Week 9 Flashcards
Anti-hypertensives Agents
What is hypertension?
Hypertension is a condition characterized by consistently elevated blood pressure.
What are the main classes of antihypertensive agents?
Diuretics, ACE inhibitors, ARBs, calcium channel blockers, and beta-blockers.
What is the primary action of diuretics in hypertension treatment?
They promote the excretion of sodium and water, reducing blood volume.
Name a common diuretic used in hypertension management.
Thiazide diuretics, such as hydrochlorothiazide.
What does ACE stand for?
Angiotensin-Converting Enzyme.
What is the mechanism of action of ACE inhibitors?
They inhibit the conversion of angiotensin I to angiotensin II, leading to vasodilation.
Name a common ACE inhibitor.
Enalapril (Vasotec).
What is the role of angiotensin II in the body?
It causes vasoconstriction and increases blood pressure.
What are ARBs?
Angiotensin II Receptor Blockers, which block the action of angiotensin II.
Name a common ARB.
Losartan (Cozaar).
What is the primary action of calcium channel blockers?
They block calcium entry into cells, leading to vasodilation and decreased heart contractility.
Name a common calcium channel blocker.
Amlodipine (Norvasc).
What is the effect of beta-blockers on the heart?
They decrease heart rate and myocardial contractility.
Name a common beta-blocker.
Metoprolol (Lopressor).
What is the target blood pressure for low-risk patients?
SBP < 140 mmHg and DBP < 90 mmHg.
What is the recommended blood pressure threshold for initiating treatment in high-risk patients?
SBP ≥ 130 mmHg.
What is the significance of the 2020 CHEP guidelines?
They provide updated recommendations for the diagnosis and management of hypertension.
What is the role of lifestyle modifications in managing hypertension?
They can help lower blood pressure and reduce the need for medication.
What is the recommended follow-up for patients starting antihypertensive therapy?
Follow-up within 1 month to assess blood pressure response.
What is the effect of sodium intake on blood pressure?
High sodium intake can lead to increased blood pressure.
What is the role of potassium in hypertension management?
Adequate potassium intake can help lower blood pressure.
What is the significance of the term “white coat hypertension”?
It refers to elevated blood pressure readings in a clinical setting due to anxiety.
What is the recommended approach for managing resistant hypertension?
Evaluate for secondary causes and consider combination therapy.
What is the primary goal of antihypertensive therapy?
To achieve and maintain target blood pressure levels.