Week 6- Menopause Flashcards
(88 cards)
This is defined as the point in time which there has been a cessation of menstruation for at least 12 consecutive months.
Natural menopause
This occurs following either surgical excision of both ovaries (bilateral oophorectomy) or ovarian function ablation caused by medication, chemo, or radiation.
Induced menopause
Which type of menopause has more severe hot flashes?
Induced
What is premature menopause?
Menopause that occurs before the age of 40.
Normal age range of natural menopause?
40-58 with the average at 52
What are the factors that influence natural menopause?
Lower socioeconomic status Lower body weight Nulliparity Smoking Hx of not using oral contraceptives Cycle lengths of less than 21 days
During menopause the ovaries become resistant to what?
FSH
During menopause the ovaries become more resistant to FSH which causes them to produce less?
Estrogen and androgen
What happens to levels of FSH and LH during menopause?
Increase
What happens to testosterone levels during menopause?
Remain about the same as pre-menopausal levels
What happens to estradiol levels after menopause?
They are lower than in reproductive years
Higher weight/ higher amounts of adipose tissue after menopause =
Higher levels of estrogen
How do you diagnose menopause?
No clinical test to predict or confirm
12 months amenorrhea with other causes ruled out.
What does Asherman’a syndrome cause?
Scar tissue causing amenorrhea
Treatments for vagina dryness during menopause include:
Non-hormonal lubricants
Moisturizers
Mood management during menopause:
Non-hormonal prescription- SSRI/SNRIs
Treatment of sleep disorders during menopause include:
Gabapentin for sleep
Catapres/clonidine
Non-pharm options
If patient had hysterectomy, HT for menopause would include:
Estrogen
If patient has intact uterus need both estrogen and progesterone
Contraindications for estrogen/HT?
- Vagina bleeding (investigate)
- Hx of breast cancer or some form of estrogen dependent cancer
- DVT hx
- MI hx
- CVA hx
- Liver disease
- Pregnancy
How long is it possible to get pregnant after onset of menopausal amenorrhea?
12 months
Women’s health initiative study found:
Estrogen/progesterone therapy was found to be more harmful then beneficial overall
- elevated risk of breast cancer
- elevated risk of CV issues
This is characterized by low bone mass, deterioration of bone tissue, and disruption of bone architecture resulting in reduced bone strength that increases the risk for fracture.
Osteoporosis
What are the 3 types of osteoporosis?
- Primary- associated with aging (estrogen depletion)
- Secondary- response to medication or other disease processes
- Idiopathic- in young adults with no other identified cause
This identifies the number of standard deviations that the patient’s bone mineral density is greater than or less than for a young-adult, gender-matched norm.
T score