Week 5 Flashcards

(39 cards)

1
Q

What are the 5 functions of bone?

A

Structural foundation
Mobility
Support
Protection
Storehouse for essential minerals

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2
Q

What is the end of a long bone called?

A

Epiphysis

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3
Q

What does diaphysis mean?

A

The shaft of the bone

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4
Q

What is a medullary

A

The hole in the bone

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5
Q

What is a endosteum

A

A sheeth

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6
Q

What is the matrix of bone?

A

25% water, 25% collagen and 50% crystallised mineral salts, calcium hydroxyapatite

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7
Q

Another word used for compact bone?

A

Cortical

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8
Q

Another word for spongy bone

A

Trabecular or cancellous

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9
Q

What percentage does compact (cortical) make up of the bone mass?

A

80%

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10
Q

Trabecular bone makes up what percentage of bone mass

A

20%

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11
Q

What is the periosteum

A

Vascular membrane, inner layers contain osteoblasts and osteoclasts and the outer layer is tough and fibrous.

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12
Q

What does the Haversian canal contain?

A

Blood vessels and nerves

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13
Q

What is the lunellae

A

Series of cylindrical plates arranged around a central canal

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14
Q

Lacunae

A

Strings of little cavities in which osteocytes sit

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15
Q

Canaliculi

A

Tiny network of channels which allows the lacunae to communicate. Allows for interstitial fluid to circulate through the bone and direct contact between osteocytes

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16
Q

Which type of bone withstands stress better

17
Q

What are the four types of bone cells

A

Osteogenic/osteopogenitor cells
Osteoblasts
Osteocytes
Osteoclasts

18
Q

Where are osteogenic cells found

A

Endosteum, inner layer of periosteum
Undifferentiated cells

19
Q

Where are osteoblasts found in

A

Surface of bone than in lacunae
They build the matrix and collagen fibres

20
Q

Osteoclasts

A

Clear bone cells. Biggest of the bone cells. Reabsorb dead bone cells to clear deadbry

21
Q

What are the four types of blood supply to bones

A

Periosteal arteries
Nutrient arteries
Metaphyseal arteries
Epihyseal arteries

22
Q

Where are periosteal arteries found

A

Periosteum and outer osteons of compact bone

23
Q

Where are nutrient arteries found

A

Medullary cavity and osteons of inner compact bones

24
Q

Where are metaphseal arteries found

A

Spongy bone and marrow

25
Where are epiphyseal arteries found
Spongy bone and marrow
26
Why is osteopenia worse in women
Low oestrogen levels after menopause
27
What is agenesis
Limb that does form or partially forms
28
Osteogenesis imperfecta
Genetic low collagen
29
Spina bífida
Vertebrae do not develop arches so spinal cord protrude
30
Achondroplasia
Long bones don’t grow
31
What disorders affect remodelling
Age, hormone levels, calcium and phosphate and mechanical stress
32
What nutritional problems lead to bone disorders
Rickets, scurvy and osteomalacia
33
What are some endocrine disorders that affect bones
Gigantism, acromegaly, pituitary dwarfism, hyper/hypoparathyroidism
34
The 4 stages of healing a fracture
1 hematoma formation 2 fibrocartilaginous callus formation 3 bony callus formation 4 bone remodelling
35
How long do bones bleed for?
6-8hrs
36
What is fibrocartilagenous callus formation also called?
Union
37
What happens at the fibrocartilageous callus formation stage
Fibroblasts invade pocallus and lay down collagen Chondroblasts produce fibrocartilage Lasts 3-4 months
38
What happens in formation of bony callus (consoldiation)
Osteoblasts secrete spongy bone that joins the broken ends Lasts 3-4 months
39
What happens in bone remodelling
Compact bone replaces spongy bone in the callus Surface is remodelled back to normal shape Sometimes a palpable lump Takes1 year