Week 5 Flashcards
(40 cards)
What is the history of alcohol? (3)
It has been around for a long time
We’ve been fermenting fruits throughout history
Even animals can recognize fermented fruits for their intoxicating properties
What is the prevalence of alcohol consumption in Canada? (5)
We consume a lot of alcohol, specifically in the Western world
In 2015, there was an 80% prevalence of alcohol consumption over the last year for people 15+
25-34 age group and males most prevalent
Almost 50% of those 15-18 have consumed it in the past year
Number 1 substance consumed in the past year by Canadians
What is the overall trend with alcohol consumption for youth?
There is an overall downward trend in alcohol consumption among grades 7-12 and it is lower than adults (but still high)
What is the AUDIT? (2) What are the 3 subscales of questions? What does your score mean?
Alcohol use disorder identification test
10 questions, typically used in a clinical setting as it is a short test that is easy to give to a lot of people
3 subscales of questions:
Hazardous alcohol consumption (frequency and amount)
Dependence symptoms (control)
Harmful alcohol use (psychological and physiological harm)
The score you receive determines whether you are engaging in drinking in any of the three categories and are at risk of AUD
What is the prevalence of AUD in Canada? (4)
18.1% of the general population has met the criteria for an AUD sometime in their life (6.3 million people)
3.2% for the past 12 months (1 million people)
So a lot of people qualify for an AUD
Known sex difference in that men have a significantly higher prevalence
What is the cost of AU in Canada? (2)
From a public health POV, AUD costs society billions in indirect costs (productivity loss), healthcare costs from health problems resulting, law enforcement costs from crime resulting and other direct costs
39.8 billion for SUDs in 2002, even more now with inflation
What did the Nutt study on conceptualizing, identifying and categorizing harms resulting from addictive substances do? (6)
Looked at how different substances weigh into perpetuating different kinds of harm
Addiction professionals identified 16 harm criteria and categorized types of harm
9 were related to physical, psychological and social harm to the self (mortality, dependence, impairment of mental functioning, loss of relationships)
7 related to physical, psychological and social harms to others (injury, crime, family adversities)
Rated 20 drugs on a 100 point scale based on each harm criteria
Also assessed relative importance of the criteria within each cluster and across clusters
What did the Nutt study on conceptualizing, identifying and categorizing harms resulting from addictive substances find? (4) what can it be used for?
Found that alcohol ranks highest as most harmful overall, both to self and others
Due to it being so accessible, normalized and so widely/frequently used
Found that certain drugs like meth cause mostly harm to self while drugs like alcohol cause more harm to others (high for both kinds of harm but on another level for harm to others)
Most frequent AUD harms are economic cost and injury to others
Can inform the use of interventions to prevent AUDs and regulate the sale and consumption of alcohol
According to the BPS model, why do people drink alcohol?
Combination of biology (genes, nutrition), psychological (emotions, behaviors) and social (stress, trauma, environmental)
According to positive reinforcement theory, why do people drink alcohol?
Because it is exciting and enhances your life
To get a high
According to negative reinforcement model, why do people drink alcohol?
To forget/remove painful memories
To stop me from feeling negative feelings associated with anxiety and depression
To reduce anxiety and forget worries
According to social theory, why do people drink alcohol? According to conformity theory, why do people drink alcohol?
