WEEK 3: Health Economic Evaluation Flashcards

1
Q

Outline the Objectives of Health Systems.

A
  • To improve the level and distribution of health outcomes in the
    population
    – Increase length of life
    – Improve quality of life
  • To protect ind
    healthcare
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2
Q

Q: How do economists view health care production?

Q: What are some important factors that influence health at a population level?

A

A: Economists view health care production as a “Health Production Function,” which is similar to a general production function. In this framework, health is considered the output, and inputs such as hospital stays, doctor visits, drugs, and other factors contribute to the production of health.

A: At a population level, factors beyond medical care, known as the social determinants of health, play a significant role. These factors can include diet, lifestyle, income, and other social and environmental factors.

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3
Q

Q: How do individuals make trade-offs between health and other economic goods?

Q: What is the concept of “derived demand” in the context of medical care?

A

A: Individuals often make trade-offs between investing in their health and allocating resources to other economic goods. The doctor acts as the patient’s agent in organizing and advising on this process.

A: The demand for medical care is considered a “derived demand” because it is derived from the demand for health. As individuals seek to improve their health, they demand medical care as a means to achieve that goal.

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4
Q

Define the following terms:

  • Efficiency:
  • Health system efficiency:
A
  • Efficiency: use resources in the best possible way to achieve certain outcomes
  • Health system efficiency: the extent to which the inputs to the health system (e.g., resources) are used to achieve health system goals.
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5
Q

Q: What is technical efficiency in the context of health and medical care production?

Q: Can you provide examples of technical efficiency in health and medical care production?

A

A: Technical efficiency refers to the ability to produce a given level of output while minimizing the use of inputs. It focuses on minimizing costs for a given level of output and reducing waste by optimizing the use of resources in producing the desired outcome.

A: Examples of technical efficiency in health and medical care production include:

*Choosing between keeping patient records in paper form or electronic form, considering factors such as cost, accessibility, and efficiency of information management.

*Using a lower dose of a drug to achieve the same clinical outcome as a higher dose, thereby minimizing the use of resources while maintaining effectiveness.

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6
Q

Q: What is allocative efficiency in the context of health and medical care production?

Q: Can you provide an example of a decision related to allocative efficiency in healthcare?

A

A: Allocative efficiency focuses on directing limited resources towards producing the “right” mix of healthcare outputs. It involves making decisions about resource allocation to maximize health gains or achieve higher social welfare from a given resource endowment.

A: An example of a decision related to allocative efficiency in healthcare is whether the government should fund a primary care service or expand a critical care unit in a hospital.

This decision involves considering the allocation of resources to different healthcare services and determining which option would result in the greatest overall health benefit or social welfare.

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7
Q

Q: What is health economic evaluation?

A

A: Health economic evaluation involves comparing two or more alternative health interventions, treatments, or programs in terms of their costs and effectiveness.

The effectiveness is measured in the same units, and the costs refer to the value of resources involved in providing the treatment or intervention.

The goal is to assess the cost-effectiveness or cost-benefit of different healthcare options.

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8
Q

Q: What are some examples of health outcomes measured in health economic evaluation?

Q: How does health economic evaluation help decision-making?

A

A: Health outcomes measured in health economic evaluation can include the number of prevented diseases and deaths, quality-adjusted life years (QALYs), disability-adjusted life years (DALYs), increased quality of life, and saved money.

A: Health economic evaluation provides information to support decision-making when resources are limited.

It helps identify the most cost-effective interventions or programs and can inform resource allocation decisions.

By comparing costs and consequences, decision-makers can prioritize interventions that provide the greatest health benefits for a given resource investment.

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9
Q

Outline Healthcare Interventions as Technologies

A

Healthcare Interventions as Technologies
* Technology is the practical application of knowledge
* Healthcare Technology and Examples
➢Drugs e.g Cisplatin
➢Vaccines e.g HPV vaccine for carcinomas
➢Medical devices e.g Pleurx-Denver catheter for fluid drainage in lung cancer
➢Diagnostics e.g CT scan screening, X-rays, Endobronchial US
➢Procedures (medical) e.g Psychotherapy for (some) cancer patients, Radiotherapy, Proton
therapy, Photodynamic therapy etc. for lung cancer
➢Procedures (surgical) e.g Laser surgery to unblock airway, cryosurgery (to freeze tumor), etc.
➢Support systems e.g Telemedicine, drug formularies, blood banks, electronic medical records
➢Health system innovations e.g Organizational and managerial e.g., clinical pathways, alternative
healthcare configuration

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10
Q

Discuss the Rationale for Economic Evaluation
in healthcare.

A
  • Information on efficacy and effectiveness is necessary but not sufficient for making healthcare decisions
    –Given scarce resources, policymakers need a means to allocate
    resources between competing demands
    – Explicit consideration of the opportunity cost of alternative courses of action is necessary
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11
Q

Q: What is comparative analysis in healthcare?

Q: What are some commonly used measures of effectiveness in comparative analysis?

A

A: Comparative analysis in healthcare involves comparing two or more health interventions, treatments, or programs in terms of their costs and effectiveness.

