic cartilage: cartilage with abundant elastic fibers; more flexible than hyaline cartilage
3. Fibrocartilage: the cartilage most resistant to compression and stretch. Forms vertebral discs and knee joint cartilages - All three types have the same basic components—cells called chondrocytes, enclosed in small cavities (lacunae) within an extracellular matrix containing a jellylike ground substance and fibers.
Describe Hyaline Cartilages (8 points)
- provide support with flexibility and resilience.
- They are the most abundant skeletal cartilages.
- Their chondrocytes are spherical and the only fiber type in their matrix is fine collagen fibers (which are undetectable microscopically).
- Types of skeletal hyaline cartilages include:
- Articular cartilages, which cover the ends of most bones at movable joints
- Costal cartilages, which connect the ribs to the sternum (breastbone)
- Respiratory cartilages, which form the skeleton of the larynx (voice box) and reinforce other respiratory passageways
- Nasal cartilages, which support the external nose
Describe Elastic Cartilages (2 points)
- Resembles hyaline cartilages, but they contain more stretchy elastic fibers and so are better able to stand up to repeated bending.
- They are found in only two skeletal locations—the external ear and the epiglottis (the flap that bends to cover the opening of the larynx each time we swallow)
Describe Fibrocartilage (3 points)
- Highly compressible with great tensile strength
- Consists of roughly parallel rows of chondrocytes alternating with thick collagen fibers
- Fibrocartilages occur in sites that are subjected to both pressure and stretch, such as the padlike cartilages (menisci) of the knee and the discs between vertebrae
Locate the major cartilages of the adult skeleton (20 points)
Describe how cartilage grows (6 points)
- Unlike bone, which has a hard matrix, cartilage has a flexible matrix that can accommodate mitosis.
- It is the ideal tissue to use to rapidly lay down the embryonic skeleton and to provide for new skeletal growth.
- Cartilage grows in two ways.
1. Appositional growth: cartilage-forming cells in the surrounding perichondrium (the surrounding connective tissue) secrete new matrix against the external face of the existing cartilage tissue.
2. Interstitial growth: the lacunae-bound chondrocytes divide and secrete new matrix, expanding the cartilage from within. Typically, cartilage growth ends during adolescence when the skeleton stops growing. - Under certain conditions—during normal bone growth in youth and during old age, for example—cartilage can become calcified (hardened due to deposit of calcium salts). Note, however, that calcified cartilage is not bone; cartilage and bone are always distinct tissues.
Describe the differences between cartilage and bone (5 points)
- Connective tissue: cartilage is surrounded by perichondrium, bone is surrounded by periosteum
- Blood vessels and nerves: cartilage has no blood vessels or nerves while bone has both throughout
- Composition : cartilage is composed of chondrocytes in lacunae, bones is made up of osteocytes in lacunae
- Extracellular Matrix: cartilage has a flexible extra cellular matrix made by chondroblasts, bone has rigid extracellular matrix (due to inorganic calcium salts) whose organics part is made by osteoblasts
- Growth: cartilage grows through appositional growth and interstitial growth, bones grows only through appositional growth
Describe the functions of the skeleton and of bone tissue. (12 points)
- Bones perform seven important functions
1. Support: Bones provide a framework that supports the body and cradles its soft organs. - For example, bones of lower limbs act as pillars to support the body trunk when we stand, and the rib cage supports the thoracic wall.
2. Protection: The fused bones of the skull protect the brain. - The vertebrae surround the spinal cord, and the rib cage helps protect the vital organs of the thorax.
3. Anchorage: Skeletal muscles, which attach to bones by tendons, use bones as levers to move the body and its parts. As a result, we can walk, grasp objects, and breathe. - The design of joints determines the types of movement possible.
4. Mineral Storage: Bone is a reservoir for minerals, most importantly calcium and phosphate. - The stored minerals are released into the bloodstream in their ionic form as needed for distribution to all parts of the body. Indeed, “deposits” and “withdrawals” of minerals to and from the bones go on almost continuously.
5. Blood cell formation: Most blood cell formation, or hematopoiesis, occurs in the red marrow of certain bones
6. Triglyceride (fat) storage. Fat, a source of energy for the body, is stored as yellow marrow in the cavities of long bones.
7. Hormone production. Bones produce osteocalcin, a hormone that helps to regulate insulin secretion, glucose homeostasis, and energy expenditure
Describe the classification of bones (4 points)
- Bones are divided into two major groups
1. The axial skeleton forms the long axis of the body and includes the bones of the skull, vertebral column, rib cage, hyoid bone and ossicles. Generally speaking these bones protect, support, or carry other body parts.
2. The appendicular skeleton consists of the bones of the upper and lower limbs and the girdles (shoulder bones and hip bones) that attach the limbs to the axial skeleton. Bones of the limbs help us move from place to place (locomotion) and manipulate our environment. - Bones are also classified by their shape as long, short, flat, or irregular
Describe long bones (5 points)
- Long bones, as their name suggests, are considerably longer than they are wide.
- A long bone has a shaft plus two ends, which are often expanded.
