Week 3 (exam 1) Flashcards
Methotrexate
DMARDs (disease modifying antirhumatic drug)
Rheumatoid arthritis
autoimmune reaction that effects the synovial tissue causing loss of articular surfaces and joint motion
Symptoms of rheumatoid arthritis
Symmetric joint pain/morning stiffness
Swelling
Warmth
Erythema
Low grade fever
Lack of function
Stages of RA
Stage 1
- the body mistakenly attacks its own joint tissue
Stage 2
- the body make the antibodies and the joints start swelling up
Stage 3
- the joints start becoming bent and deformed, the fingers become crooked. These misshapen joints can press on nerves and cause sever pain
Stage 4
- if not treated the disease will progress into the last stage, in which there’s not joint remaining at all and the joint is essentially fused
Extra Articular features of RA
Weight loss
Fatigue
Anemia
Lymph node enlargement
Raynaud’s phenomenon
Arteritis (inflammation of the arteries)
Neuropathy
Pericarditis
Sjogren’s syndrome (dryness throught the body)
Sjogren’s syndrome
a chronic autoimmune disorder that primarily affects the glands that produce moisture, such as the salivary and lacrimal glands
Assessment findings of RA
Joint inflammation
Tenderness
Temperature changes in joints
Extra articular changes
Lab findings in RA
Rheumatoid factor
Anti-CCP (cyclic citrullinated peptide antibodies)
ESR and CRP
CBC – (baseline)
arthrocentesis
X- ray
Medical management of early RA
Balance of rest and exercise
NSAIDs
DMARDs
Biologic DMARDs
DMARDs
a class of medication used to treat inflammatory and autoimmune diseases
Ex: methotrexate
leflunomide hydroxychloroquine
sulfasalazine
can cause N/V, diarrhea, hair loss, fever, increased risk of infection, lymphoma, kidney damage, and can cause bone marrow suppression
Biologic DMARDs
Rituximab
Etanercept
Adalimumab
Sarilumab
can increase risk of infection
Established RA
Formal occupational and physical therapy program
Addition of an immunosuppressant
Reconstructive surgery
Corticosteroids
Anti depressants
Nutrition
Assessment of pt with a Rheumatic disease
current and past symptoms
patient’s psychological and mental status
social support systems,
ability to participate in daily activities,
compliance with treatment regimen
management of self-care
systemic lupus erythematosus
chronic inflammatory disorder of the connective tissue and it caused wide spread inflammation as well as tissue damage
systemic lupus erythematosus symptoms
Arthralgias (joint pain) and arthritis
Skin manifestations
Pericarditis
Renal involvement
CNS involvement
impacts females more than males
see grid in notes
Dx for systemic lupus erythematosus
- labs will reveal moderate to severe anemia, thrombocytopenia, leukopenia, and positive antinuclear antibodies
- classic sign is the butterfly rash
Medical management of lupus is
Pharmacologic therapy
Corticosteroids
Antimalarials (hydroxychloroquine)
NSAIDs
Immunosuppressants
Monoclonal antibodies
Nursing management of lupus is
- educate pt to avoid sun exposure
- due to the involvement of multiple organ systems, educate pts about the importance of periodic health screenings
- provide support groups
- educate on the importance of sticking to their medication regimen
Causes of thyroid cancer
radiation exposure
3/4 of cases are female
Dx of thyroid cancer
Large or palpable thyroid
Ultrasound, MRI, CT
Thyroid function test
Serum Ca and phosphorous levels
Biopsy once ultrasound confirms mass
Radioactive iodine uptake studies
Signs and symptoms of thyroid cancer
- lesions on thyroid
- recurrent nodules on thyroid
- dysphagia
- hoarseness
- dyspnea
Tx of thyroid cancer
Thyroidectomy
Radioactive Iodine (no chemo)
Thyroidectomy
Depending on where it is, if its to the side it could be a partial
Radioactive iodine
Prior to taking this pill pt will go on a low iodine diet for two weeks (no red meat)
This will cause the thyroid to be craving iodine so that when the pt takes the radioactive iodine pill the thyroid will soak it all up.
Pts taking this pill should…
- flush toilet twice
- no pregnant visitors
- no bed sharing
- wash clothes separate