Flashcards in Week 7... Deck (20):
T/F Iodide inhibits the release of thyroxine from the thyroid gland.
Which drug inhibits the peripheral conversion of T3 & T4 ?
Propylthiuracil - PTU
Clopidegrol is an anti-platelet drug. What is the MAO?
Inhibition of binding of ADP to its receptors on platelets
Fludrocortisone is a steroid drug with potent mineralocorticoid activity. What is a known fact about Mineralocorticoid drugs?
It is involve in salt & water balance.
The drug Erythropoietin is used to treat?
Anemia in end stage renal failure
A 39 year old pregnant woman requires heparin to prevent intravascular clot formation. What is the MOA of Heparin?
Binding of antithrombin III and subsequent rapid inactivation of coagulation factors.
Baby Aspirin is a widely used drug to reduce the risk of MI. What is the MOA of Aspirin?
Inhibition of thromboxane A2 synthesis in the platelets
Which drug is used to induce or reinforce labor?
What is a major side affect of all anticoagulant drugs?
Which is the drug of choice for hypothyroidism?
The drug of choice for treating patients with hypercholesterolemia is?
HMG-CoA reductase inhibitors
Tamoxifen is used to treat some forms of breast cancers because of its ability to?
Prevent endogenous estrogen from stimulating tumor growth
A 76 year old male complains of progressive difficulty starting stream on urinating & having to get up at least once a night to urinate. A BPH is diagnosed. Finasteride therapy is started & results improve in urine flow & decrease prostate size. What are the drugs MOA?
Inhibition of steroid 5a-reductase
Endometrial hyperplasia is the adverse effect of which drug?
A 42 year old male with an acute MI is treated with thrombolytic drug, Streptokinase. What is the MOA of thrombolytic drugs.
Activation of Plasminogen to Plasmin
Partial Estrogen receptor antagonists in the hypothalamus & used in the tx. of infertility =
A/E's include Flushing & Puritus =
Interferes with the synthesis of Vit. K dependent clotting factors =
Can cause myopathy & Rhabdomyolisis =
HMG CoA-reductase inhibitors