As a way to celebrate and be sociable
Due to peer pressure and so I won’t feel left out
How does personality impact AUD severity? (3)
Certain personality traits (neuroticism, impulsivity, etc.) can lead to alcohol consumption at increased levels
This is because they lead to certain drinking motives that lead to addiction
These motives connect with risk factors (biopsychosocial) to form susceptibility and risk for addiction
How does alcohol impact the brain? (6)
Inhibitory neurotransmitters (GABA) are active throughout the brain to control neural activity and decrease communication between cells in the brain, making them less likely to fire
Another neurotransmitter in another area of the brain, glutamate, does the opposite as a general-purpose excitatory neurotransmitter than increases communication between the cells
When alcohol enters the brain, it binds to GABA receptors and makes the inhibitory signal of GABA even stronger, making us more relaxed and sedated
It activates opioid receptors that induce the release of endorphins, which then bind to receptors and on dopamine neurons in the reward centers to trigger dopamine release and pleasure/reward
Alcohol also binds to the glutamate receptors to block glutamate from exciting the cell, resulting in functioning problems like slurred speech, coordination and reaction issues
The more alcohol you drink over time, your brain will need more and more alcohol for the same effects because it will kill the receptors
What are the consequences of alcohol concerning neurodegeneration? (4)
Reduction and mutations in the production of new neurons as alcohol exposure continues
Reduction in brain systems (which can be somewhat reversed with even a short time abstaining)
Changes in the volume of brain areas associated with executive functioning and decision-making
Deficits in decision-making impairs the inhibition of impulsive behavior, contributing to further drug seeking behavior
What are the consequences of alcohol concerning withdrawal? (4)
Withdrawal is painful and people can die from it
Symptoms can appear within days of stopping and the physical ones usually stop within the week but the psychological ones last way longer
Physiological symptoms include sweating, seizures, fever and tremors
Delirium tremens is an extreme form of withdrawal that often results in hospitalization due to confusion, hallucinations, disorientation, fever, tremors, death
What are the consequences of alcohol concerning death from acute alcohol intoxication? (4)
Younger and older people are at greater risk
Alcohol poisoning results from drinking more alcohol than our bodies can handle, shutting it down
It is metabolized by the liver at a rate of about 1 drink per hour and consuming more creates intoxication
Consuming more than the body can metabolize creates alcohol poisoning, passing out and other physiological harms
What are the consequences of alcohol concerning alcohol liver disease? (2)
Mortality related
Fatty liver, alcoholic hepatitis, and cirrhosis
What are the consequences of alcohol concerning Alcoholic Korsakoff syndrome? (5)
Chronic memory disorder
Severe thiamine deficiency in the brain due to alcohol consumption
Problems learning new information
Inability to remember recent events
Long term memory gaps
What is the Low-Risk Alcohol Drinking Guidelines?
Guidelines for how much one should consume, risk factors to look out for, and other AUD factors based on research
What is the origin of cocaine use? (4)
German chemist Albert Nieman was the first to isolate cocaine extracted from cocoa leaves in 1860 (even though indigenous people had been chewing on the leaves for centuries)
It became popular in the 1880s in the medical community as an anesthetic for cataract surgery
Freud was fascinated with and addicted to cocaine and promoted it in papers as a “magical substance”
Cocaine was readily available, non-regulated and accessible, even in Coca Cola (which was so popular only whites could drink it)
What is the American Crack Epidemic of the 1980s? (5)
Cocaine was no longer readily available and it was highly regulated
This resulted in crack cocaine, which is crystallized cocaine mixed with baking soda as a way of making more money by selling cocaine without using as much actual coke
When boiled, the vapor was pure cocaine that resulted in an intense but short-lived high
Increase of CC use in major cities across the US in the 80s and 90s, resulting in an increase in crime and violence
Lead to “tough on crime” policies and the “war on drugs” led by the Kennedys
What is the legal status of cocaine in Canada? (4)
Schedule I drug under the Canadian Controlled Drugs and Substances Act (CCDSA)
Possession can result in 7 years imprisonment
Trafficking and production can result in life imprisonment
DUI of cocaine is a criminal offense
What is the prevalence of cocaine consumption and addiction? (6)
3 substances used in the past year by Canadians
In 2015, 1.3% of Canadians had used in the past year
This is much lower internationally (0.4%)
More than 2% in US and Australia
Overall decline in past-year cocaine use in Canada, especially for youths
Use is most prevalent among high risk populations (homeless, street-involved youth, younger, trauma, mental health, other drug use)