Week 5: Recorded Lectures Flashcards
(40 cards)
What is membrane potential?
The difference in electric potential between the interior and exterior of a biological cell
What creates an electrochemical gradient in a cell?
The presence of ions inside and outside the cell
Charge of inside cell
Negative
Charge of outside cell
Positive
How is membrane potential measured?
- As voltage
- Expressed as inside relative to outside the cell
Polarized cell
A cell with any electrical gradient (not 0mV)
Depolarization
Less polarized than at rest
Hyperpolarization
More polarized than at rest
Repolarization
Returns towards its resting potential
Dendrites
Branched extensions of a neuron that receive signals from other neurons
Where do changes in cell potentials occur?
The dendrites
Agonists
- substances that bind to receptors and activate them
- Make it more likely that a neuron will reach its threshold membrane potential
Antagonists
- substances that bind to receptors but block them
- make it less likely that a neuron will reach its threshold membrane potential
Action Potential
- brief electrical impulse that travels down a neuron
- allows for the rapid transmission of electrical signals along neurons
The nature of the action potential: step 1
- Resting state
- at rest, most ion channels are closed
The nature of the action potential: step 2
- Depolarization
- some signals cause some Na channels to open
- initiates a slow depolarization
The nature of the action potential: step 3
- Rising phase of the action potential
- When depolarization reaches a certain point, Na channels open, this triggers a massive depolarization
The nature of the action potential: step 4
- Falling phase of the action potential
- Na channels close
- K channels open
The nature of the action potential: step 5
- Undershoot
- Repolarization continues past the resting potential
- This is quickly corrected
Multipolar interneurons
connect neurons together
Motor neuron
carries signals to muscles
Sensory neuron
Controls feelings
Synapse
gap between two neurons where communication occurs
Presynaptic events
- Action potential
- Presynaptic membrane
- Exocytosis of neurotransmitter