Week 4 Flashcards
(12 cards)
1
Q
mutation
A
- change in genetic code continoual, random,
- unpredictable enironmental; radiation, chemicals
- mechanical: during replication or reading of the code neutral, beneficial, or deleterious (harmful)
2
Q
mechanical- point mutation
A
- the instructions to remove bad cholesterol
- THE CAT AND DOG ARE SAD
- point of mutation 15th letter
- THE CAT AND DOG ARC SAD
- result: may still make the protein or slight defect
3
Q
mechanical frameshift mutation
A
- THE CAT AND DOG ARE SAD
- 3rd letter dropped, next letter used to form coden
- THC ATA NDD OGA RES AD
- cannot make protein increases chances of heart attack
4
Q
chromosomal mutation
A
- during meiosis
- eg. trysomy 21- extra copy of C21
- downs symbrone
- not inherited
5
Q
genetic drift
A
- random changes/drift in allele frequencies from on egeneration to next
- new generationis has non-responsive sample of alleles
- population bottleneck
- founder effect
6
Q
bottleneck effect
A
- in past 250k → 50
- breeding programs → now 1000
- alleles in new population are reduced
- high to low diversity
7
Q
founder effect
A
- 5 million french canadians from a few thousand ‘founder population’ 300 years ago
- this ‘found’ population is very different than parent population
8
Q
gene flow
A
- movemenet of alleles from one population to another
- for human - admixture
- eg. milration, movement of humans
- eg. australia pop. 20 % has convicted ancestory
- 162000 convicts of Great Britian sent to Australia
9
Q
blanxced polymorphism
A
- why do some recessive disorders like sickle cell anemia SCA reaamin in pop?
- seems to contrary to natural selection
- heterozygous genotype Ss
*
10
Q
natural selection:moths
A
- manchester, england - 19th centrury- peppered moth
- ligh moth- camo against lichen on tree trunks
- coal then comes due to industralization
- trees got darker
- light moths not camo
- light moths eaten more
11
Q
envoluntary change in natural selection
A
- a trait must be inherited to have importance in NS
- NS cannot occur without variation in inhereited traits
- fitness-releative mesaure that will change as enironment changes
12
Q
extinction
A
- NS failure to adpat/compete
- sometimes from cataclysmic event eg. meteor