Week 6- endocrine disorders Flashcards
What is graves disease associated with?
Hyperthyroidism
what can cause graves disease?
Thyroid stimulating hormone- antibodies that bind to TSH receptors due to an autoimmune reaction against thyroid tissue
Thyroid tumors- most common
What are the signs ans symtoms of graves disease?
Intoelerence to heat fine, straight hair buldging eyes facial flushing enlarged thyroid tachycardia increased BP breast enlargment wieghtloss muscle wasting localised odeama finger clubbing tremors diorreaha menstral changes
what is the pre-hospital treatment for graves disease?
regocnition, supportive care and transport if required
what is a thyroid storm?
an exagerated or florid state of thyrotoxicosis due to a sudden onset of thyroid hyperactivity.
what is a thyroid storm precipertated by?
pts with hyperthyrodism that have surgery, experience trauma, infection or thyroxine ingestion
what is the prehospital treatment for a thyropid storm?
recognition, supportive care and rapid transport
What causes hypothyrodisim
autoimmune reaction that destroyes the thyroid gland
Iodine deficeny where uninhibited TSH production leads to increas in increased precourser (thyrogloblin) but without adequate iodine T3 and T4 cannot be formed
what are the signs and symptoms of hypothyrodisim?
Intolernece to cold reeceding hairline facial/eyelid odeama dull-blank expression extreme fatigue thick tounge slow speech anorexia brittle nails/hair menstral disturbances hairloss apathy dry skin muscle aches and weakness constipation
what is the prehospital treatment for hypothyroidism?
recognition, supportive care and trnasport
what is addisons disease?
insufficent amounts of hormones in the adreanal gland
what are the causes of addisons disease?
autoimmune destruction
what are the signs and symptoms of addisons disease?
bronze pigmentation to skin changes in distribution of hair GI disturbances hypoglycemia postural hypotension weightloss
what is the pre-hospital treatment for addisons disease?
supportive care
oxygen if required
fluids
what is crushing syndrome?
high ;evels of cortosol due to tumor or steriod use
what are the signs and symptoms of crushings disease?
Personality changes moon face increased suseptibility to infection fat deposits on face and back of shoulders osteoporsis CNS irratability NA and fluid retention thin ectermities DI distress think skin with purple striage bruises
what is the pre-hospital treatment for cushings syndorme?
supportive care, manage symptoms, transport- raley an emergency
what is phaechromocytoma?
caused by a begnin tumor releasing hormones in the adrenal gland
what are the sings and symptoms of phaechromocytoma?
persistant hypertension sevre headache diaphorisis tachycardia palpitations pallor nausea/vommiting epigastric/chest pain
what is the prehospital treatment of phaechromocytoma?
supportive care, symptom management and transport
what is hyperpituitarisim?
over production of pituirtey hormons casues by pituitory adenoma
what is gigantism?
young- epiphyseal/growth plates open causes large bones
what is acromegaly?
in older people- growth plates - enlarged face, hands and feetfused=
what is prolactinoma?
wheere there is an over production in prolactin and decrease in levels of sex hormones
