Week 4 Flashcards

(12 cards)

1
Q

mutation

A
  • change in genetic code continoual, random,
  • unpredictable enironmental; radiation, chemicals
  • mechanical: during replication or reading of the code neutral, beneficial, or deleterious (harmful)
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2
Q

mechanical- point mutation

A
  • the instructions to remove bad cholesterol
  • THE CAT AND DOG ARE SAD
  • point of mutation 15th letter
  • THE CAT AND DOG ARC SAD
  • result: may still make the protein or slight defect
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3
Q

mechanical frameshift mutation

A
  • THE CAT AND DOG ARE SAD
  • 3rd letter dropped, next letter used to form coden
  • THC ATA NDD OGA RES AD
  • cannot make protein increases chances of heart attack
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4
Q

chromosomal mutation

A
  • during meiosis
  • eg. trysomy 21- extra copy of C21
  • downs symbrone
  • not inherited
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5
Q

genetic drift

A
  • random changes/drift in allele frequencies from on egeneration to next
  • new generationis has non-responsive sample of alleles
    • population bottleneck
    • founder effect
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6
Q

bottleneck effect

A
  • in past 250k → 50
  • breeding programs → now 1000
  • alleles in new population are reduced
    • high to low diversity
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7
Q

founder effect

A
  • 5 million french canadians from a few thousand ‘founder population’ 300 years ago
    • this ‘found’ population is very different than parent population
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8
Q

gene flow

A
  • movemenet of alleles from one population to another
  • for human - admixture
  • eg. milration, movement of humans
  • eg. australia pop. 20 % has convicted ancestory
    • 162000 convicts of Great Britian sent to Australia
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9
Q

blanxced polymorphism

A
  • why do some recessive disorders like sickle cell anemia SCA reaamin in pop?
  • seems to contrary to natural selection
  • heterozygous genotype Ss
    *
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10
Q

natural selection:moths

A
  • manchester, england - 19th centrury- peppered moth
  • ligh moth- camo against lichen on tree trunks
  • coal then comes due to industralization
  • trees got darker
  • light moths not camo
    • light moths eaten more
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11
Q

envoluntary change in natural selection

A
  • a trait must be inherited to have importance in NS
  • NS cannot occur without variation in inhereited traits
  • fitness-releative mesaure that will change as enironment changes
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12
Q

extinction

A
  • NS failure to adpat/compete
  • sometimes from cataclysmic event eg. meteor
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