Week 7... Flashcards Preview

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Flashcards in Week 7... Deck (20):
1

T/F Iodide inhibits the release of thyroxine from the thyroid gland.

True

2

Which drug inhibits the peripheral conversion of T3 & T4 ?

Propylthiuracil - PTU

3

Clopidegrol is an anti-platelet drug. What is the MAO?

Inhibition of binding of ADP to its receptors on platelets

4

Fludrocortisone is a steroid drug with potent mineralocorticoid activity. What is a known fact about Mineralocorticoid drugs?

It is involve in salt & water balance.

5

The drug Erythropoietin is used to treat?

Anemia in end stage renal failure

6

A 39 year old pregnant woman requires heparin to prevent intravascular clot formation. What is the MOA of Heparin?

Binding of antithrombin III and subsequent rapid inactivation of coagulation factors.

7

Baby Aspirin is a widely used drug to reduce the risk of MI. What is the MOA of Aspirin?

Inhibition of thromboxane A2 synthesis in the platelets

8

Which drug is used to induce or reinforce labor?

Oxytocin

9

What is a major side affect of all anticoagulant drugs?

Hemorrhage

10

Which is the drug of choice for hypothyroidism?

Levothyroxine

11

The drug of choice for treating patients with hypercholesterolemia is?

HMG-CoA reductase inhibitors

12

Tamoxifen is used to treat some forms of breast cancers because of its ability to?

Prevent endogenous estrogen from stimulating tumor growth

13

A 76 year old male complains of progressive difficulty starting stream on urinating & having to get up at least once a night to urinate. A BPH is diagnosed. Finasteride therapy is started & results improve in urine flow & decrease prostate size. What are the drugs MOA?

Inhibition of steroid 5a-reductase

14

Endometrial hyperplasia is the adverse effect of which drug?

Estrogen

15

A 42 year old male with an acute MI is treated with thrombolytic drug, Streptokinase. What is the MOA of thrombolytic drugs.

Activation of Plasminogen to Plasmin

16

Partial Estrogen receptor antagonists in the hypothalamus & used in the tx. of infertility =

Clomiphene

17

A/E's include Flushing & Puritus =

Niacin

18

Interferes with the synthesis of Vit. K dependent clotting factors =

Warfarin

19

Can cause myopathy & Rhabdomyolisis =

HMG CoA-reductase inhibitors

20

Long-term use can cause Osteoporosis =

Glucocorticoids