It aims to assess the value of one intervention compared to another by considering the costs and health outcomes associated with each intervention.

A: The gold standard measures of effectiveness in comparative analysis are quality-adjusted life-years (QALYs) and disability-adjusted life-years (DALYs).

These measures combine both the length and quality of life to provide a comprehensive assessment of health outcomes.

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12
Q

Q: How is cost-effectiveness measured in comparative analysis?

A

A: Cost-effectiveness is typically measured by calculating the cost per DALY averted or the cost per QALY gained.

These measures allow for the comparison of the costs of an intervention to the health benefits achieved, providing insights into the efficiency of different healthcare options.

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13
Q

Q: What is the NE Quadrant in health economic evaluation?

A

A: The NE (North-East) Quadrant represents a situation where Intervention B is both more costly and more effective than Intervention A.

This scenario is common when innovative technologies increase effectiveness relative to the standard of care but come at an added cost.

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14
Q

Q: What is the ICER in health economic evaluation?

State the formula for ICER.

A

A: The ICER (Incremental Cost-Effectiveness Ratio) is a measure used in health economic evaluation to compare the value of one intervention (Intervention B) to another (Intervention A).

It is calculated by dividing the incremental change in costs by the incremental change in health outcomes.

The ICER provides a cost per unit of health outcome gained, such as cost per DALY averted or cost per QALY gained.

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15
Q

What are some examples of units used in cost?

State the units used in outcomes.

A

A: Costs in cost-effectiveness analysis are always measured and presented in currency units, such as dollars, pounds, euros, or other relevant currencies.

Health outcomes, on the other hand, can be measured in various ways but must be in the same units for comparators A and B.

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16
Q

Q: What is the threshold approach in determining if an ICER represents value for money?

A

A: The threshold approach involves comparing the ICER (cost per DALY averted or cost per QALY saved) to a predetermined threshold.

One common threshold is the country’s GDP per capita.

*If the ICER is below the threshold, the intervention is considered highly cost-effective and can be judged as providing value for money

NOTE: GDP per capita is the country’s economic output per person.

17
Q

Q: What is the benchmark interventions approach in determining if an ICER represents value for money?

A

A: The benchmark interventions approach involves citing the cost-effectiveness of a benchmark intervention that has already been adopted.

If the ICER of the new intervention is lower than the benchmark intervention, it may be considered cost-effective

18
Q

Q: What is the league tables approach in determining if an ICER represents value for money?

A

A: The league tables approach involves ranking interventions in a league table according to their ICERs.

This allows decision-makers to compare interventions based on their cost-effectiveness and prioritize resource allocation accordingly

19
Q

State the 4 Types of Healthcare Economic Evaluations

A
  • Cost-Minimization Analysis
  • Cost-Effectiveness Analysis
  • Cost-Utility Analysis
  • Cost-Benefit Analysis
20
Q

Define Cost-Minimization Analysis (CMA).

A
  • CMA is used when outcomes are equal or assumed to be equal
    – Purpose of the analysis is to identify the least costly option
  • Historically recommended for economic evaluations of trials showing
    no statistical significance in effectiveness
21
Q

Define Cost Effectiveness Analysis (CEA).

A
  • In CEA, outcomes are measured in “natural units”
    – The outcomes are usually clinically relevant e.g., life-years, mm Hg for BP, HbA1c for diabetes, etc
  • Examines the costs of alternative approaches to achieving a specific (health) objective
    – Can be used to compare interventions to achieve the same outcomes e.g., in the same clinical indication

It can be used to compare interventions that aim to achieve the same outcomes within the same clinical indication.

By examining the ratio of the differences in costs and the differences in health effectiveness between options, CEA provides a framework to assess the cost-effectiveness of different decision options.

22
Q

Define Cost-Utility Analysis (CUA)

A

*Uses a non-financial common metric that allows comparisons across the health sector e.g., can compare different drugs or technologies

– Able to compare mortality-heavy interventions (e.g., road accidents) and morbidity-heavy interventions (e.g., mental illness)

  • Metric is a combination of length of life and quality of life:
    – Quality-adjusted life-year (QALY)
    – Disability-adjusted life-year (DALY)
  • CUAs require studies to estimate utility (for QALY measurement) or disability weights (for DALY measurement)
23
Q

Define Cost-Benefit Analysis (CBA)

A
  • (Considered to be) the most comprehensive economic evaluation
  • Places monetary values on inputs (costs) and outcomes thereby allowing comparison of projects (or interventions or investments) across the entire economy
  • In health sector, CBA allows calculation of net benefit;
  • —if total benefits exceed total costs, implement intervention
  • CBA results can indicate intervention desirability independently of a comparison to alternatives (other economic evaluation methods cannot)
24
Q

Method of Analysis, cost, measurement Outcome Measurement

  1. Cost-Minimization Analysis, $, equivalence demonstrated or assumed in comparative groups
  2. Cost-Effectiveness Analysis, $, Single “natural” unit outcome measure
  3. Cost-Utility Analysis, $, Multiple outcomes—life-years
    adjusted for quality-of-life
  4. Cost-Benefit Analysis, $, $
A