- All limb bones except the patella (kneecap) and the wrist and ankle bones are long bones.
- Notice that these bones are named for their elongated shape, not their overall size.
- The three bones in each of your fingers are long bones, even though they are small.
Describe short bones (4 points)
- Short bones are roughly cube shaped. The bones of the wrist and ankle are examples.
- Sesamoid bones a special type of short bone that form in a tendon (for example, the patella).
- They vary in size and number in different individuals.
- Some sesamoid bones act to alter the direction of pull of a tendon. Others reduce friction and modify pressure on tendons to reduce abrasion or tearing. Many influence the action of muscles.
Describe flat bones (2 points)
- Flat bones are thin, flattened, and usually a bit curved.
- The sternum (breastbone), scapulae (shoulder blades), ribs, and most cranial bones of the skull are flat bones
Describe irregular bones (2 points)
- Irregular bones have complicated shapes that fit none of the preceding classes.
- Examples include the vertebrae and the hip bones
Describe the gross anatomy of bones (3 points)
- Every bone has a dense outer layer that looks smooth and solid to the naked eye. This external layer is compact bone.
- Internal to this is spongy bone (also called trabecular bone), a honeycomb of small needle-like or flat pieces called trabeculae.
- In living bones the open spaces between trabeculae are filled with red or yellow bone marrow.
Describe the gross anatomy of a flat bone (5 points)
- Short, irregular, and flat bones share a simple pattern: They all consist of thin plates of spongy bone (diploë) covered by compact bone.
- The compact bone is covered outside and inside by connective tissue membranes, respectively the periosteum and endosteum.
- However, these bones are not cylindrical and so they have no shaft or expanded ends.
- They contain bone marrow (between their trabeculae), but no well-defined marrow cavity.
- Where they form movable joints with their neighbors, hyaline cartilage covers their surfaces.
Describe the gross anatomy of a long bone. (8 points)
- With few exceptions, all long bones have the same general structure: a shaft, bone ends, and membranes
- Components of a long bone are:
1. Diaphysis: elongated shaft of a long
2. Epiphyses: the end part of a long bone
3. Epiphyseal line: an epiphyseal plate that has been ossified
4. Periosteum: fibrous connective tissue membrane that covers the external surface of all bones
5. Endosteum: fibrous connective tissue membrane that covers the internal surface of all bones
6. Blood vessels and nerves
Describe the diaphysis (4 points)
- A tubular diaphysis, or shaft, forms the long axis of the long bone.
- It is constructed of a relatively thick collar of compact bone that surrounds a central medullary cavity, the central cavity of a long bone.
- Also known as the marrow cavity, this cavity contains no bone tissue. Instead, the medullary cavity contains yellow marrow (fat) in adults and so is called the yellow marrow cavity.
- Between the marrow and the compact bone, there is often a thin layer of spongy bone.
Describe the epiphyseal line (3 points)
- Between the diaphysis and each epiphysis of an adult long bone is an epiphyseal line, a remnant of the epiphyseal plate.
- The epiphyseal plate, commonly called the growth plate, is a disc of hyaline cartilage that grows during childhood to lengthen the bone.
- The flared portion of the bone where the diaphysis and epiphysis meet, whether it is the epiphyseal plate or line, is called the metaphysis
Describe the epiphysis (3 points)
- The epiphyses are the bone ends.
- An outer shell of compact bone forms the epiphysis exterior and the interior contains spongy bone.
- A thin layer of articular (hyaline) cartilage covers the joint surface of each epiphysis, cushioning the opposing bone ends during movement and absorbing stress.
Describe the periosteum (7 points)
- A glistening white, double-layered membrane called the periosteum covers the external surface of the entire bone except the joint surfaces.
- The outer fibrous layer of the periosteum is dense irregular connective tissue.
- The inner osteogenic layer next to the bone surface contains osteoprogenitor cells (primitive stem cells that give rise to most bone cells).
- It also has bone-destroying cells (osteoclasts) and bone-forming cells (osteoblasts).
- The periosteum is richly supplied with nerve fibers and blood vessels, which is why broken bones are painful and bleed profusely.
- Perforating fibers—bundles of collagen fibers that extend into the bone matrix—secure the periosteum to the underlying bone.
- The periosteum also provides anchoring points for tendons and ligaments. At these points the perforating fibers are exceptionally dense.
Describe the endosteum (3 points)
- A delicate connective tissue membrane called the endosteum covers internal bone surfaces.
- The endosteum covers the trabeculae of spongy bone and lines the canals that pass through the compact bone.
- The endosteum contains the same cell types as the inner layer of the periosteum.
Describe the blood vessels and nerves in the long bone (6 points)
- Unlike cartilage, bones are well vascularized.
- The main vessels serving the diaphysis are a nutrient artery and a nutrient vein.
- Together these run through a hole in the wall of the diaphysis, the nutrient foramen.
- The nutrient artery runs inward to supply the bone marrow and the spongy bone. Branches then extend outward to supply the compact bone.
- Several epiphyseal arteries and veins serve each epiphysis in the same way.
- Nerves accompany blood vessels through the nutrient foramen into the bone.
Label the image (18 points)