Week 7 And 8-Ch 15 Flashcards
(77 cards)
Do medications act diff in older adults
Yes
Do older adults medication require careful dosage adjustment and monitoring
Yes
Medication risks for older adults
Increased risk of interactions and adverse reactions
Med challenges for older adults
Age related changes
Polypharmacy
Increased risk of adverse reactions due to altered pharmokinetics and pharmodynamics
Early sign of adverse reaction to many meds
Mental dysfunction
Age related changes that cause medication issues
Decreased salivary flow and dentition(makes pills hard to swallow)
Kidney and liver changes alter pharmacokinetics
Biological half life on many drugs is longer
-drugs can build up to toxic levels
-liver and kidney tests let us know if drug is appropriate
Changes to body that impact pharmacodynamics
Increased myocardial sensitivity to anesthesia
Increased CNS receptor sensitivity to narcotics, alcohol, and bromides
Altered absorption (kinetics)
There are fewer priblems
Factors that impact absorption
Route
Concentration and solubility
Disease and symptoms
How to maximize absorption
Exercise
Heat
Massage
Preventing dehydration, hypothermia, hypotension, interactions with other meds
Use most effective route
Is drug distribution easy to predict
No
Drug distribution considerations with the older adult
Changes in circulation
Membrane permeability
Body temp
Tissue structure
What decreases drug distribution
Dehydration and hypoalbuminemia
Conditions that decrease metabolism of drug
Dehydration
Hyperthermia
Immobility
Liver disease
Extended half life
Close evaluation of drug clearance
Is detoxification and conjugation of drug reduced or increased
Reduced
Why is kidney efficiency important
Renal system excretes drugs
What organ impacts drugs detoxification and excretion
Liver
What percent of 70 YO use at least 1 drug/ more than 5
95%
68%
Adverse reactions and older adults
Signs and symptoms are different
Takes longer to present itself
May occur even after med is discontinued
May develop suddenly even after long term use
Is mental dysfunction always dramatic or can it be subtle
Can be subtle
Does cause of mental disfunction need to be determined before treating it
Yes. Can cause additional complications.
Causes/risks for med errors
Functional impairment-weak hands
Cognitive limitations
Education limitations
Sensory limitations-hearing, visual
Beers criteria
Identifying high risk drugs for elderly